Development Level

Tbio 34 | 11,445
Tchem 5 | 1,598
Tdark 3 | 6,588
Tclin 1 | 613

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

abnormal testis morphology 43 | 43
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

ovarian cancer 24 | 8,520
osteosarcoma 23 | 7,950
Carcinoma 20 | 11,493
glioblastoma 15 | 5,792
psoriasis 15 | 6,694
intraductal papillary-mucinous adenoma (IPMA) 14 | 2,955
medulloblastoma, large-cell 14 | 6,241
oligodendroglioma 14 | 2,850
ependymoma 13 | 4,679
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,291
lung carcinoma 11 | 2,843
Astrocytoma, Pilocytic 10 | 3,081
Breast cancer 10 | 3,578
Cancer 10 | 2,499
adult high grade glioma 10 | 3,801
atypical teratoid / rhabdoid tumor 10 | 5,112
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,989
lung adenocarcinoma 10 | 2,716
non-small cell lung cancer 10 | 2,890
astrocytic glioma 9 | 2,597
group 3 medulloblastoma 9 | 4,104
lung cancer 9 | 4,740
malignant mesothelioma 9 | 3,232
pituitary cancer 9 | 1,972
Atopic dermatitis 8 | 952
group 4 medulloblastoma 8 | 1,855
interstitial cystitis 8 | 2,312
invasive ductal carcinoma 8 | 2,951
subependymal giant cell astrocytoma 8 | 2,287
ulcerative colitis 8 | 1,819
Pick disease 7 | 1,894
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,962
primitive neuroectodermal tumor 7 | 3,035
primary pancreatic ductal adenocarcinoma 6 | 1,109
Obesity 5 | 678
Rheumatoid arthritis 5 | 1,191
Schizophrenia 5 | 1,160
diabetes mellitus 5 | 1,728
ductal carcinoma in situ 5 | 1,745
pancreatic cancer 5 | 2,398
Hypertensive disease 4 | 292
Liver Cirrhosis, Experimental 4 | 769
Multiple myeloma 4 | 1,332
Prostatic Neoplasms 4 | 495
adrenocortical carcinoma 4 | 1,428
astrocytoma 4 | 1,146
atypical teratoid/rhabdoid tumor 4 | 357
breast carcinoma 4 | 1,638
cutaneous lupus erythematosus 4 | 1,057
cystic fibrosis 4 | 1,696
progressive supranuclear palsy 4 | 676
Acquired metabolic disease 3 | 336
Arthritis, Rheumatoid 3 | 174
Autosomal recessive predisposition 3 | 1,442
Bipolar Disorder 3 | 666
Heart disease 3 | 306
Kidney cancer 3 | 2,613
Kidney disease 3 | 430
Multiple Sclerosis 3 | 540
Reperfusion Injury 3 | 86
Retinitis Pigmentosa 3 | 226
Short stature 3 | 531
Stomach Neoplasms 3 | 300
active Crohn's disease 3 | 922
pediatric high grade glioma 3 | 1,064
posterior fossa group A ependymoma 3 | 468
spina bifida 3 | 1,074
tuberculosis 3 | 2,010
Anemia 2 | 365
Arthritis, Juvenile 2 | 126
Attention deficit hyperactivity disorder 2 | 278
Autistic Disorder 2 | 364
Bladder Neoplasm 2 | 112
Brain Ischemia 2 | 110
Carcinoma, Transitional Cell 2 | 32
Cognitive delay 2 | 608
Diabetes Mellitus, Non-Insulin-Dependent 2 | 145
Global developmental delay 2 | 608
Hypertension 2 | 396
Hypogonadism 2 | 173
Increase in blood pressure 2 | 119
Influenza 2 | 142
Juvenile arthritis 2 | 126
Long face 2 | 71
Lung Neoplasms 2 | 232
Mental Depression 2 | 333
Mental and motor retardation 2 | 608
Muscle hypotonia 2 | 571
Osteoporosis 2 | 363
Type 2 diabetes mellitus 2 | 272
Uranostaphyloschisis 2 | 167
Urinary Bladder Neoplasms 2 | 114
Waldenstrons macroglobulinemia 2 | 765
active ulcerative colitis 2 | 764
colon cancer 2 | 1,478
esophageal adenocarcinoma 2 | 737
gastric cancer 2 | 459
juvenile dermatomyositis 2 | 1,187
primary Sjogren syndrome 2 | 735
sonic hedgehog group medulloblastoma 2 | 467

Tissue

Digestive Tract 42 | 17,369
Female tissues 42 | 17,400
Nervous System 42 | 16,725
Blood and immune system 41 | 16,909
Endocrine System 41 | 18,159
Male tissues 41 | 17,142
Skin and soft tissues 41 | 17,230
Liver and Pancreas 40 | 16,750
Respiratory system 39 | 16,393
Urinary Tract 38 | 16,678
Cardiovascular System 37 | 15,192

Target Family

Non-IDG 23 | 12,091
Enzyme 12 | 4,145
Kinase 3 | 634
Transcription Factor 3 | 1,400
GPCR 1 | 408
Ion Channel 1 | 344

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Mitotic spindle assembly checkpoint protein MAD1 MAD1L1 Tbio Non-IDG -1.17500 13.6 283
SLIT and NTRK-like protein 1 SLITRK1 Tbio Non-IDG -2.74906 555.5 206
Gamma-aminobutyric acid receptor subunit rho-2 GABRR2 Tbio Ion Channel -1.74365 53.9 92
Tyrosine-protein kinase Blk BLK Tchem Kinase -1.88753 81.6 418
Sodium-dependent lysophosphatidylcholine symporter 1 MFSD2A Tbio Non-IDG -1.40175 26.3 73
Cytoglobin CYGB Tbio Non-IDG -3.10582 1269.7 202
Platelet glycoprotein Ib beta chain GP1BB Tbio Non-IDG -1.79873 57.4 87
ADM2 ADM2 Tbio Non-IDG -2.49800 325.5 139
Endonuclease G, mitochondrial ENDOG Tbio Enzyme -2.22791 175.9 334
Nephrocystin-1 NPHP1 Tbio Non-IDG -1.76149 55.3 96