Development Level

Tbio 12 | 10,625
Tdark 3 | 7,003
Tchem 2 | 1,890

IMPC Term

abnormal tail morphology 17 | 17
preweaning lethality, complete... 633 | 633
preweaning lethality, incomple... 260 | 260
abnormal behavior 226 | 226
decreased lean body mass 195 | 195
embryonic lethality prior to t... 187 | 187
decreased total body fat amoun... 186 | 186
decreased body weight 174 | 174
decreased bone mineral content 157 | 157
embryonic lethality prior to o... 148 | 148
abnormal bone structure 131 | 131
increased or absent threshold ... 128 | 128
decreased bone mineral density 126 | 126
decreased grip strength 123 | 123
decreased circulating glucose ... 121 | 121
increased circulating alkaline... 119 | 119
abnormal embryo size 112 | 112
enlarged heart 111 | 111
decreased body length 108 | 108
hyperactivity 108 | 108
increased lean body mass 107 | 107
abnormal retina morphology 100 | 100
increased mean corpuscular hem... 93 | 93
increased bone mineral content 92 | 92
increased mean corpuscular vol... 91 | 91
hypoactivity 89 | 89
decreased circulating choleste... 85 | 85
decreased circulating triglyce... 83 | 83
increased grip strength 83 | 83
short tibia 82 | 82
decreased circulating serum al... 79 | 79
decreased circulating HDL chol... 77 | 77
decreased circulating insulin ... 75 | 75
abnormal lens morphology 73 | 73
increased circulating sodium l... 71 | 71
increased fasted circulating g... 68 | 68
prenatal lethality prior to he... 64 | 64
abnormal sleep behavior 63 | 63
increased circulating HDL chol... 63 | 63
decreased lumbar vertebrae num... 62 | 62
increased sacral vertebrae num... 62 | 62
male infertility 62 | 62
abnormal retinal pigmentation 61 | 61
decreased rib number 59 | 59
increased total body fat amoun... 57 | 57
improved glucose tolerance 56 | 56
increased exploration in new e... 56 | 56
abnormal bone mineralization 55 | 55
abnormal coat/hair pigmentatio... 54 | 54
decreased leukocyte cell numbe... 54 | 54
decreased circulating alanine ... 53 | 53
decreased hemoglobin content 53 | 53
increased circulating choleste... 53 | 53
abnormal behavioral response t... 52 | 52
decreased prepulse inhibition 52 | 52
impaired glucose tolerance 52 | 52
increased bone mineral density 52 | 52
abnormal gait 51 | 51
abnormal heart morphology 51 | 51
decreased mean corpuscular vol... 50 | 50
decreased caudal vertebrae num... 49 | 49
decreased fasted circulating g... 49 | 49
decreased startle reflex 48 | 48
abnormal seminal vesicle morph... 47 | 47
thrombocytopenia 46 | 46
increased hemoglobin content 45 | 45
decreased heart weight 44 | 44
increased blood urea nitrogen ... 44 | 44
decreased erythrocyte cell num... 43 | 43
increased circulating chloride... 43 | 43
increased body weight 42 | 42
decreased circulating alkaline... 41 | 41
decreased circulating total pr... 41 | 41
decreased eosinophil cell numb... 41 | 41
increased rib number 41 | 41
decreased circulating free fat... 39 | 39
abnormal eye morphology 38 | 38
increased startle reflex 38 | 38
abnormal neural tube closure 37 | 37
decreased circulating LDL chol... 37 | 37
decreased neutrophil cell numb... 37 | 37
increased heart weight 37 | 37
increased leukocyte cell numbe... 37 | 37
small testis 37 | 37
abnormal spleen morphology 36 | 36
increased hematocrit 36 | 36
cardiovascular system phenotyp... 35 | 35
limb grasping 35 | 35
decreased mean corpuscular hem... 34 | 34
female infertility 34 | 34
tremors 34 | 34
decreased circulating calcium ... 33 | 33
abnormal cranium morphology 32 | 32
decreased circulating chloride... 32 | 32
decreased threshold for audito... 32 | 32
increased circulating calcium ... 32 | 32
abnormal epididymis morphology 31 | 31
decreased T cell number 31 | 31
decreased blood urea nitrogen ... 31 | 31
decreased circulating fructosa... 31 | 31
increased circulating potassiu... 31 | 31

Disease

osteosarcoma 10 | 7,933
ovarian cancer 10 | 8,484
malignant mesothelioma 8 | 3,162
psoriasis 8 | 6,685
glioblastoma 7 | 5,572
lung cancer 7 | 4,466
medulloblastoma, large-cell 7 | 6,234
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,988
Breast cancer 5 | 3,094
Cancer 5 | 2,346
adrenocortical carcinoma 5 | 1,427
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,956
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,289
lung carcinoma 5 | 2,844
progressive supranuclear palsy 5 | 674
Carcinoma 4 | 2,147
ductal carcinoma in situ 4 | 1,745
invasive ductal carcinoma 4 | 2,950
pituitary cancer 4 | 1,972
Atopic dermatitis 3 | 944
Pick disease 3 | 1,893
atypical teratoid / rhabdoid tumor 3 | 4,369
breast carcinoma 3 | 1,614
gastric carcinoma 3 | 832
group 3 medulloblastoma 3 | 2,254
juvenile dermatomyositis 3 | 1,189
nasopharyngeal carcinoma 3 | 1,056
pilocytic astrocytoma 3 | 3,086
subependymal giant cell astrocytoma 3 | 2,287
Alzheimer's disease 2 | 644
Craniofacial Abnormalities 2 | 147
Down syndrome 2 | 548
IGA Glomerulonephritis 2 | 454
Infantile refsum disease 2 | 19
Rheumatoid Arthritis 2 | 1,160
Zellweger Syndrome 2 | 38
acute quadriplegic myopathy 2 | 1,157
adult high grade glioma 2 | 2,148
aldosterone-producing adenoma 2 | 664
astrocytoma 2 | 1,493
colon cancer 2 | 1,475
cystic fibrosis 2 | 1,665
dermatomyositis 2 | 933
ependymoma 2 | 2,514
group 4 medulloblastoma 2 | 1,875
hereditary spastic paraplegia 2 | 313
interstitial cystitis 2 | 2,299
lung adenocarcinoma 2 | 2,713
non-small cell lung cancer 2 | 2,798
pancreatic cancer 2 | 2,300
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,795
pediatric high grade glioma 2 | 2,712
posterior fossa group B ependymoma 2 | 1,530
spina bifida 2 | 1,064
tuberculosis and treatment for 6 months 2 | 686
ulcerative colitis 2 | 2,087
Agraphia 1 | 6
Amnestic disorder 1 | 37
Amyloidosis 1 | 68
Aphasia 1 | 22
Apraxia 1 | 25
Calcinosis 1 | 62
Cardiomyopathy, Dilated 1 | 47
Central sleep apnea 1 | 12
Cleft palate 1 | 125
Cornea plana 1 | 12
Diabetic Retinopathy 1 | 53
Dyslexia 1 | 36
Dyspepsia 1 | 34
Frontotemporal dementia 1 | 41
Gaucher disease type 3 1 | 76
Heart failure 1 | 80
Hemolytic anemia 1 | 66
Hyperparathyroidism 1 | 43
Hyperphosphatemia 1 | 32
Hypochondroplasia 1 | 11
Hypophosphatemia 1 | 31
Kidney Diseases 1 | 86
Lung diseases 1 | 48
Mammary Neoplasms 1 | 410
Motor neuron disease 1 | 39
Myopia 1 | 99
Nephritis 1 | 29
Nerve Degeneration 1 | 73
Neutropenia 1 | 78
Obstructive sleep apnea 1 | 28
Osteomalacia 1 | 28
Pick's disease 1 | 14
Posterior amorphous corneal dystrophy 1 | 9
Prosopagnosia 1 | 4
Pulmonary Fibrosis 1 | 66
Restless legs syndrome 1 | 28
Retinal disease 1 | 16
Rickets 1 | 42
Seckel syndrome 1 | 34
Sensorineural hearing loss 1 | 107
Synovitis 1 | 38
Tooth agenesis 1 | 36
Visual agnosia 1 | 3
fascioscapulohumeral muscular dystrophy 1 | 100

Tissue

Blood and immune system 17 | 17,995
Cardiovascular System 17 | 17,958
Endocrine System 17 | 18,512
Female tissues 17 | 18,647
Liver and Pancreas 17 | 18,136
Male tissues 17 | 17,969
Nervous System 17 | 18,561
Skin and soft tissues 17 | 18,115
Digestive Tract 16 | 18,473
Respiratory system 16 | 17,484
Urinary Tract 16 | 18,444

Target Family

Non-IDG 9 | 11,971
Enzyme 5 | 4,146
Transcription Factor 2 | 1,400
Epigenetic 1 | 242

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Lumican LUM Tbio Non-IDG -2.67820 509.4 209
Phosphate-regulating neutral endopeptidase PHEX Tbio Enzyme -3.21267 1694.4 98
Homeobox protein BarH-like 2 BARX2 Tbio Transcription Factor -1.11430 18.9 62
Mis18-binding protein 1 MIS18BP1 Tdark Non-IDG -1.03073 10.4 42
Centromere protein J CENPJ Tbio Non-IDG -1.75521 57.1 86
Presenilin-1 PSEN1 Tchem Enzyme -3.52148 3533.8 593
Zinc finger protein ubi-d4 DPF2 Tbio Epigenetic -1.61532 42.6 204
Proline-serine-threonine phosphatase-interacting protein 2 PSTPIP2 Tdark Enzyme -0.94024 10.2 42
Proprotein convertase subtilisin/kexin type 5 PCSK5 Tchem Enzyme -2.83840 697.2 118
Deoxyribonuclease-1-like 2 DNASE1L2 Tbio Enzyme -1.64002 46.4 20