Development Level

Tbio 85 | 11,445
Tchem 14 | 1,598
Tdark 10 | 6,588
Tclin 5 | 613

Collection

GPCR: IDG Consortium (Targets) 1 | 126
Ion Channel: IDG Consortium (T... 1 | 99
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

abnormal seminal vesicle morph... 114 | 114
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

Carcinoma 64 | 11,493
ovarian cancer 61 | 8,520
osteosarcoma 53 | 7,950
medulloblastoma, large-cell 42 | 6,241
psoriasis 40 | 6,694
glioblastoma 33 | 5,792
intraductal papillary-mucinous neoplasm (IPMN) 32 | 3,291
atypical teratoid / rhabdoid tumor 31 | 5,112
Breast cancer 28 | 3,578
ependymoma 28 | 4,679
lung cancer 27 | 4,740
adult high grade glioma 26 | 3,801
group 3 medulloblastoma 25 | 4,104
oligodendroglioma 25 | 2,850
interstitial cystitis 23 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 23 | 2,955
malignant mesothelioma 22 | 3,232
non-small cell lung cancer 22 | 2,890
pancreatic cancer 22 | 2,398
Cancer 21 | 2,499
invasive ductal carcinoma 21 | 2,951
lung adenocarcinoma 21 | 2,716
astrocytic glioma 19 | 2,597
intraductal papillary-mucinous carcinoma (IPMC) 19 | 2,989
pituitary cancer 19 | 1,972
Astrocytoma, Pilocytic 18 | 3,081
lung carcinoma 18 | 2,843
primitive neuroectodermal tumor 18 | 3,035
tuberculosis 18 | 2,010
Autosomal recessive predisposition 16 | 1,442
ulcerative colitis 16 | 1,819
diabetes mellitus 15 | 1,728
pancreatic ductal adenocarcinoma liver metastasis 15 | 1,962
adrenocortical carcinoma 14 | 1,428
ductal carcinoma in situ 14 | 1,745
Kidney cancer 13 | 2,613
Rheumatoid arthritis 13 | 1,191
Schizophrenia 12 | 1,160
colon cancer 12 | 1,478
subependymal giant cell astrocytoma 12 | 2,287
Obesity 11 | 678
cystic fibrosis 11 | 1,696
group 4 medulloblastoma 11 | 1,855
Pick disease 10 | 1,894
cutaneous lupus erythematosus 10 | 1,057
spina bifida 10 | 1,074
breast carcinoma 9 | 1,638
pancreatic carcinoma 9 | 562
Alzheimer's disease 8 | 658
Bipolar Disorder 8 | 666
Liver Cirrhosis, Experimental 8 | 769
Melanoma 8 | 711
acute quadriplegic myopathy 8 | 1,158
primary Sjogren syndrome 8 | 735
Asthma 7 | 385
Atherosclerosis 7 | 291
Atopic dermatitis 7 | 952
Multiple Sclerosis 7 | 540
Neurodegenerative disease 7 | 414
chronic rhinosinusitis 7 | 512
juvenile dermatomyositis 7 | 1,187
primary pancreatic ductal adenocarcinoma 7 | 1,109
Acquired metabolic disease 6 | 336
Coronary artery disease 6 | 268
Prostatic Neoplasms 6 | 495
astrocytoma 6 | 1,146
gastric cancer 6 | 459
hepatocellular carcinoma 6 | 547
Multiple myeloma 5 | 1,332
Short stature 5 | 531
Stomach Neoplasms 5 | 300
Type 2 diabetes mellitus 5 | 272
Arthritis, Rheumatoid 4 | 174
Diarrhea 4 | 253
Duchenne muscular dystrophy 4 | 601
Epilepsy 4 | 792
Heart disease 4 | 306
Hypersensitivity reaction type II disease 4 | 253
Hypertension 4 | 396
Hypoplastic mandible condyle 4 | 275
Infantile onset 4 | 238
Kidney disease 4 | 430
Liver cancer 4 | 604
Lung Neoplasms 4 | 232
Mandibular hypoplasia 4 | 275
Micrognathism 4 | 275
Neuropathy 4 | 261
Osteoporosis 4 | 363
Pancreatitis 4 | 123
Small head 4 | 374
Systemic lupus erythematosus 4 | 194
active Crohn's disease 4 | 922
acute myeloid leukemia 4 | 783
inflammatory breast cancer 4 | 286
mucosa-associated lymphoid tissue lymphoma 4 | 484
nasopharyngeal carcinoma 4 | 1,058
pediatric high grade glioma 4 | 1,064
posterior fossa group A ependymoma 4 | 468
sarcoidosis 4 | 370
sonic hedgehog group medulloblastoma 4 | 467

Tissue

Endocrine System 112 | 18,159
Female tissues 109 | 17,400
Digestive Tract 108 | 17,369
Male tissues 107 | 17,142
Skin and soft tissues 107 | 17,230
Nervous System 106 | 16,725
Blood and immune system 105 | 16,909
Liver and Pancreas 104 | 16,750
Respiratory system 104 | 16,393
Urinary Tract 104 | 16,678
Cardiovascular System 99 | 15,192

Target Family

Non-IDG 53 | 12,091
Enzyme 32 | 4,145
Transcription Factor 7 | 1,400
Kinase 5 | 634
Epigenetic 4 | 242
GPCR 4 | 408
Transporter 4 | 473
Ion Channel 3 | 344
Nuclear Receptor 2 | 48

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
POU domain, class 2, transcription factor 3 POU2F3 Tbio Transcription Factor -2.50813 322.4 96
Interleukin-18-binding protein IL18BP Tbio Non-IDG -2.00596 101.6 307
Caskin-1 CASKIN1 Tdark Non-IDG -0.63111 5.31 22
SLIT and NTRK-like protein 1 SLITRK1 Tbio Non-IDG -2.74906 555.5 206
Spexin SPX Tbio Non-IDG -2.81062 637.9 19
LHFPL tetraspan subfamily member 1 protein LHFPL1 Tdark Non-IDG 0.00000 1.00 69
Four-jointed box protein 1 FJX1 Tbio Non-IDG -0.93089 9.00 65
Small kinetochore-associated protein KNSTRN Tbio Non-IDG -1.28291 21.4 32
Uridine diphosphate glucose pyrophosphatase NUDT14 Tdark Enzyme -0.67608 5.47 45
Tyrosine-protein kinase TXK TXK Tchem Kinase -2.28365 191.1 194