Development Level

Tbio 9 | 11,445
Tdark 3 | 6,588
Tchem 2 | 1,598
Tclin 1 | 613

IMPC Phenotype

abnormal startle reflex 15 | 15
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

Carcinoma 11 | 11,493
lung cancer 10 | 4,740
psoriasis 10 | 6,694
glioblastoma 9 | 5,792
medulloblastoma, large-cell 9 | 6,241
osteosarcoma 9 | 7,950
atypical teratoid / rhabdoid tumor 8 | 5,112
ependymoma 8 | 4,679
Breast cancer 7 | 3,578
malignant mesothelioma 7 | 3,232
Cancer 6 | 2,499
group 3 medulloblastoma 6 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
ovarian cancer 6 | 8,520
primitive neuroectodermal tumor 6 | 3,035
Astrocytoma, Pilocytic 5 | 3,081
adult high grade glioma 5 | 3,801
ductal carcinoma in situ 5 | 1,745
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
invasive ductal carcinoma 5 | 2,951
pituitary cancer 5 | 1,972
Osteoporosis 4 | 363
breast carcinoma 4 | 1,638
non-small cell lung cancer 4 | 2,890
pediatric high grade glioma 4 | 1,064
Breast Neoplasms 3 | 445
Kidney cancer 3 | 2,613
Mammary Neoplasms 3 | 425
Melanoma 3 | 711
Schizophrenia 3 | 1,160
Skin cancer 3 | 469
astrocytic glioma 3 | 2,597
cystic fibrosis 3 | 1,696
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
lung carcinoma 3 | 2,843
pancreatic cancer 3 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
subependymal giant cell astrocytoma 3 | 2,287
tuberculosis and treatment for 6 months 3 | 409
Ambiguous Genitalia 2 | 24
Cognitive delay 2 | 608
Colonic Neoplasms 2 | 142
Colorectal Neoplasms 2 | 243
Cryptorchidism 2 | 296
Dull intelligence 2 | 645
Dysgerminoma 2 | 11
Gamma chain deficiency 2 | 7
Global developmental delay 2 | 608
Hypogonadism, Isolated Hypogonadotropic 2 | 71
Hypogonadotropic hypogonadism 2 | 89
Intellectual disability 2 | 1,016
Kidney disease 2 | 430
Leukemia 2 | 104
Liver Cirrhosis, Experimental 2 | 769
Liver cancer 2 | 604
Liver disease 2 | 237
Low intelligence 2 | 645
Lung Neoplasms 2 | 232
Lymphoid leukemia 2 | 160
MYELODYSPLASTIC SYNDROME 2 | 53
Male infertility 2 | 206
Mental Retardation 2 | 645
Mental and motor retardation 2 | 608
Mental deficiency 2 | 645
Muscle hypotonia 2 | 571
Ovarian Neoplasms 2 | 102
Pick disease 2 | 1,894
Poor school performance 2 | 645
Radio-ulnar synostosis-amegakaryocytic thrombocytopenia syndrome 2 | 3
Radioulnar synostosis 2 | 35
Small head 2 | 374
active Crohn's disease 2 | 922
active ulcerative colitis 2 | 764
adrenocortical carcinoma 2 | 1,428
astrocytoma 2 | 1,146
chronic rhinosinusitis 2 | 512
fibroadenoma 2 | 559
gastric carcinoma 2 | 807
lung adenocarcinoma 2 | 2,716
oligodendroglioma 2 | 2,850
ovarian neoplasm 2 | 99
spina bifida 2 | 1,074
tuberculosis 2 | 2,010
Abnormality of the musculature 1 | 16
Adrenal cortical adenocarcinoma 1 | 4
Bladder exstrophy 1 | 32
Decreased testosterone in males 1 | 28
Heart Injuries 1 | 3
Hereditary nonpolyposis colorectal carcinoma 1 | 18
Increased gastric cancer 1 | 21
Leiomyosarcoma of uterus 1 | 13
Leukemia, Lymphoid 1 | 8
Micronodular cirrhosis 1 | 12
Retinitis pigmentosa 4 1 | 38
Sparse axillary hair 1 | 28
Subacute progressive viral hepatitis 1 | 9
Transitional cell carcinoma of bladder 1 | 17
Wernicke-Korsakoff syndrome 1 | 10
esophageal cancer 1 | 22
osteoporosis-pseudoglioma syndrome 1 | 9

Tissue

Blood and immune system 13 | 16,909
Cardiovascular System 13 | 15,192
Digestive Tract 13 | 17,369
Endocrine System 13 | 18,159
Female tissues 13 | 17,400
Liver and Pancreas 13 | 16,750
Male tissues 13 | 17,142
Nervous System 13 | 16,725
Respiratory system 13 | 16,393
Skin and soft tissues 13 | 17,230
Urinary Tract 13 | 16,678

Target Family

Non-IDG 7 | 12,091
Kinase 2 | 634
Enzyme 1 | 4,145
GPCR 1 | 408
Ion Channel 1 | 344
TF/Epigenetic 1 | 38
Transcription Factor 1 | 1,400
Transporter 1 | 473

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
F-box only protein 11 FBXO11 Tbio Non-IDG -1.53905 34.1 258
Putative sodium-coupled neutral amino acid transporter 10 SLC38A10 Tdark Transporter -0.27712 1.71 25
MDS1 and EVI1 complex locus protein MDS1 MECOM Tbio Non-IDG -1.84060 124.5 0
B9 domain-containing protein 1 B9D1 Tdark Non-IDG -0.61316 3.72 43
Cadherin EGF LAG seven-pass G-type receptor 1 CELSR1 Tbio GPCR -1.47924 34.4 115
Xylulose kinase XYLB Tbio Kinase -1.97293 93.1 74
Fibroblast growth factor 11 FGF11 Tbio Non-IDG -1.03057 9.36 139
Mitogen-activated protein kinase kinase kinase 1 MAP3K1 Tchem Kinase -2.12399 119.4 334
Transmembrane protein 183A TMEM183A Tdark Non-IDG 0.05 1.47 3
Catenin beta-1 CTNNB1 Tchem Non-IDG -3.99948 9786.0 3058