Development Level

Tbio 15 | 11,445
Tchem 3 | 1,598
Tdark 2 | 6,588
Tclin 1 | 613

IMPC Phenotype

abnormal vocalization 21 | 21
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

Carcinoma 12 | 11,493
psoriasis 11 | 6,694
Breast cancer 7 | 3,578
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
medulloblastoma, large-cell 7 | 6,241
ovarian cancer 7 | 8,520
lung carcinoma 6 | 2,843
malignant mesothelioma 6 | 3,232
osteosarcoma 6 | 7,950
glioblastoma 4 | 5,792
group 3 medulloblastoma 4 | 4,104
lung adenocarcinoma 4 | 2,716
lung cancer 4 | 4,740
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
ulcerative colitis 4 | 1,819
Breast Neoplasms 3 | 445
Kidney cancer 3 | 2,613
Mammary Neoplasms 3 | 425
Schizophrenia 3 | 1,160
adrenocortical carcinoma 3 | 1,428
ependymoma 3 | 4,679
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
non-small cell lung cancer 3 | 2,890
spina bifida 3 | 1,074
subependymal giant cell astrocytoma 3 | 2,287
tuberculosis 3 | 2,010
Astrocytoma, Pilocytic 2 | 3,081
Autosomal recessive predisposition 2 | 1,442
Cancer 2 | 2,499
Intellectual disability 2 | 1,016
Liver Cirrhosis, Experimental 2 | 769
Melanoma 2 | 711
Prostatic Neoplasms 2 | 495
acute myeloid leukemia 2 | 783
acute quadriplegic myopathy 2 | 1,158
adult high grade glioma 2 | 3,801
atypical teratoid / rhabdoid tumor 2 | 5,112
breast carcinoma 2 | 1,638
cutaneous lupus erythematosus 2 | 1,057
ductal carcinoma in situ 2 | 1,745
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
invasive ductal carcinoma 2 | 2,951
nasopharyngeal carcinoma 2 | 1,058
non primary Sjogren syndrome sicca 2 | 891
pediatric high grade glioma 2 | 1,064
pituitary cancer 2 | 1,972
primitive neuroectodermal tumor 2 | 3,035
tuberculosis and treatment for 6 months 2 | 409
Absence of secondary sex characteristics 1 | 22
Adenocarcinoma of lung (disorder) 1 | 60
Adrenal Hyperplasia, Congenital 1 | 9
Adrenal hyperplasia 1 | 13
Adrenocorticotropic hormone excess 1 | 5
Adrenogenital Syndrome 1 | 6
Ambiguous Genitalia 1 | 24
Amino Acid Metabolism, Inborn Errors 1 | 13
Antley-Bixler syndrome 1 | 16
Aortic root dilatation 1 | 11
Basal Ganglia Calcification, Idiopathic, 1 1 | 5
Basal ganglia calcification 1 | 27
Bladder exstrophy 1 | 32
Blastomycosis 1 | 12
Brain cancer 1 | 30
Carotid stenosis 1 | 5
Central Nervous System Neoplasms 1 | 2
Cerebral calcification 1 | 43
Coccidioidomycosis 1 | 8
Decreased fertility in females 1 | 20
Decreased male fertility 1 | 7
Decreased plasma renin activity 1 | 9
Decreased testosterone level 1 | 4
Dysdiadochokinesis 1 | 25
Elevated follicle stimulating hormone 1 | 15
Elevated luteinizing hormone 1 | 14
Enlarged polycystic ovaries 1 | 10
Generalized hyperpigmentation 1 | 22
Gynecomastia 1 | 64
HYPERGLYCINURIA (disorder) 1 | 12
Haemorrhage subcutaneous 1 | 10
Head and Neck Neoplasms 1 | 26
Hyperkalemia 1 | 17
Hypokalemia 1 | 52
Hypopituitarism 1 | 40
Hypoplasia of vagina 1 | 14
Infantile uterus 1 | 23
Lipodystrophy 1 | 40
Meningioma 1 | 41
Mental Retardation, X-Linked 1 | 23
Monkeypox 1 | 12
Ocular cancer 1 | 7
Oligomenorrhea 1 | 16
Ovarian Cysts 1 | 41
Paraganglioma 1 | 15
Primary gonadal insufficiency 1 | 9
Pseudohermaphroditism 1 | 16
Rudimentary vagina 1 | 14
Sparse axillary hair 1 | 28
Stomach cancer 1 | 30
Thymoma 1 | 16
Uveal melanoma 1 | 20

Tissue

Digestive Tract 21 | 17,369
Endocrine System 21 | 18,159
Liver and Pancreas 21 | 16,750
Male tissues 21 | 17,142
Respiratory system 21 | 16,393
Skin and soft tissues 21 | 17,230
Female tissues 20 | 17,400
Nervous System 20 | 16,725
Urinary Tract 20 | 16,678
Blood and immune system 19 | 16,909
Cardiovascular System 18 | 15,192

Target Family

Enzyme 10 | 4,145
Non-IDG 8 | 12,091
Ion Channel 1 | 344
Kinase 1 | 634
Transporter 1 | 473

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
F-box only protein 11 FBXO11 Tbio Non-IDG -1.53905 34.1 258
ER membrane protein complex subunit 10 EMC10 Tbio Non-IDG -1.41680 25.5 60
Patched domain-containing protein 1 PTCHD1 Tbio Non-IDG -0.84569 7.72 81
Synemin SYNM Tbio Non-IDG -1.91854 92.6 68
Sodium-dependent phosphate transporter 2 SLC20A2 Tbio Transporter -2.29276 197.3 107
Transmembrane 4 L6 family member 4 TM4SF4 Tbio Non-IDG -0.84630 8.49 106
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 PLCB2 Tbio Enzyme -2.14048 137.8 104
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 PFKFB4 Tchem Enzyme -1.28108 21.2 110
Steroid 17-alpha-hydroxylase/17,20 lyase CYP17A1 Tclin Enzyme -3.09734 1226.2 369
Transmembrane protein 256 TMEM256 Tdark Non-IDG 0.15 0.62 15