Development Level

Tbio 5 | 10,625
Tchem 2 | 1,890
Tdark 1 | 7,003

IMPC Term

abnormal neural tube morpholog... 8 | 8
preweaning lethality, complete... 633 | 633
preweaning lethality, incomple... 260 | 260
abnormal behavior 226 | 226
decreased lean body mass 195 | 195
embryonic lethality prior to t... 187 | 187
decreased total body fat amoun... 186 | 186
decreased body weight 174 | 174
decreased bone mineral content 157 | 157
embryonic lethality prior to o... 148 | 148
abnormal bone structure 131 | 131
increased or absent threshold ... 128 | 128
decreased bone mineral density 126 | 126
decreased grip strength 123 | 123
decreased circulating glucose ... 121 | 121
increased circulating alkaline... 119 | 119
abnormal embryo size 112 | 112
enlarged heart 111 | 111
decreased body length 108 | 108
hyperactivity 108 | 108
increased lean body mass 107 | 107
abnormal retina morphology 100 | 100
increased mean corpuscular hem... 93 | 93
increased bone mineral content 92 | 92
increased mean corpuscular vol... 91 | 91
hypoactivity 89 | 89
decreased circulating choleste... 85 | 85
decreased circulating triglyce... 83 | 83
increased grip strength 83 | 83
short tibia 82 | 82
decreased circulating serum al... 79 | 79
decreased circulating HDL chol... 77 | 77
decreased circulating insulin ... 75 | 75
abnormal lens morphology 73 | 73
increased circulating sodium l... 71 | 71
increased fasted circulating g... 68 | 68
prenatal lethality prior to he... 64 | 64
abnormal sleep behavior 63 | 63
increased circulating HDL chol... 63 | 63
decreased lumbar vertebrae num... 62 | 62
increased sacral vertebrae num... 62 | 62
male infertility 62 | 62
abnormal retinal pigmentation 61 | 61
decreased rib number 59 | 59
increased total body fat amoun... 57 | 57
improved glucose tolerance 56 | 56
increased exploration in new e... 56 | 56
abnormal bone mineralization 55 | 55
abnormal coat/hair pigmentatio... 54 | 54
decreased leukocyte cell numbe... 54 | 54
decreased circulating alanine ... 53 | 53
decreased hemoglobin content 53 | 53
increased circulating choleste... 53 | 53
abnormal behavioral response t... 52 | 52
decreased prepulse inhibition 52 | 52
impaired glucose tolerance 52 | 52
increased bone mineral density 52 | 52
abnormal gait 51 | 51
abnormal heart morphology 51 | 51
decreased mean corpuscular vol... 50 | 50
decreased caudal vertebrae num... 49 | 49
decreased fasted circulating g... 49 | 49
decreased startle reflex 48 | 48
abnormal seminal vesicle morph... 47 | 47
thrombocytopenia 46 | 46
increased hemoglobin content 45 | 45
decreased heart weight 44 | 44
increased blood urea nitrogen ... 44 | 44
decreased erythrocyte cell num... 43 | 43
increased circulating chloride... 43 | 43
increased body weight 42 | 42
decreased circulating alkaline... 41 | 41
decreased circulating total pr... 41 | 41
decreased eosinophil cell numb... 41 | 41
increased rib number 41 | 41
decreased circulating free fat... 39 | 39
abnormal eye morphology 38 | 38
increased startle reflex 38 | 38
abnormal neural tube closure 37 | 37
decreased circulating LDL chol... 37 | 37
decreased neutrophil cell numb... 37 | 37
increased heart weight 37 | 37
increased leukocyte cell numbe... 37 | 37
small testis 37 | 37
abnormal spleen morphology 36 | 36
increased hematocrit 36 | 36
cardiovascular system phenotyp... 35 | 35
limb grasping 35 | 35
decreased mean corpuscular hem... 34 | 34
female infertility 34 | 34
tremors 34 | 34
decreased circulating calcium ... 33 | 33
abnormal cranium morphology 32 | 32
decreased circulating chloride... 32 | 32
decreased threshold for audito... 32 | 32
increased circulating calcium ... 32 | 32
abnormal epididymis morphology 31 | 31
decreased T cell number 31 | 31
decreased blood urea nitrogen ... 31 | 31
decreased circulating fructosa... 31 | 31
increased circulating potassiu... 31 | 31

Disease

ovarian cancer 5 | 8,484
lung cancer 3 | 4,466
Cavernous hemangioma 2 | 12
IGA Glomerulonephritis 2 | 454
acute myeloid leukemia 2 | 780
adult high grade glioma 2 | 2,148
chronic lymphosyte leukemia 2 | 232
diabetes mellitus 2 | 1,663
ependymoma 2 | 2,514
glioblastoma 2 | 5,572
hepatocellular carcinoma 2 | 532
malignant mesothelioma 2 | 3,162
medulloblastoma, large-cell 2 | 6,234
osteosarcoma 2 | 7,933
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,795
primary Sjogren syndrome 2 | 789
psoriasis 2 | 6,685
tuberculosis 2 | 1,557
Arteriovenous malformation 1 | 8
Arthritis 1 | 248
Atherosclerosis 1 | 275
Breast cancer 1 | 3,094
Cancer 1 | 2,346
Cavernous Hemangioma of Brain 1 | 1
Cavernous Malformations of CNS and Retina 1 | 1
Cerebral angioma 1 | 1
Cerebrovascular disease 1 | 231
Colitis 1 | 46
Colorectal Neoplasms 1 | 217
Dermatitis, Allergic Contact 1 | 66
Diphtheria 1 | 23
Epidermodysplasia verruciformis 1 | 21
Fatty liver disease 1 | 84
Hemangioma, Cavernous, Central Nervous System 1 | 2
Hyperandrogenism 1 | 32
Hyperkeratotic Cutaneous Capillary-Venous Malformations Associated With Cerebral Capillary Malformations 1 | 1
Hypertension 1 | 287
Klippel-Trenaunay syndrome 1 | 15
Melanoma 1 | 261
Metabolic syndrome X 1 | 155
Mitochondrial Phosphate Carrier Deficiency 1 | 1
Mucoepidermoid carcinoma 1 | 19
Multiple cutaneous and mucosal venous malformations 1 | 10
Mumps 1 | 10
Obesity 1 | 616
Palmoplantar keratosis 1 | 36
Pick disease 1 | 1,893
Pityriasis rubra pilaris 1 | 5
Polycystic Ovary Syndrome 1 | 332
Pontocerebellar hypoplasia 1 | 29
Rheumatoid Arthritis 1 | 1,160
Threatened abortion 1 | 1
acute quadriplegic myopathy 1 | 1,157
adrenocortical carcinoma 1 | 1,427
aldosterone-producing adenoma 1 | 664
astrocytic glioma 1 | 2,241
atypical teratoid / rhabdoid tumor 1 | 4,369
axial spondyloarthropathy 1 | 28
chronic kidney disease 1 | 90
gastric carcinoma 1 | 832
group 3 medulloblastoma 1 | 2,254
group 4 medulloblastoma 1 | 1,875
head and neck cancer 1 | 270
hereditary spastic paraplegia 1 | 313
interstitial cystitis 1 | 2,299
interstitial lung disease 1 | 291
intraductal papillary-mucinous adenoma (IPMA) 1 | 2,956
mucosa-associated lymphoid tissue lymphoma 1 | 480
non primary Sjogren syndrome sicca 1 | 840
non-small cell lung cancer 1 | 2,798
pancreatic cancer 1 | 2,300
permanent atrial fibrillation 1 | 44
pilocytic astrocytoma 1 | 3,086
pituitary cancer 1 | 1,972
posterior fossa group B ependymoma 1 | 1,530
progressive supranuclear palsy 1 | 674
sonic hedgehog group medulloblastoma 1 | 1,482
ulcerative colitis 1 | 2,087
urothelial carcinoma 1 | 318

Tissue

Blood and immune system 8 | 17,995
Cardiovascular System 8 | 17,958
Digestive Tract 8 | 18,473
Endocrine System 8 | 18,512
Female tissues 8 | 18,647
Liver and Pancreas 8 | 18,136
Male tissues 8 | 17,969
Nervous System 8 | 18,561
Respiratory system 8 | 17,484
Skin and soft tissues 8 | 18,115
Urinary Tract 8 | 18,444

Target Family

Non-IDG 5 | 11,971
Enzyme 1 | 4,146
Nuclear Receptor 1 | 48
Transporter 1 | 473

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Progesterone-induced-blocking factor 1 PIBF1 Tbio Non-IDG -1.20835 19.9 201
Phosphate carrier protein, mitochondrial SLC25A3 Tbio Transporter -2.78608 635.1 25
Pre-mRNA-splicing factor 18 PRPF18 Tbio Non-IDG -1.30287 19.2 78
Complement component receptor 1-like protein CR1L Tdark Non-IDG 0.06 1.58 26
Krev interaction trapped protein 1 KRIT1 Tbio Non-IDG -2.11495 152.1 145
Nuclear receptor subfamily 6 group A member 1 NR6A1 Tbio Nuclear Receptor -2.29502 209.4 202
Histone chaperone ASF1A ASF1A Tchem Non-IDG -1.45315 30.5 251
Nicotinamide phosphoribosyltransferase NAMPT Tchem Enzyme -2.87146 962.2 580