Development Level

Tbio 16 | 11,445
Tdark 6 | 6,588
Tchem 2 | 1,598
Tclin 1 | 613

Collection

GPCR: IDG Consortium (Targets) 2 | 126

IMPC Phenotype

abnormal skin coloration 25 | 25
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

Carcinoma 18 | 11,493
osteosarcoma 15 | 7,950
ovarian cancer 13 | 8,520
glioblastoma 11 | 5,792
atypical teratoid / rhabdoid tumor 9 | 5,112
ependymoma 8 | 4,679
psoriasis 8 | 6,694
lung cancer 7 | 4,740
group 3 medulloblastoma 6 | 4,104
medulloblastoma, large-cell 6 | 6,241
Pick disease 5 | 1,894
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
non-small cell lung cancer 5 | 2,890
primitive neuroectodermal tumor 5 | 3,035
Breast cancer 4 | 3,578
Cancer 4 | 2,499
Multiple myeloma 4 | 1,332
adult high grade glioma 4 | 3,801
breast carcinoma 4 | 1,638
ductal carcinoma in situ 4 | 1,745
invasive ductal carcinoma 4 | 2,951
lung adenocarcinoma 4 | 2,716
lung carcinoma 4 | 2,843
pancreatic cancer 4 | 2,398
primary pancreatic ductal adenocarcinoma 4 | 1,109
subependymal giant cell astrocytoma 4 | 2,287
ulcerative colitis 4 | 1,819
acute quadriplegic myopathy 3 | 1,158
astrocytic glioma 3 | 2,597
astrocytoma 3 | 1,146
gastric carcinoma 3 | 807
interstitial cystitis 3 | 2,312
malignant mesothelioma 3 | 3,232
oligodendroglioma 3 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
pediatric high grade glioma 3 | 1,064
pituitary cancer 3 | 1,972
Abortion, Spontaneous 2 | 109
Astrocytoma, Pilocytic 2 | 3,081
Kidney cancer 2 | 2,613
Liver Cirrhosis, Experimental 2 | 769
Obesity 2 | 678
Spontaneous abortion 2 | 113
acute myeloid leukemia 2 | 783
dermatomyositis 2 | 966
group 4 medulloblastoma 2 | 1,855
juvenile dermatomyositis 2 | 1,187
progressive supranuclear palsy 2 | 676
sonic hedgehog group medulloblastoma 2 | 467
tuberculosis and treatment for 6 months 2 | 409
Alzheimer's disease 1 | 658
Amyotrophic lateral sclerosis 1 | 451
Atopic dermatitis 1 | 952
Blepharophimosis 1 | 70
Byzanthine arch palate 1 | 194
Cannabis abuse 1 | 6
Cerebral atrophy 1 | 178
Chronic obstructive pulmonary disease 1 | 184
Clenched hands 1 | 6
Congenital disorder of glycosylation 1 | 54
Decreased antibody level in blood 1 | 35
Degenerative brain disorder 1 | 100
Dermatitis, Contact 1 | 71
Epilepsy 1 | 792
Erythromelalgia 1 | 7
Failure to gain weight 1 | 365
Focal glomerulosclerosis 1 | 37
Glomerulosclerosis, Focal Segmental 1 | 28
Hepatitis B 1 | 108
Hepatomegaly 1 | 285
Hypogammaglobulinemia 1 | 35
Hypoplasia of corpus callosum 1 | 90
Liver Failure 1 | 73
Liver cancer 1 | 604
Multiple Sclerosis 1 | 540
Overlapping fingers 1 | 10
Parkinson's disease 1 | 392
Pediatric failure to thrive 1 | 365
Prenatal onset 1 | 139
Respiratory Depression 1 | 10
Seizures 1 | 596
Sensorineural Hearing Loss (disorder) 1 | 284
Short palpebral fissure 1 | 38
Sporotrichosis 1 | 10
Varying degree of multiple fractures 1 | 53
Waldenstrons macroglobulinemia 1 | 765
Wide nose 1 | 35
X-linked cerebral adrenoleukodystrophy 1 | 116
adrenocortical carcinoma 1 | 1,428
autosomal dominant Emery-Dreifuss muscular dystrophy 1 | 510
colon cancer 1 | 1,478
cystic fibrosis 1 | 1,696
fibroadenoma 1 | 559
head and neck cancer 1 | 271
hereditary spastic paraplegia 1 | 318
medulloblastoma 1 | 720
tuberculosis 1 | 2,010
tuberculosis and treatment for 3 months 1 | 179

Tissue

Blood and immune system 25 | 16,909
Digestive Tract 25 | 17,369
Endocrine System 25 | 18,159
Nervous System 25 | 16,725
Respiratory system 25 | 16,393
Female tissues 24 | 17,400
Liver and Pancreas 24 | 16,750
Male tissues 24 | 17,142
Skin and soft tissues 24 | 17,230
Urinary Tract 24 | 16,678
Cardiovascular System 23 | 15,192

Target Family

Non-IDG 13 | 12,091
Enzyme 8 | 4,145
GPCR 3 | 408
Transcription Factor 1 | 1,400

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
CTD small phosphatase-like protein 2 CTDSPL2 Tdark Enzyme -0.57403 3.70 102
Kinesin-like protein KIF2C KIF2C Tbio Non-IDG -2.12404 136.3 256
Formin-like protein 3 FMNL3 Tbio Non-IDG -1.05785 13.4 42
Matrix metalloproteinase-15 MMP15 Tchem Enzyme -1.69065 43.4 351
Cytochrome c oxidase subunit 7C, mitochondrial COX7C Tdark Enzyme -1.02783 10.1 39
Stromelysin-3 MMP11 Tchem Non-IDG -2.72089 515.7 385
Anaphase-promoting complex subunit 15 ANAPC15 Tdark Enzyme -0.41378 2.22 27
Forkhead box protein J3 FOXJ3 Tbio Transcription Factor -0.86087 6.67 147
BTB/POZ domain-containing protein 16 BTBD16 Tbio Non-IDG 0.14 0.32 68
Myosin-10 MYH10 Tbio Non-IDG -1.77478 55.4 94