Development Level

Tbio 7 | 11,445
Tchem 2 | 1,598
Tdark 2 | 6,588
Tclin 1 | 613

Collection

Ion Channel: IDG Consortium (T... 1 | 99
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

abnormal pelvic girdle bone mo... 12 | 12
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

Carcinoma 10 | 11,493
osteosarcoma 9 | 7,950
atypical teratoid / rhabdoid tumor 7 | 5,112
medulloblastoma, large-cell 6 | 6,241
glioblastoma 5 | 5,792
Breast cancer 4 | 3,578
Pick disease 4 | 1,894
cystic fibrosis 4 | 1,696
ependymoma 4 | 4,679
group 4 medulloblastoma 4 | 1,855
invasive ductal carcinoma 4 | 2,951
non-small cell lung cancer 4 | 2,890
oligodendroglioma 4 | 2,850
ovarian cancer 4 | 8,520
psoriasis 4 | 6,694
Astrocytoma, Pilocytic 3 | 3,081
Autosomal recessive predisposition 3 | 1,442
adult high grade glioma 3 | 3,801
ductal carcinoma in situ 3 | 1,745
esophageal adenocarcinoma 3 | 737
group 3 medulloblastoma 3 | 4,104
interstitial cystitis 3 | 2,312
lung cancer 3 | 4,740
lung carcinoma 3 | 2,843
malignant mesothelioma 3 | 3,232
primitive neuroectodermal tumor 3 | 3,035
Failure to gain weight 2 | 365
Genu varum 2 | 29
Kidney cancer 2 | 2,613
Kidney disease 2 | 430
Pediatric failure to thrive 2 | 365
astrocytic glioma 2 | 2,597
breast carcinoma 2 | 1,638
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
lung adenocarcinoma 2 | 2,716
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
progressive supranuclear palsy 2 | 676
subependymal giant cell astrocytoma 2 | 2,287
tuberculosis and treatment for 6 months 2 | 409
ulcerative colitis 2 | 1,819
Achondrogenesis 1 | 6
Acrofacial dysostosis 1 | 8
Addison's disease 1 | 31
Aicardi-Goutieres syndrome 1 | 19
Asphyxiating thoracic dystrophy 2 1 | 2
Aspiration pneumonitis 1 | 6
Blastic phase chronic myeloid leukemia 1 | 58
Bone Diseases, Developmental 1 | 27
Bronchiectasis 1 | 64
Cerebral Ischemia 1 | 37
Chronic Myelocytic Leukemia Accelerated Phase 1 | 59
Cleft Soft Palate 1 | 7
Decreased plasma renin activity 1 | 9
Degenerative disc disease 1 | 35
Delayed epiphyseal ossification 1 | 10
Delayed maturation of end part of long bone 1 | 10
Edema 1 | 81
Enlargement of the costochondral junction 1 | 4
Femoral bowing 1 | 20
Fibular bowing 1 | 5
Gastrointestinal stromal tumor 1 | 62
Generalized aminoaciduria 1 | 9
Hyperactive renin-angiotensin system 1 | 8
Hyperkalemia 1 | 17
Hypokalemia Prevention 1 | 6
Hyponatremia 1 | 25
Hypotension 1 | 82
Idiopathic bronchiectasis 1 | 4
Increased plasma renin activity 1 | 8
Increased serum parathyroid hormone 1 | 14
Irregular epiphyses 1 | 10
Irregular vertebral endplates 1 | 16
Irritation - emotion 1 | 68
Jeune thoracic dystrophy 1 | 10
Liddle syndrome 1 | 14
MENTAL RETARDATION, AUTOSOMAL RECESSIVE 54 1 | 1
Metaphyseal dysplasia 1 | 11
Metaphyseal irregularity 1 | 23
Multiple epiphyseal dysplasia 1 | 18
Osteochondritis dissecans 1 | 17
Pancreatic Neuroendocrine Tumor 1 | 45
Peripheral Edema due to Chronic Heart Failure 1 | 10
Platyspondyly 1 | 56
Pseudoachondroplasia 1 | 14
Pseudohypoaldosteronism, Type I, Autosomal Recessive 1 | 3
Pulmonary Edema due to Chronic Heart Failure 1 | 6
Relative short stature 1 | 13
Renal salt wasting 1 | 18
Sensenbrenner syndrome 1 | 17
Severe myopia 1 | 22
Short hands 1 | 50
Short rib-polydactyly syndrome, Verma-Naumoff type 1 | 5
Short stature, mild 1 | 13
Short-rib thoracic dysplasia 3 with or without polydactyly 1 | 9
Spinal stenosis 1 | 19
Stickler syndrome 1 | 13
Thoracic Diseases 1 | 3
Tibial bowing 1 | 19
Widely patent fontanels and sutures 1 | 12
autosomal recessive pseudohypoaldosteronism type 1 1 | 3

Tissue

Blood and immune system 12 | 16,909
Digestive Tract 12 | 17,369
Endocrine System 12 | 18,159
Female tissues 12 | 17,400
Liver and Pancreas 12 | 16,750
Male tissues 12 | 17,142
Nervous System 12 | 16,725
Respiratory system 12 | 16,393
Skin and soft tissues 12 | 17,230
Urinary Tract 12 | 16,678
Cardiovascular System 10 | 15,192

Target Family

Non-IDG 6 | 12,091
Enzyme 2 | 4,145
Kinase 2 | 634
Ion Channel 1 | 344
Transcription Factor 1 | 1,400

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
TRAF2 and NCK-interacting protein kinase TNIK Tchem Kinase -1.33394 28.5 441
Ubiquitin-conjugating enzyme E2 G1 UBE2G1 Tbio Non-IDG -0.84360 6.17 155
Leucine-rich repeat serine/threonine-protein kinase 1 LRRK1 Tbio Kinase -1.33128 18.1 134
Tetratricopeptide repeat protein 28 TTC28 Tdark Non-IDG -0.50526 3.76 3
Intraflagellar transport protein 80 homolog IFT80 Tbio Non-IDG -0.92606 9.26 52
Amiloride-sensitive sodium channel subunit beta SCNN1B Tclin Ion Channel -1.75374 52.6 316
25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial CYP27B1 Tchem Enzyme -2.70628 492.9 68
SPARC-related modular calcium-binding protein 1 SMOC1 Tbio Non-IDG -1.14486 16.3 97
CMRF35-like molecule 9 CD300LG Tdark Non-IDG -0.92828 10.3 49
Histone H2A deubiquitinase MYSM1 MYSM1 Tbio Transcription Factor -1.76987 62.1 184