Development Level

Tbio 3 | 11,445

IMPC Phenotype

abnormal social-conspecific in... 3 | 3
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

Astrocytoma, Pilocytic 2 | 3,081
Breast cancer 2 | 3,578
Carcinoma 2 | 11,493
Depressive disorder 2 | 409
Schizophrenia 2 | 1,160
adult high grade glioma 2 | 3,801
astrocytic glioma 2 | 2,597
atypical teratoid / rhabdoid tumor 2 | 5,112
ependymoma 2 | 4,679
glioblastoma 2 | 5,792
lung cancer 2 | 4,740
medulloblastoma, large-cell 2 | 6,241
oligodendroglioma 2 | 2,850
osteosarcoma 2 | 7,950
psoriasis 2 | 6,694
Abnormally small eyeball 1 | 97
Abortion, Spontaneous 1 | 109
Alcoholic Intoxication, Chronic 1 | 289
Alzheimer's disease 1 | 658
Anemia 1 | 365
Anhedonia 1 | 27
Anterior segment mesenchymal dysgenesis 1 | 7
Bipolar Disorder 1 | 666
CATARACT 16, MULTIPLE TYPES 1 | 15
CATARACT, POSTERIOR POLAR, 4 (disorder) 1 | 1
Cancer 1 | 2,499
Cataract 1 | 297
Cataract 11, Multiple Types 1 | 1
Cataract, posterior polar, 4 1 | 1
Chronic NK-cell lymphocytosis 1 | 6
Cloudy cornea 1 | 33
Cocaine abuse 1 | 19
Corneal stromal opacities 1 | 33
Decreased size of eyeball 1 | 97
Depression, Bipolar 1 | 12
Down syndrome 1 | 499
Fibromyalgia 1 | 19
Glaucoma 1 | 239
Hemophagocytic lymphohistiocytosis 1 | 30
Hepatitis C 1 | 94
Human immunodeficiency virus infectious disease 1 | 138
Hypersensitivity reaction type II disease 1 | 253
Leber congenital amaurosis 1 | 69
Lens Opacities 1 | 231
Lethal midline granuloma 1 | 6
Leukopenia 1 | 72
Liver cancer 1 | 604
Liver disease 1 | 237
Lymphoproliferative syndrome 1 | 58
Major Depressive Disorder 1 | 301
Marijuana Abuse 1 | 31
Mental Depression 1 | 333
Metanephric adenoma 1 | 9
Microphthalmia 1 | 76
Microphthalmos 1 | 100
Mood Disorders 1 | 184
Multiple Sclerosis 1 | 540
Neoplasm Invasiveness 1 | 161
Neoplasm Recurrence, Local 1 | 37
Neurologic Manifestations 1 | 4
Niemann-Pick disease 1 | 14
Parkinson's disease 1 | 392
Peters anomaly 1 | 16
Prostatic Neoplasms 1 | 495
Rheumatoid arthritis 1 | 1,191
Skin disease 1 | 66
Spontaneous abortion 1 | 113
Thrombocytopenia 1 | 197
Tinea capitis 1 | 14
Unipolar Depression 1 | 250
active Crohn's disease 1 | 922
colon cancer 1 | 1,478
ductal carcinoma in situ 1 | 1,745
gastric cancer 1 | 459
group 3 medulloblastoma 1 | 4,104
interstitial lung disease 1 | 298
intraductal papillary-mucinous adenoma (IPMA) 1 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 1 | 3,291
invasive ductal carcinoma 1 | 2,951
lung carcinoma 1 | 2,843
malignant mesothelioma 1 | 3,232
ovarian cancer 1 | 8,520
pituitary cancer 1 | 1,972
primitive neuroectodermal tumor 1 | 3,035
subependymal giant cell astrocytoma 1 | 2,287
tuberculosis 1 | 2,010
type I diabetes mellitus 1 | 22

Tissue

Digestive Tract 3 | 17,369
Endocrine System 3 | 18,159
Male tissues 3 | 17,142
Skin and soft tissues 3 | 17,230
Blood and immune system 2 | 16,909
Cardiovascular System 2 | 15,192
Female tissues 2 | 17,400
Liver and Pancreas 2 | 16,750
Nervous System 2 | 16,725
Respiratory system 2 | 16,393
Urinary Tract 2 | 16,678

Target Family

Transcription Factor 2 | 1,400
Non-IDG 1 | 12,091

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Pituitary homeobox 3 PITX3 Tbio Transcription Factor -2.26232 188.5 134
E3 SUMO-protein ligase PIAS2 PIAS2 Tbio Transcription Factor -1.84354 65.2 389
Neural cell adhesion molecule 1 NCAM1 Tbio Non-IDG -3.58910 3930.7 1982