Development Level

Tbio 19 | 11,445
Tdark 3 | 6,588
Tchem 2 | 1,598
Tclin 2 | 613

IMPC Phenotype

abnormal pericardium morpholog... 26 | 26
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

Carcinoma 22 | 11,493
ovarian cancer 15 | 8,520
medulloblastoma, large-cell 14 | 6,241
osteosarcoma 13 | 7,950
lung cancer 11 | 4,740
psoriasis 11 | 6,694
glioblastoma 10 | 5,792
atypical teratoid / rhabdoid tumor 8 | 5,112
ependymoma 8 | 4,679
malignant mesothelioma 8 | 3,232
Kidney cancer 7 | 2,613
adrenocortical carcinoma 7 | 1,428
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
Breast cancer 6 | 3,578
adult high grade glioma 6 | 3,801
astrocytic glioma 6 | 2,597
invasive ductal carcinoma 6 | 2,951
lung adenocarcinoma 6 | 2,716
lung carcinoma 6 | 2,843
oligodendroglioma 6 | 2,850
group 4 medulloblastoma 5 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
non-small cell lung cancer 5 | 2,890
Autosomal recessive predisposition 4 | 1,442
Cancer 4 | 2,499
group 3 medulloblastoma 4 | 4,104
juvenile dermatomyositis 4 | 1,187
pancreatic cancer 4 | 2,398
primary pancreatic ductal adenocarcinoma 4 | 1,109
primitive neuroectodermal tumor 4 | 3,035
spina bifida 4 | 1,074
ulcerative colitis 4 | 1,819
Astrocytoma, Pilocytic 3 | 3,081
Endometriosis 3 | 540
Liver cancer 3 | 604
breast carcinoma 3 | 1,638
cutaneous lupus erythematosus 3 | 1,057
diabetes mellitus 3 | 1,728
ductal carcinoma in situ 3 | 1,745
medulloblastoma 3 | 720
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
pediatric high grade glioma 3 | 1,064
pituitary cancer 3 | 1,972
tuberculosis 3 | 2,010
Alzheimer's disease 2 | 658
Dermatologic disorders 2 | 93
Duchenne muscular dystrophy 2 | 601
Dull intelligence 2 | 645
Epilepsy 2 | 792
Fetal Growth Retardation 2 | 189
Infant, Small for Gestational Age 2 | 176
Intellectual disability 2 | 1,016
Intrauterine retardation 2 | 176
Klippel-Trenaunay syndrome 2 | 13
Low intelligence 2 | 645
Melanoma 2 | 711
Mental Retardation 2 | 645
Mental deficiency 2 | 645
Multiple cutaneous and mucosal venous malformations 2 | 10
Multiple myeloma 2 | 1,332
Parkinson's disease 2 | 392
Poor school performance 2 | 645
Postnatal growth retardation 2 | 57
Schizophrenia 2 | 1,160
Seizures 2 | 596
Skin Abnormalities 2 | 37
Skin cancer 2 | 469
acute quadriplegic myopathy 2 | 1,158
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
colon cancer 2 | 1,478
cystic fibrosis 2 | 1,696
cystic fibrosis and chronic rhinosinusitis 2 | 214
fibroadenoma 2 | 559
gastric carcinoma 2 | 807
interstitial cystitis 2 | 2,312
nasopharyngeal carcinoma 2 | 1,058
primary Sjogren syndrome 2 | 735
Ameloblastoma 1 | 24
Amyloidosis 1 | 67
Bowen-Conradi syndrome 1 | 16
Chronic kidney disease stage 5 1 | 31
Congenital arteriovenous malformation 1 | 8
Diabetic retinopathy 1 | 56
Dubowitz syndrome 1 | 13
Hemangioma, Cavernous, Central Nervous System 1 | 2
Hemangiosarcoma 1 | 18
Mucopolysaccharidosis VI 1 | 6
NEPHRONOPHTHISIS 18 1 | 1
NEPHRONOPHTHISIS 2 1 | 5
Nephritis, Tubulointerstitial 1 | 8
Oculodentodigital dysplasia 1 | 14
Orofaciodigital syndrome 1 | 21
Platyspondyly 1 | 56
Retinopathy of prematurity 1 | 22
Shallow orbits 1 | 13
Skin Neoplasms 1 | 69
Thickening of glomerular basement membrane 1 | 7
Tubular atrophy 1 | 10
Ullrich congenital muscular dystrophy 1 | 5

Tissue

Blood and immune system 26 | 16,909
Cardiovascular System 26 | 15,192
Digestive Tract 26 | 17,369
Endocrine System 26 | 18,159
Female tissues 26 | 17,400
Liver and Pancreas 26 | 16,750
Male tissues 26 | 17,142
Nervous System 26 | 16,725
Respiratory system 26 | 16,393
Skin and soft tissues 26 | 17,230
Urinary Tract 26 | 16,678

Target Family

Non-IDG 18 | 12,091
Enzyme 5 | 4,145
GPCR 1 | 408
Kinase 1 | 634
Nuclear Receptor 1 | 48

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Folate receptor alpha FOLR1 Tchem Non-IDG -2.33242 206.1 303
Smoothened homolog SMO Tclin GPCR -1.17466 14.5 415
Transmembrane protein 100 TMEM100 Tbio Non-IDG -0.92226 8.79 100
Biogenesis of lysosome-related organelles complex 1 subunit 2 BLOC1S2 Tbio Non-IDG -2.89123 759.6 79
Nuclear receptor subfamily 6 group A member 1 NR6A1 Tbio Nuclear Receptor -2.36193 227.5 236
Set1/Ash2 histone methyltransferase complex subunit ASH2 ASH2L Tbio Enzyme -1.56543 33.7 261
Myosin-10 MYH10 Tbio Non-IDG -1.77478 55.4 94
COP9 signalosome complex subunit 1 GPS1 Tbio Non-IDG -1.62973 42.8 246
Protein diaphanous homolog 3 DIAPH3 Tbio Non-IDG -1.73720 59.7 189
Fat storage-inducing transmembrane protein 2 FITM2 Tdark Non-IDG -1.27967 17.3 2