Development Level

Tbio 21 | 11,445
Tchem 3 | 1,598
Tdark 1 | 6,588

IMPC Phenotype

abnormal vibrissa morphology 25 | 25
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

Carcinoma 14 | 11,493
ovarian cancer 13 | 8,520
psoriasis 11 | 6,694
osteosarcoma 9 | 7,950
ependymoma 7 | 4,679
glioblastoma 7 | 5,792
medulloblastoma, large-cell 7 | 6,241
adult high grade glioma 6 | 3,801
lung cancer 6 | 4,740
primitive neuroectodermal tumor 6 | 3,035
Astrocytoma, Pilocytic 5 | 3,081
cystic fibrosis 5 | 1,696
invasive ductal carcinoma 5 | 2,951
tuberculosis 5 | 2,010
Autosomal recessive predisposition 4 | 1,442
Breast cancer 4 | 3,578
Cancer 4 | 2,499
atypical teratoid / rhabdoid tumor 4 | 5,112
breast carcinoma 4 | 1,638
group 3 medulloblastoma 4 | 4,104
interstitial cystitis 4 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
lung carcinoma 4 | 2,843
non-small cell lung cancer 4 | 2,890
oligodendroglioma 4 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
spina bifida 4 | 1,074
ulcerative colitis 4 | 1,819
Atopic dermatitis 3 | 952
Multiple myeloma 3 | 1,332
Palmoplantar keratosis 3 | 74
Rheumatoid arthritis 3 | 1,191
astrocytic glioma 3 | 2,597
diabetes mellitus 3 | 1,728
lung adenocarcinoma 3 | 2,716
periodontitis 3 | 293
primary Sjogren syndrome 3 | 735
subependymal giant cell astrocytoma 3 | 2,287
Alzheimer's disease 2 | 658
Asthma 2 | 385
Broad flat nasal bridge 2 | 236
Cataract 2 | 297
Chronic obstructive pulmonary disease 2 | 184
Coloboma 2 | 51
Colorectal Neoplasms 2 | 243
Conductive hearing loss 2 | 123
Coronary artery disease 2 | 268
Dull intelligence 2 | 645
Eosinophilia 2 | 28
Epilepsy 2 | 792
Erythema 2 | 58
Flushing 2 | 60
Hypertensive disease 2 | 292
Inflammatory bowel disease 2 | 151
Influenza 2 | 142
Intellectual disability 2 | 1,016
Keratitis 2 | 62
Kidney cancer 2 | 2,613
Low intelligence 2 | 645
Mental Retardation 2 | 645
Mental deficiency 2 | 645
Nasal bridge wide 2 | 236
Nephrotic Syndrome 2 | 78
Obesity 2 | 678
Poor school performance 2 | 645
Retinitis Pigmentosa 2 | 226
Rosacea 2 | 25
Schizophrenia 2 | 1,160
Seizures 2 | 596
Usher syndrome 2 | 32
adrenocortical carcinoma 2 | 1,428
atypical teratoid/rhabdoid tumor 2 | 357
dermatomyositis 2 | 966
ductal carcinoma in situ 2 | 1,745
esophageal adenocarcinoma 2 | 737
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
malignant mesothelioma 2 | 3,232
medulloblastoma 2 | 720
Acquired thrombocytopenia 1 | 8
Adrenogenital disorder 1 | 6
Bursitis 1 | 10
Congenital hypoplastic anemia 1 | 8
Corneal abrasion 1 | 5
Cyclitis 1 | 5
Diagnostic Test for Cushing's Syndrome 1 | 5
Discoid lupus erythematosus 1 | 7
Erythroblastic Anemia 1 | 5
Erythroderma 1 | 5
Granuloma annulare 1 | 5
Herpes zoster keratitis 1 | 5
Infective blepharitis 1 | 5
Iridocyclitis 1 | 19
Löffler's syndrome 1 | 5
Meibomianitis 1 | 4
Ocular rosacea 1 | 4
Pemphigus 1 | 23
Pruritus of genital organs 1 | 5
Punctate keratopathy 1 | 5
Rheumatic heart disease 1 | 10
Synovitis due to Osteoarthritis 1 | 5

Tissue

Digestive Tract 25 | 17,369
Endocrine System 25 | 18,159
Female tissues 25 | 17,400
Skin and soft tissues 24 | 17,230
Male tissues 23 | 17,142
Nervous System 23 | 16,725
Urinary Tract 23 | 16,678
Blood and immune system 22 | 16,909
Liver and Pancreas 21 | 16,750
Cardiovascular System 18 | 15,192
Respiratory system 18 | 16,393

Target Family

Non-IDG 11 | 12,091
Enzyme 10 | 4,145
Transporter 3 | 473
Transcription Factor 1 | 1,400

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
E3 ubiquitin-protein ligase TRIM39 TRIM39 Tbio Enzyme -1.24729 16.2 194
Ankyrin repeat and SAM domain-containing protein 4B ANKS4B Tbio Non-IDG -0.12494 1.58 59
Plasma membrane calcium-transporting ATPase 1 ATP2B1 Tbio Transporter -2.01694 100.0 110
Zinc finger BED domain-containing protein 5 ZBED5 Tdark Non-IDG -0.11090 1.17 52
Protein crumbs homolog 2 CRB2 Tbio Non-IDG -1.44852 30.9 92
Loricrin LOR Tbio Non-IDG -2.58018 365.6 49
Annexin A6 ANXA6 Tbio Non-IDG -2.44893 298.8 381
Clarin-1 CLRN1 Tbio Non-IDG -1.42455 26.7 29
ATP-binding cassette sub-family B member 6, mitochondrial ABCB6 Tbio Transporter -2.65393 430.3 137
Rho guanine nucleotide exchange factor 4 ARHGEF4 Tbio Non-IDG -1.40554 28.0 126