Development Level

Tbio 29 | 10,625
Tdark 9 | 7,003
Tchem 6 | 1,890
Tclin 3 | 602

Collection

Kinase: IDG Consortium (Targets) 1 | 125

IMPC Phenotype

abnormal seminal vesicle morph... 47 | 47
preweaning lethality, complete... 633 | 633
preweaning lethality, incomple... 260 | 260
abnormal behavior 226 | 226
decreased lean body mass 195 | 195
embryonic lethality prior to t... 187 | 187
decreased total body fat amoun... 186 | 186
decreased body weight 174 | 174
decreased bone mineral content 157 | 157
embryonic lethality prior to o... 148 | 148
abnormal bone structure 131 | 131
increased or absent threshold ... 128 | 128
decreased bone mineral density 126 | 126
decreased grip strength 123 | 123
decreased circulating glucose ... 121 | 121
increased circulating alkaline... 119 | 119
abnormal embryo size 112 | 112
enlarged heart 111 | 111
decreased body length 108 | 108
hyperactivity 108 | 108
increased lean body mass 107 | 107
abnormal retina morphology 100 | 100
increased mean corpuscular hem... 93 | 93
increased bone mineral content 92 | 92
increased mean corpuscular vol... 91 | 91
hypoactivity 89 | 89
decreased circulating choleste... 85 | 85
decreased circulating triglyce... 83 | 83
increased grip strength 83 | 83
short tibia 82 | 82
decreased circulating serum al... 79 | 79
decreased circulating HDL chol... 77 | 77
decreased circulating insulin ... 75 | 75
abnormal lens morphology 73 | 73
increased circulating sodium l... 71 | 71
increased fasted circulating g... 68 | 68
prenatal lethality prior to he... 64 | 64
abnormal sleep behavior 63 | 63
increased circulating HDL chol... 63 | 63
decreased lumbar vertebrae num... 62 | 62
increased sacral vertebrae num... 62 | 62
male infertility 62 | 62
abnormal retinal pigmentation 61 | 61
decreased rib number 59 | 59
increased total body fat amoun... 57 | 57
improved glucose tolerance 56 | 56
increased exploration in new e... 56 | 56
abnormal bone mineralization 55 | 55
abnormal coat-hair pigmentatio... 54 | 54
decreased leukocyte cell numbe... 54 | 54
decreased circulating alanine ... 53 | 53
decreased hemoglobin content 53 | 53
increased circulating choleste... 53 | 53
abnormal behavioral response t... 52 | 52
decreased prepulse inhibition 52 | 52
impaired glucose tolerance 52 | 52
increased bone mineral density 52 | 52
abnormal gait 51 | 51
abnormal heart morphology 51 | 51
decreased mean corpuscular vol... 50 | 50
decreased caudal vertebrae num... 49 | 49
decreased fasted circulating g... 49 | 49
decreased startle reflex 48 | 48
thrombocytopenia 46 | 46
increased hemoglobin content 45 | 45
decreased heart weight 44 | 44
increased blood urea nitrogen ... 44 | 44
decreased erythrocyte cell num... 43 | 43
increased circulating chloride... 43 | 43
increased body weight 42 | 42
decreased circulating alkaline... 41 | 41
decreased circulating total pr... 41 | 41
decreased eosinophil cell numb... 41 | 41
increased rib number 41 | 41
decreased circulating free fat... 39 | 39
abnormal eye morphology 38 | 38
increased startle reflex 38 | 38
abnormal neural tube closure 37 | 37
decreased circulating LDL chol... 37 | 37
decreased neutrophil cell numb... 37 | 37
increased heart weight 37 | 37
increased leukocyte cell numbe... 37 | 37
small testis 37 | 37
abnormal spleen morphology 36 | 36
increased hematocrit 36 | 36
cardiovascular system phenotyp... 35 | 35
limb grasping 35 | 35
decreased mean corpuscular hem... 34 | 34
female infertility 34 | 34
tremors 34 | 34
decreased circulating calcium ... 33 | 33
abnormal cranium morphology 32 | 32
decreased circulating chloride... 32 | 32
decreased threshold for audito... 32 | 32
increased circulating calcium ... 32 | 32
abnormal epididymis morphology 31 | 31
decreased T cell number 31 | 31
decreased blood urea nitrogen ... 31 | 31
decreased circulating fructosa... 31 | 31
increased circulating potassiu... 31 | 31

Disease

ovarian cancer 24 | 8,491
psoriasis 20 | 6,685
medulloblastoma, large-cell 17 | 6,234
osteosarcoma 15 | 7,933
interstitial cystitis 13 | 2,299
glioblastoma 11 | 5,572
intraductal papillary-mucinous neoplasm (IPMN) 10 | 3,289
lung cancer 10 | 4,473
Breast cancer 9 | 3,098
oligodendroglioma 9 | 2,849
ulcerative colitis 9 | 2,087
Rheumatoid Arthritis 8 | 1,170
adult high grade glioma 8 | 2,148
pancreatic cancer 8 | 2,300
pituitary cancer 8 | 1,972
astrocytic glioma 7 | 2,241
atypical teratoid / rhabdoid tumor 7 | 4,369
group 4 medulloblastoma 7 | 1,875
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,956
lung adenocarcinoma 7 | 2,714
non-small cell lung cancer 7 | 2,798
primitive neuroectodermal tumor 7 | 3,031
Carcinoma 6 | 2,147
adrenocortical carcinoma 6 | 1,427
diabetes mellitus 6 | 1,663
pilocytic astrocytoma 6 | 3,086
breast carcinoma 5 | 1,614
colon cancer 5 | 1,475
cystic fibrosis 5 | 1,670
ependymoma 5 | 2,514
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,988
invasive ductal carcinoma 5 | 2,950
lung carcinoma 5 | 2,844
malignant mesothelioma 5 | 3,163
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,795
posterior fossa group A ependymoma 5 | 1,511
Alzheimer's disease 4 | 644
Cancer 4 | 2,346
Obesity 4 | 616
atypical teratoid/rhabdoid tumor 4 | 1,095
ductal carcinoma in situ 4 | 1,745
primary pancreatic ductal adenocarcinoma 4 | 1,271
spina bifida 4 | 1,064
tuberculosis 4 | 1,563
Atopic dermatitis 3 | 944
Diarrhea 3 | 155
Prostatic Neoplasms 3 | 471
astrocytoma 3 | 1,493
group 3 medulloblastoma 3 | 2,254
medulloblastoma 3 | 1,524
non primary Sjogren syndrome sicca 3 | 840
non-inflammatory breast cancer 3 | 208
pediatric high grade glioma 3 | 2,712
subependymal giant cell astrocytoma 3 | 2,287
Acquired metabolic disease 2 | 267
Amenorrhea 2 | 60
Arsenic Poisoning 2 | 59
Blastic phase chronic myeloid leukemia 2 | 58
Chronic Myelocytic Leukemia Accelerated Phase 2 | 59
Chronic phase chronic myeloid leukemia 2 | 45
Colorectal Neoplasms 2 | 217
Coronary artery disease 2 | 240
Dental enamel hypoplasia 2 | 12
Dermatologic disorders 2 | 65
Idiopathic Membranous Glomerulonephritis 2 | 18
Infertility 2 | 163
Kawasaki disease 2 | 24
Mantle cell lymphoma 2 | 20
Multiple myeloma 2 | 1,327
Philadelphia Chromosome Positive Chronic Myelocytic Leukemia 2 | 45
Philadelphia chromosome-positive acute lymphoblastic leukemia 2 | 47
Pick disease 2 | 1,893
Rickets 2 | 42
Squamous cell carcinoma 2 | 96
Stomach Neoplasms 2 | 282
Thrombophilia 2 | 37
Tooth agenesis 2 | 38
Type 1 diabetes mellitus 2 | 104
Type 2 diabetes mellitus 2 | 192
active Crohn's disease 2 | 918
acute myeloid leukemia 2 | 785
acute quadriplegic myopathy 2 | 1,157
chronic rhinosinusitis 2 | 512
cutaneous lupus erythematosus 2 | 1,056
fibroadenoma 2 | 557
gastric carcinoma 2 | 832
glioblastoma multiforme 2 | 347
head and neck cancer 2 | 270
interstitial lung disease 2 | 292
mucosa-associated lymphoid tissue lymphoma 2 | 480
pancreatic carcinoma 2 | 567
posterior fossa group B ependymoma 2 | 1,530
primary Sjogren syndrome 2 | 788
Atypical autism 1 | 25
Chronic eosinophilic leukemia 1 | 11
Febrile Convulsions 1 | 11
Idiopathic hypereosinophilic syndrome 1 | 10
Larsen syndrome 1 | 11
Myelodysplastic/ Myeloproliferative Diseases associated with Platelet-derived Growth Factor Receptor 1 | 9
Systemic mast cell disease 1 | 12

Tissue

Nervous System 47 | 18,560
Digestive Tract 46 | 18,472
Endocrine System 46 | 18,511
Female tissues 46 | 18,646
Liver and Pancreas 46 | 18,135
Male tissues 46 | 17,968
Urinary Tract 46 | 18,443
Blood and immune system 45 | 17,994
Cardiovascular System 45 | 17,957
Respiratory system 44 | 17,483
Skin and soft tissues 44 | 18,114

Target Family

Non-IDG 21 | 11,969
Enzyme 14 | 4,146
Kinase 4 | 634
Epigenetic 2 | 242
GPCR 2 | 408
Transcription Factor 2 | 1,400
Ion Channel 1 | 341
Transporter 1 | 473

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
CMRF35-like molecule 2 CD300E Tbio Non-IDG -0.85912 7.41 123
Adipogenin ADIG Tdark Non-IDG -1.22875 16.0 3
Testis development-related protein TDRP Tbio Non-IDG -0.62632 5.48 36
Transcription factor GATA-5 GATA5 Tbio Transcription Factor -1.94419 83.7 166
Dentin sialophosphoprotein DSPP Tbio Non-IDG -2.84705 679.6 48
Tumor necrosis factor receptor superfamily member EDAR EDAR Tbio Non-IDG -2.18073 151.1 144
Serine/threonine-protein kinase RIO2 RIOK2 Tbio Kinase -1.09750 13.3 160
Protein cereblon CRBN Tclin Non-IDG -2.27068 187.1 69
Ephrin type-A receptor 6 EPHA6 Tchem Kinase -1.33373 29.2 223
CD83 antigen CD83 Tbio Non-IDG -2.81895 610.6 496