Development Level

Tbio 18 | 11,445
Tchem 4 | 1,598
Tclin 2 | 613
Tdark 2 | 6,588

IMPC Phenotype

abnormal retinal blood vessel ... 26 | 26
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

ovarian cancer 20 | 8,520
Carcinoma 18 | 11,493
osteosarcoma 15 | 7,950
atypical teratoid / rhabdoid tumor 13 | 5,112
glioblastoma 13 | 5,792
medulloblastoma, large-cell 12 | 6,241
ependymoma 11 | 4,679
lung cancer 10 | 4,740
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,291
primitive neuroectodermal tumor 9 | 3,035
invasive ductal carcinoma 8 | 2,951
Breast cancer 7 | 3,578
adult high grade glioma 7 | 3,801
group 4 medulloblastoma 7 | 1,855
pediatric high grade glioma 7 | 1,064
psoriasis 7 | 6,694
Pick disease 6 | 1,894
lung carcinoma 6 | 2,843
oligodendroglioma 6 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
Astrocytoma, Pilocytic 5 | 3,081
astrocytic glioma 5 | 2,597
ductal carcinoma in situ 5 | 1,745
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
lung adenocarcinoma 5 | 2,716
Autosomal recessive predisposition 4 | 1,442
Cancer 4 | 2,499
Intellectual disability 4 | 1,016
group 3 medulloblastoma 4 | 4,104
malignant mesothelioma 4 | 3,232
non primary Sjogren syndrome sicca 4 | 891
non-small cell lung cancer 4 | 2,890
pancreatic cancer 4 | 2,398
tuberculosis 4 | 2,010
Big calvaria 3 | 147
Dull intelligence 3 | 645
Increased head circumference 3 | 147
Increased size of cranium 3 | 147
Increased size of skull 3 | 147
Low intelligence 3 | 645
Mental Retardation 3 | 645
Mental deficiency 3 | 645
Poor school performance 3 | 645
Rheumatoid arthritis 3 | 1,191
Schizophrenia 3 | 1,160
astrocytoma 3 | 1,146
breast carcinoma 3 | 1,638
medulloblastoma 3 | 720
pituitary cancer 3 | 1,972
primary pancreatic ductal adenocarcinoma 3 | 1,109
subependymal giant cell astrocytoma 3 | 2,287
ulcerative colitis 3 | 1,819
Alzheimer's disease 2 | 658
Communicating Hydrocephalus 2 | 8
Concave bridge of nose 2 | 195
Congenital Bilateral Cataracts 2 | 50
Congenital cataract 2 | 50
Dental caries 2 | 164
Depressed nasal bridge 2 | 195
Depressed nasal root/bridge 2 | 195
Down syndrome 2 | 499
Epilepsy 2 | 792
Glycosuria 2 | 29
Hepatomegaly 2 | 285
Hypoglycemia 2 | 152
Kidney cancer 2 | 2,613
Multiple myeloma 2 | 1,332
Obesity 2 | 678
Orbital separation excessive 2 | 244
Prenatal onset 2 | 139
Seizures 2 | 596
Short stature 2 | 531
Stomach Neoplasms 2 | 300
Telecanthus 2 | 62
Vascular disease 2 | 319
Vomiting 2 | 116
active ulcerative colitis 2 | 764
acute myeloid leukemia 2 | 783
adrenocortical carcinoma 2 | 1,428
cutaneous lupus erythematosus 2 | 1,057
diabetes mellitus 2 | 1,728
fibroadenoma 2 | 559
hepatocellular carcinoma 2 | 547
posterior fossa group B ependymoma 2 | 416
progressive supranuclear palsy 2 | 676
spina bifida 2 | 1,074
Adult Fanconi syndrome 1 | 12
Alcohol Withdrawal Seizures 1 | 2
Colitis, Ulcerative 1 | 59
Coronal hypospadias 1 | 4
Dacryocystitis 1 | 11
Hyperphosphaturia 1 | 21
Mowat-Wilson syndrome 1 | 11
Ovarian serous carcinoma 1 | 5
Partial central choroid dystrophy 1 | 11
Partial duplication of thumb phalanx 1 | 6
Subcoronal hypospadias 1 | 4
Xerostomia 1 | 42
genital abnormal 1 | 17

Tissue

Blood and immune system 26 | 16,909
Cardiovascular System 26 | 15,192
Digestive Tract 26 | 17,369
Endocrine System 26 | 18,159
Female tissues 26 | 17,400
Liver and Pancreas 26 | 16,750
Male tissues 26 | 17,142
Nervous System 26 | 16,725
Respiratory system 26 | 16,393
Skin and soft tissues 26 | 17,230
Urinary Tract 26 | 16,678

Target Family

Non-IDG 12 | 12,091
Enzyme 7 | 4,145
Epigenetic 3 | 242
GPCR 1 | 408
Kinase 1 | 634
Nuclear Receptor 1 | 48
Transcription Factor 1 | 1,400

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cytochrome b561 CYB561 Tbio Non-IDG -1.41422 21.1 62
ER membrane protein complex subunit 8 EMC8 Tdark Non-IDG 0.06 0.41 160
Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein NOS1AP Tbio Enzyme -2.13262 142.6 159
E3 ubiquitin-protein ligase RNF38 RNF38 Tdark Enzyme -0.36486 2.96 75
Neurocalcin-delta NCALD Tbio Non-IDG -1.30940 20.7 102
Metalloproteinase inhibitor 3 TIMP3 Tbio Enzyme -2.76157 592.3 503
JmjC domain-containing protein 5 KDM8 Tbio Epigenetic -1.68201 49.6 209
Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial ETFDH Tbio Enzyme -1.77891 60.9 204
Lanosterol synthase LSS Tchem Enzyme -2.22381 150.1 87
Multiple PDZ domain protein MPDZ Tbio Non-IDG -1.63690 47.3 58