Development Level

Tbio 2 | 11,445
Tdark 1 | 6,588

IMPC Phenotype

abnormal outer ear morphology 3 | 3
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

Carcinoma 3 | 11,493
glioblastoma 3 | 5,792
medulloblastoma, large-cell 3 | 6,241
ovarian cancer 3 | 8,520
Kidney cancer 2 | 2,613
Rheumatoid arthritis 2 | 1,191
adult high grade glioma 2 | 3,801
lung cancer 2 | 4,740
osteosarcoma 2 | 7,950
Absent reflex 1 | 92
Absent tendon reflex 1 | 92
Amyotrophic lateral sclerosis 1 | 451
Amyotrophic neuralgia 1 | 13
Astrocytoma, Pilocytic 1 | 3,081
Axonal degeneration/regeneration 1 | 7
Barrett's esophagus 1 | 182
Birthmark 1 | 35
Brain hemorrhage 1 | 14
Cafe-au-Lait Spots 1 | 37
Cerebral Hemorrhage 1 | 42
Charcot-Marie-Tooth disease 1 | 62
Chronic Lymphocytic Leukemia 1 | 262
Congenital Bilateral Cataracts 1 | 50
Congenital cataract 1 | 50
Congenital pes cavus 1 | 88
Congestive heart failure 1 | 113
Coronary artery disease 1 | 268
Cowden disease 1 | 18
Decreased motor NCV 1 | 22
Decreased number of large and small myelinated fibers 1 | 20
Decreased tendon reflex 1 | 122
Distal amyotrophy 1 | 51
Distal limb muscle weakness due to peripheral neuropathy 1 | 62
Distal muscle weakness 1 | 62
Distal sensory impairment 1 | 52
Elevated heart rate 1 | 25
Elevated urinary norepinephrine 1 | 5
Fatty liver disease 1 | 103
Foot dorsiflexor weakness 1 | 27
Foot-drop 1 | 27
Gait, Drop Foot 1 | 24
Hammer Toe 1 | 23
Heart failure 1 | 162
Hemangioma 1 | 69
Hypercalcemia 1 | 59
Hyperhidrosis disorder 1 | 81
Hypertension, episodic 1 | 5
Hypertensive Retinopathy 1 | 14
Increased sweating 1 | 81
Large intestine cancer 1 | 126
Liver cancer 1 | 604
Multiple Sclerosis 1 | 540
Neuroblastoma 1 | 80
Neuroblastoma, Susceptibility to 1 | 2
Neurodegenerative disease 1 | 414
Neuropathy 1 | 261
Onion bulb formation 1 | 19
Osteoporosis 1 | 363
Paraganglioma 1 | 15
Peripheral axonal atrophy 1 | 4
Pheochromocytoma 1 | 24
Polyneuropathy 1 | 64
Positive regitine blocking test 1 | 5
Progressive muscular atrophy 1 | 7
Proteinuria 1 | 144
Reflex, Deep Tendon, Absent 1 | 92
Renal Artery Stenosis 1 | 9
Sezary's disease 1 | 15
Slow progression 1 | 89
Sweating 1 | 81
Tachycardia 1 | 43
Waldenstrons macroglobulinemia 1 | 765
acute myeloid leukemia 1 | 783
adrenocortical adenoma 1 | 131
adrenocortical carcinoma 1 | 1,428
aldosterone-producing adenoma 1 | 665
astrocytic glioma 1 | 2,597
astrocytoma 1 | 1,146
atypical teratoid / rhabdoid tumor 1 | 5,112
chronic rhinosinusitis 1 | 512
dermatomyositis 1 | 966
esophageal adenocarcinoma 1 | 737
gastric carcinoma 1 | 807
group 3 medulloblastoma 1 | 4,104
inflammatory breast cancer 1 | 286
interstitial cystitis 1 | 2,312
interstitial lung disease 1 | 298
intraductal papillary-mucinous adenoma (IPMA) 1 | 2,955
mucosa-associated lymphoid tissue lymphoma 1 | 484
nephrosclerosis 1 | 333
non diabetic and post-ischemic heart failure 1 | 200
non primary Sjogren syndrome sicca 1 | 891
non-small cell lung cancer 1 | 2,890
oligodendroglioma 1 | 2,850
pituitary cancer 1 | 1,972
posterior fossa group A ependymoma 1 | 468
primary pancreatic ductal adenocarcinoma 1 | 1,109
subependymal giant cell astrocytoma 1 | 2,287
type 2 diabetes 1 | 9
ulcerative colitis 1 | 1,819

Tissue

Blood and immune system 3 | 16,909
Cardiovascular System 3 | 15,192
Digestive Tract 3 | 17,369
Endocrine System 3 | 18,159
Female tissues 3 | 17,400
Liver and Pancreas 3 | 16,750
Male tissues 3 | 17,142
Nervous System 3 | 16,725
Respiratory system 3 | 16,393
Skin and soft tissues 3 | 17,230
Urinary Tract 3 | 16,678

Target Family

Kinase 1 | 634
Non-IDG 1 | 12,091
Transcription Factor 1 | 1,400

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Basic helix-loop-helix domain-containing protein USF3 USF3 Tdark Transcription Factor -0.08389 1.16 14
Tribbles homolog 1 TRIB1 Tbio Kinase -1.74370 59.4 250
Kinesin-like protein KIF1B KIF1B Tbio Non-IDG -2.08306 118.0 60