Development Level

Tbio 20 | 11,445
Tchem 5 | 1,598
Tclin 1 | 613
Tdark 1 | 6,588

IMPC Phenotype

abnormal retinal vasculature m... 27 | 27
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

ovarian cancer 20 | 8,520
Carcinoma 17 | 11,493
medulloblastoma, large-cell 17 | 6,241
osteosarcoma 17 | 7,950
glioblastoma 12 | 5,792
intraductal papillary-mucinous neoplasm (IPMN) 12 | 3,291
atypical teratoid / rhabdoid tumor 11 | 5,112
ependymoma 11 | 4,679
lung cancer 11 | 4,740
group 3 medulloblastoma 8 | 4,104
psoriasis 8 | 6,694
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,989
invasive ductal carcinoma 7 | 2,951
primitive neuroectodermal tumor 7 | 3,035
Autosomal recessive predisposition 6 | 1,442
Breast cancer 6 | 3,578
Intellectual disability 6 | 1,016
pediatric high grade glioma 6 | 1,064
Cancer 5 | 2,499
Dull intelligence 5 | 645
Low intelligence 5 | 645
Mental Retardation 5 | 645
Mental deficiency 5 | 645
Poor school performance 5 | 645
adult high grade glioma 5 | 3,801
colon cancer 5 | 1,478
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
malignant mesothelioma 5 | 3,232
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
group 4 medulloblastoma 4 | 1,855
interstitial cystitis 4 | 2,312
lung adenocarcinoma 4 | 2,716
oligodendroglioma 4 | 2,850
subependymal giant cell astrocytoma 4 | 2,287
Atopic dermatitis 3 | 952
Autistic Disorder 3 | 364
Big calvaria 3 | 147
Dental caries 3 | 164
Epilepsy 3 | 792
Increased head circumference 3 | 147
Increased size of cranium 3 | 147
Increased size of skull 3 | 147
Kidney cancer 3 | 2,613
Obesity 3 | 678
Pick disease 3 | 1,894
Prenatal onset 3 | 139
Rheumatoid arthritis 3 | 1,191
Seizures 3 | 596
Short stature 3 | 531
acute myeloid leukemia 3 | 783
astrocytic glioma 3 | 2,597
diabetes mellitus 3 | 1,728
ductal carcinoma in situ 3 | 1,745
hepatocellular carcinoma 3 | 547
lung carcinoma 3 | 2,843
medulloblastoma 3 | 720
nephrosclerosis 3 | 333
non-small cell lung cancer 3 | 2,890
progressive supranuclear palsy 3 | 676
ulcerative colitis 3 | 1,819
Alzheimer's disease 2 | 658
Anteverted nostril 2 | 191
Astrocytoma, Pilocytic 2 | 3,081
Cognitive delay 2 | 608
Concave bridge of nose 2 | 195
Congenital Bilateral Cataracts 2 | 50
Congenital anomaly of face 2 | 56
Congenital cataract 2 | 50
Delayed speech and language development 2 | 112
Depressed nasal bridge 2 | 195
Depressed nasal root/bridge 2 | 195
Distortion of face 2 | 46
Dysmorphic facies 2 | 46
Funny looking face 2 | 46
Global developmental delay 2 | 608
Hepatomegaly 2 | 285
Hypoglycemia 2 | 152
Language Delay 2 | 112
Mental and motor retardation 2 | 608
Schizophrenia 2 | 1,160
Short nose 2 | 132
Small nose 2 | 132
Speech Delay 2 | 112
Speech impairment 2 | 112
Telecanthus 2 | 62
Vomiting 2 | 116
active ulcerative colitis 2 | 764
acute quadriplegic myopathy 2 | 1,158
adrenocortical carcinoma 2 | 1,428
astrocytoma 2 | 1,146
breast carcinoma 2 | 1,638
cutaneous lupus erythematosus 2 | 1,057
cystic fibrosis 2 | 1,696
esophageal adenocarcinoma 2 | 737
facial deformity 2 | 46
gastric cancer 2 | 459
juvenile dermatomyositis 2 | 1,187
pancreatic cancer 2 | 2,398
pituitary cancer 2 | 1,972
tuberculosis 2 | 2,010

Tissue

Blood and immune system 26 | 16,909
Digestive Tract 26 | 17,369
Endocrine System 26 | 18,159
Female tissues 26 | 17,400
Liver and Pancreas 26 | 16,750
Male tissues 26 | 17,142
Nervous System 26 | 16,725
Respiratory system 26 | 16,393
Skin and soft tissues 26 | 17,230
Urinary Tract 26 | 16,678
Cardiovascular System 25 | 15,192

Target Family

Enzyme 13 | 4,145
Non-IDG 9 | 12,091
Epigenetic 2 | 242
Kinase 1 | 634
Nuclear Receptor 1 | 48
Transcription Factor 1 | 1,400

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
von Willebrand factor A domain-containing protein 8 VWA8 Tbio Non-IDG -0.36798 2.42 8
Corneodesmosin CDSN Tbio Non-IDG -3.23661 1709.5 0
Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial ETFDH Tbio Enzyme -1.77891 60.9 204
Lanosterol synthase LSS Tchem Enzyme -2.22381 150.1 87
Rho GTPase-activating protein 33 ARHGAP33 Tbio Enzyme -0.79198 7.42 114
Multiple PDZ domain protein MPDZ Tbio Non-IDG -1.63690 47.3 58
Amiloride-sensitive amine oxidase [copper-containing] AOC1 Tchem Enzyme -2.77629 590.0 271
Adenylosuccinate lyase ADSL Tbio Enzyme -3.32293 2023.8 144
Hepatocyte nuclear factor 4-alpha HNF4A Tchem Nuclear Receptor -3.19918 1373.3 664
Histone deacetylase 1 HDAC1 Tclin Epigenetic -3.03775 954.3 1201