Development Level

Tbio 25 | 10,625
Tdark 6 | 7,003
Tchem 4 | 1,890
Tclin 1 | 602

Collection

Eligible Kinase Proteins 2 | 134

IMPC Term

abnormal spleen morphology 36 | 36
preweaning lethality, complete... 633 | 633
preweaning lethality, incomple... 260 | 260
abnormal behavior 226 | 226
decreased lean body mass 195 | 195
embryonic lethality prior to t... 187 | 187
decreased total body fat amoun... 186 | 186
decreased body weight 174 | 174
decreased bone mineral content 157 | 157
embryonic lethality prior to o... 148 | 148
abnormal bone structure 131 | 131
increased or absent threshold ... 128 | 128
decreased bone mineral density 126 | 126
decreased grip strength 123 | 123
decreased circulating glucose ... 121 | 121
increased circulating alkaline... 119 | 119
abnormal embryo size 112 | 112
enlarged heart 111 | 111
decreased body length 108 | 108
hyperactivity 108 | 108
increased lean body mass 107 | 107
abnormal retina morphology 100 | 100
increased mean corpuscular hem... 93 | 93
increased bone mineral content 92 | 92
increased mean corpuscular vol... 91 | 91
hypoactivity 89 | 89
decreased circulating choleste... 85 | 85
decreased circulating triglyce... 83 | 83
increased grip strength 83 | 83
short tibia 82 | 82
decreased circulating serum al... 79 | 79
decreased circulating HDL chol... 77 | 77
decreased circulating insulin ... 75 | 75
abnormal lens morphology 73 | 73
increased circulating sodium l... 71 | 71
increased fasted circulating g... 68 | 68
prenatal lethality prior to he... 64 | 64
abnormal sleep behavior 63 | 63
increased circulating HDL chol... 63 | 63
decreased lumbar vertebrae num... 62 | 62
increased sacral vertebrae num... 62 | 62
male infertility 62 | 62
abnormal retinal pigmentation 61 | 61
decreased rib number 59 | 59
increased total body fat amoun... 57 | 57
improved glucose tolerance 56 | 56
increased exploration in new e... 56 | 56
abnormal bone mineralization 55 | 55
abnormal coat/hair pigmentatio... 54 | 54
decreased leukocyte cell numbe... 54 | 54
decreased circulating alanine ... 53 | 53
decreased hemoglobin content 53 | 53
increased circulating choleste... 53 | 53
abnormal behavioral response t... 52 | 52
decreased prepulse inhibition 52 | 52
impaired glucose tolerance 52 | 52
increased bone mineral density 52 | 52
abnormal gait 51 | 51
abnormal heart morphology 51 | 51
decreased mean corpuscular vol... 50 | 50
decreased caudal vertebrae num... 49 | 49
decreased fasted circulating g... 49 | 49
decreased startle reflex 48 | 48
abnormal seminal vesicle morph... 47 | 47
thrombocytopenia 46 | 46
increased hemoglobin content 45 | 45
decreased heart weight 44 | 44
increased blood urea nitrogen ... 44 | 44
decreased erythrocyte cell num... 43 | 43
increased circulating chloride... 43 | 43
increased body weight 42 | 42
decreased circulating alkaline... 41 | 41
decreased circulating total pr... 41 | 41
decreased eosinophil cell numb... 41 | 41
increased rib number 41 | 41
decreased circulating free fat... 39 | 39
abnormal eye morphology 38 | 38
increased startle reflex 38 | 38
abnormal neural tube closure 37 | 37
decreased circulating LDL chol... 37 | 37
decreased neutrophil cell numb... 37 | 37
increased heart weight 37 | 37
increased leukocyte cell numbe... 37 | 37
small testis 37 | 37
increased hematocrit 36 | 36
cardiovascular system phenotyp... 35 | 35
limb grasping 35 | 35
decreased mean corpuscular hem... 34 | 34
female infertility 34 | 34
tremors 34 | 34
decreased circulating calcium ... 33 | 33
abnormal cranium morphology 32 | 32
decreased circulating chloride... 32 | 32
decreased threshold for audito... 32 | 32
increased circulating calcium ... 32 | 32
abnormal epididymis morphology 31 | 31
decreased T cell number 31 | 31
decreased blood urea nitrogen ... 31 | 31
decreased circulating fructosa... 31 | 31
increased circulating potassiu... 31 | 31

Disease

ovarian cancer 19 | 8,484
psoriasis 17 | 6,685
osteosarcoma 16 | 7,933
medulloblastoma, large-cell 13 | 6,234
glioblastoma 11 | 5,572
lung cancer 11 | 4,466
atypical teratoid / rhabdoid tumor 9 | 4,369
subependymal giant cell astrocytoma 9 | 2,287
Breast cancer 8 | 3,094
ductal carcinoma in situ 8 | 1,745
invasive ductal carcinoma 8 | 2,950
malignant mesothelioma 8 | 3,162
breast carcinoma 7 | 1,614
interstitial cystitis 7 | 2,299
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,289
cystic fibrosis 6 | 1,665
group 3 medulloblastoma 6 | 2,254
non-small cell lung cancer 6 | 2,798
pituitary cancer 6 | 1,972
primitive neuroectodermal tumor 6 | 3,031
Prostatic Neoplasms 5 | 471
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,956
lung adenocarcinoma 5 | 2,713
lung carcinoma 5 | 2,844
oligodendroglioma 5 | 2,849
pancreatic cancer 5 | 2,300
posterior fossa group B ependymoma 5 | 1,530
Cancer 4 | 2,346
Pick disease 4 | 1,893
astrocytic glioma 4 | 2,241
astrocytoma 4 | 1,493
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,988
medulloblastoma 4 | 1,524
primary pancreatic ductal adenocarcinoma 4 | 1,271
spina bifida 4 | 1,064
Rheumatoid Arthritis 3 | 1,160
Stomach Neoplasms 3 | 282
adrenocortical carcinoma 3 | 1,427
adult high grade glioma 3 | 2,148
cutaneous lupus erythematosus 3 | 1,056
fibroadenoma 3 | 557
interstitial lung disease 3 | 291
juvenile dermatomyositis 3 | 1,189
pediatric high grade glioma 3 | 2,712
pilocytic astrocytoma 3 | 3,086
ulcerative colitis 3 | 2,087
Bladder Neoplasm 2 | 109
Chronic Lymphocytic Leukemia 2 | 242
IGA Glomerulonephritis 2 | 454
Intellectual disability 2 | 573
Joubert syndrome 2 | 61
Meckel syndrome 2 | 48
Schizophrenia 2 | 501
active Crohn's disease 2 | 918
acute myeloid leukemia 2 | 780
acute quadriplegic myopathy 2 | 1,157
aldosterone-producing adenoma 2 | 664
atypical teratoid/rhabdoid tumor 2 | 1,095
colon cancer 2 | 1,475
ependymoma 2 | 2,514
gastric cancer 2 | 430
gastric carcinoma 2 | 832
glioblastoma multiforme 2 | 347
group 4 medulloblastoma 2 | 1,875
hepatocellular carcinoma 2 | 532
hereditary spastic paraplegia 2 | 313
pancreatic carcinoma 2 | 567
posterior fossa group A ependymoma 2 | 1,511
progressive supranuclear palsy 2 | 674
sonic hedgehog group medulloblastoma 2 | 1,482
Adenoid Cystic Carcinoma 1 | 99
Amyotrophic lateral sclerosis type 3 1 | 15
Anemia 1 | 252
Arsenic Poisoning 1 | 59
Autistic Disorder 1 | 320
Carcinoma, Transitional Cell 1 | 31
Cerebral palsy 1 | 28
Colonic Neoplasms 1 | 126
Dermatologic disorders 1 | 65
Disease Progression 1 | 125
Epilepsy 1 | 346
Gaucher disease type 1 1 | 171
Gout 1 | 93
Heart conduction disease 1 | 65
Infertility 1 | 163
Kidney Diseases 1 | 86
Leukopenia 1 | 42
Liver neoplasms 1 | 109
Lung Neoplasms 1 | 171
Malignant neoplasm of urinary bladder 1 | 16
Mammary Neoplasms 1 | 410
Microcephaly 1 | 149
Muscle Weakness 1 | 92
Neurodegenerative disease 1 | 383
Parkinson's disease 1 | 364
Quadriplegia 1 | 14
Thrombocytopenia 1 | 105
Tinea pedis 1 | 30
Urinary bladder cancer 1 | 31
sarcoidosis 1 | 358

Tissue

Blood and immune system 36 | 17,995
Female tissues 36 | 18,647
Male tissues 36 | 17,969
Nervous System 36 | 18,561
Digestive Tract 35 | 18,473
Endocrine System 35 | 18,512
Liver and Pancreas 35 | 18,136
Urinary Tract 35 | 18,444
Cardiovascular System 34 | 17,958
Skin and soft tissues 34 | 18,115
Respiratory system 33 | 17,484

Target Family

Non-IDG 20 | 11,971
Enzyme 9 | 4,146
Kinase 4 | 634
Transcription Factor 2 | 1,400
Ion Channel 1 | 341

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Transcriptional regulator ERG ERG Tchem Transcription Factor -2.49936 317.4 284
Cyclin-dependent kinase inhibitor 1 CDKN1A Tbio Enzyme -3.43357 2997.4 1177
Polycomb group RING finger protein 2 PCGF2 Tbio Non-IDG -1.55007 40.7 161
Integral membrane protein DGCR2/IDD DGCR2 Tbio Non-IDG -0.84089 6.77 108
Meiotic recombination protein SPO11 SPO11 Tbio Non-IDG -2.30956 203.0 132
E3 ubiquitin-protein ligase Praja-2 PJA2 Tbio Enzyme -0.52612 2.59 159
AP-4 complex subunit epsilon-1 AP4E1 Tdark Non-IDG -0.63202 4.65 21
Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase-like protein MGAT4D MGAT4D Tdark Enzyme -0.05115 0.76 45
Prostate stem cell antigen PSCA Tbio Non-IDG -2.34675 257.9 258
BTB/POZ domain-containing protein 16 BTBD16 Tbio Non-IDG 0.14 0.32 57