Development Level

Tbio 11 | 11,445
Tdark 4 | 6,588
Tchem 1 | 1,598
Tclin 1 | 613

IMPC Phenotype

abnormal response to tactile s... 17 | 17
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

Carcinoma 12 | 11,493
medulloblastoma, large-cell 9 | 6,241
ovarian cancer 8 | 8,520
atypical teratoid / rhabdoid tumor 7 | 5,112
ependymoma 7 | 4,679
glioblastoma 7 | 5,792
lung cancer 6 | 4,740
group 3 medulloblastoma 5 | 4,104
osteosarcoma 5 | 7,950
primitive neuroectodermal tumor 5 | 3,035
psoriasis 5 | 6,694
astrocytic glioma 4 | 2,597
breast carcinoma 4 | 1,638
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
non-small cell lung cancer 4 | 2,890
oligodendroglioma 4 | 2,850
Astrocytoma, Pilocytic 3 | 3,081
Breast cancer 3 | 3,578
Multiple myeloma 3 | 1,332
adult high grade glioma 3 | 3,801
ductal carcinoma in situ 3 | 1,745
invasive ductal carcinoma 3 | 2,951
malignant mesothelioma 3 | 3,232
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
pediatric high grade glioma 3 | 1,064
pituitary cancer 3 | 1,972
subependymal giant cell astrocytoma 3 | 2,287
Autosomal recessive predisposition 2 | 1,442
Colorectal Neoplasms 2 | 243
Liver Cirrhosis, Experimental 2 | 769
Muscle hypotonia 2 | 571
Pick disease 2 | 1,894
chronic rhinosinusitis 2 | 512
esophageal adenocarcinoma 2 | 737
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
lung adenocarcinoma 2 | 2,716
tuberculosis 2 | 2,010
Adrenoleukodystrophy 1 | 29
Alcohol dependence 1 | 107
Alcoholic Intoxication 1 | 34
Alcoholic Intoxication, Chronic 1 | 289
Alcoholism 1 | 45
Ambiguous Genitalia 1 | 24
Body dysmorphic disorder 1 | 11
Brain infarction 1 | 22
Cellulitis 1 | 20
Congenital clubfoot 1 | 109
Crohn Disease 1 | 45
Decreased adenosylcobalamin (AdoCbl) 1 | 3
Decreased platelet count 1 | 111
Esophageal Neoplasms 1 | 69
Esophageal Squamous Cell Carcinoma 1 | 77
Flushing 1 | 60
Gastrointestinal Stromal Tumors 1 | 48
Gastrointestinal stromal tumor 1 | 62
Growth delay 1 | 114
Growth failure 1 | 114
Growth retardation 1 | 115
Hamman-Rich syndrome 1 | 34
Heart Injuries 1 | 3
Heart conduction disease 1 | 83
Hernia, Inguinal 1 | 89
Heroin dependence 1 | 30
Homocystinuria 1 | 21
Hyperhomocystinemia 1 | 6
Hypokalemia 1 | 52
Intracranial aneurysm 1 | 24
Lethargy 1 | 77
Liver Cirrhosis 1 | 181
Liver disease 1 | 237
Lupus Erythematosus, Systemic 1 | 67
Methylmalonic aciduria 1 | 9
Mitral valve insufficiency 1 | 49
Neuronal ceroid lipofuscinosis 8 northern epilepsy variant 1 | 6
Neutrophil count decreased 1 | 47
Orofaciodigital syndrome 1 | 21
Osteochondrosis 1 | 17
Pancreatic Neuroendocrine Tumor 1 | 45
Peroxisomal disease 1 | 22
Poor growth 1 | 114
Precancerous Conditions 1 | 80
Prenatal onset 1 | 139
Renal Cell Carcinoma 1 | 214
Retinitis pigmentosa 4 1 | 38
Schnyder Corneal Dystrophy 1 | 23
Squamous cell carcinoma of esophagus 1 | 77
Succinic semialdehyde dehydrogenase deficiency 1 | 16
Thrombocytopenia 1 | 197
Vascular Diseases 1 | 16
Very poor growth 1 | 114
Visual epilepsy 1 | 4
Werner syndrome 1 | 29
Wernicke-Korsakoff syndrome 1 | 10
cystic fibrosis and chronic rhinosinusitis 1 | 214
esophageal cancer 1 | 22
inflammatory breast cancer 1 | 286
limb girdle muscular dystrophy 2B 1 | 40
non-inflammatory breast cancer 1 | 66
sarcoidosis 1 | 370

Tissue

Blood and immune system 17 | 16,909
Cardiovascular System 17 | 15,192
Digestive Tract 17 | 17,369
Endocrine System 17 | 18,159
Female tissues 17 | 17,400
Liver and Pancreas 17 | 16,750
Male tissues 17 | 17,142
Nervous System 17 | 16,725
Respiratory system 17 | 16,393
Skin and soft tissues 17 | 17,230
Urinary Tract 17 | 16,678

Target Family

Non-IDG 8 | 12,091
Enzyme 2 | 4,145
Kinase 2 | 634
Transporter 2 | 473
Epigenetic 1 | 242
Ion Channel 1 | 344
Transcription Factor 1 | 1,400

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Putative sodium-coupled neutral amino acid transporter 10 SLC38A10 Tdark Transporter -0.27712 1.71 25
B9 domain-containing protein 1 B9D1 Tdark Non-IDG -0.61316 3.72 43
ATPase WRNIP1 WRNIP1 Tbio Enzyme -2.55209 340.4 166
Syntaxin-8 STX8 Tbio Non-IDG -2.59234 391.5 134
Xylulose kinase XYLB Tbio Kinase -1.97293 93.1 74
JmjC domain-containing protein 5 KDM8 Tbio Epigenetic -1.68201 49.6 209
Dual specificity protein kinase CLK1 CLK1 Tchem Kinase -1.93720 87.9 156
Fibroblast growth factor 11 FGF11 Tbio Non-IDG -1.03057 9.36 139
Rho guanine nucleotide exchange factor 4 ARHGEF4 Tbio Non-IDG -1.40554 28.0 126
Protein FAM110B FAM110B Tdark Non-IDG -0.03110 1.29 47