Development Level

Tbio 7 | 11,651
Tchem 3 | 1,388
Tclin 1 | 612
Tdark 1 | 6,593

IMPC Phenotype

abnormal neural tube morpholog... 12 | 12
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

Carcinoma 9 | 11,493
ovarian cancer 8 | 8,520
lung cancer 6 | 4,740
diabetes mellitus 4 | 1,728
ependymoma 4 | 4,679
glioblastoma 4 | 5,792
medulloblastoma, large-cell 4 | 6,241
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
Cancer 3 | 2,499
adult high grade glioma 3 | 3,801
atypical teratoid / rhabdoid tumor 3 | 5,112
group 3 medulloblastoma 3 | 4,104
malignant mesothelioma 3 | 3,232
osteosarcoma 3 | 7,950
psoriasis 3 | 6,694
tuberculosis 3 | 2,010
Autosomal recessive predisposition 2 | 1,442
Breast cancer 2 | 3,578
Cavernous hemangioma 2 | 11
Cerebrovascular disease 2 | 238
Epilepsy 2 | 792
Neural Tube Defects 2 | 31
Rheumatoid arthritis 2 | 1,191
Schizophrenia 2 | 1,160
Seizures 2 | 596
acute myeloid leukemia 2 | 783
hepatocellular carcinoma 2 | 547
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
non primary Sjogren syndrome sicca 2 | 891
non-small cell lung cancer 2 | 2,890
pituitary cancer 2 | 1,972
primary Sjogren syndrome 2 | 735
spina bifida 2 | 1,074
3-M syndrome 1 | 15
Abortion, Threatened 1 | 1
Acidosis, Lactic 1 | 97
Acute lymphoid leukemia 1 | 25
Alcoholic Intoxication, Chronic 1 | 289
Burkitt's lymphoma 1 | 15
Carcinoma of female breast 1 | 20
Cavernous Hemangioma of Brain 1 | 3
Cerebral calcification 1 | 43
Cerebral cavernous malformation 1 | 3
Colitis 1 | 54
Colorectal Neoplasms 1 | 243
Congenital Heart Defects 1 | 58
Congenital heart disease 1 | 93
Craniofacial Abnormalities 1 | 151
Cyanosis 1 | 17
Dermatologic disorders 1 | 93
Diabetes mellitus type 2 1 | 69
Epidermodysplasia verruciformis 1 | 21
Familial cerebral cavernous malformation 1 | 3
Fatty liver disease 1 | 103
Gestational trophoblastic neoplasia 1 | 14
Headache 1 | 37
Heart Defects, Congenital 1 | 37
Hemangioma 1 | 69
Homocystinuria 1 | 21
Hyperhomocysteinemia 1 | 37
Hypertrophic Cardiomyopathy 1 | 117
Increased serum lactate 1 | 60
Intracranial Hemorrhages 1 | 16
Juvenile rheumatoid arthritis 1 | 111
Klippel-Trenaunay syndrome 1 | 13
Lactic acidemia 1 | 95
Leigh disease 1 | 100
Long QT syndrome 1 | 39
Malignant tumor of head and/or neck 1 | 15
Mental deterioration in childhood 1 | 95
Metabolic acidosis 1 | 90
Mitochondrial Complex 1 Deficiency 1 | 28
Mitochondrial complex I deficiency 1 | 46
Mucoepidermoid carcinoma 1 | 26
Multiple cutaneous and mucosal venous malformations 1 | 10
Mycosis fungoides 1 | 29
NADH:Q(1) Oxidoreductase deficiency 1 | 24
Nerve Degeneration 1 | 121
Neural tube defect, folate-sensitive 1 | 4
Neuro-degenerative disease 1 | 43
Neurodegenerative Disorders 1 | 79
Neurodevelopmental regression 1 | 95
Non-Hodgkin's lymphoma 1 | 22
Ovarian Neoplasms 1 | 102
Palmoplantar keratosis 1 | 74
Pilocytic astrocytoma 1 | 56
Pontocerebellar hypoplasia 1 | 36
Psychomotor regression beginning in infancy 1 | 95
Respiratory Insufficiency 1 | 132
Respiratory function loss 1 | 121
Threatened abortion 1 | 1
Treatment Refractory Type 2 Diabetes Mellitus 1 | 53
axial spondyloarthropathy 1 | 28
chronic kidney disease 1 | 90
hereditary spastic paraplegia 1 | 318
interstitial lung disease 1 | 298
neural tube defect 1 | 9
ovarian neoplasm 1 | 99
permanent atrial fibrillation 1 | 45
posterior fossa group A ependymoma 1 | 468

Tissue

Blood and immune system 12 | 16,909
Digestive Tract 12 | 17,369
Female tissues 12 | 17,400
Nervous System 12 | 16,725
Skin and soft tissues 12 | 17,230
Cardiovascular System 11 | 15,192
Endocrine System 11 | 18,159
Liver and Pancreas 11 | 16,750
Male tissues 11 | 17,142
Respiratory system 11 | 16,393
Urinary Tract 11 | 16,678

Target Family

Non-IDG 6 | 12,091
Enzyme 4 | 4,145
Nuclear Receptor 1 | 48
Transporter 1 | 473

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Nicotinamide phosphoribosyltransferase NAMPT Tchem Enzyme -2.94790 1054.3 667
NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial NDUFS7 Tclin Enzyme -2.93249 793.4 94
Putative Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase ALG10B Tbio Enzyme -1.32430 19.1 69
C-1-tetrahydrofolate synthase, cytoplasmic MTHFD1 Tbio Enzyme -1.97029 90.6 101
Progesterone-induced-blocking factor 1 PIBF1 Tbio Non-IDG -1.30666 21.1 209
Pre-mRNA-splicing factor 18 PRPF18 Tbio Non-IDG -1.36183 19.8 84
Folate receptor alpha FOLR1 Tchem Non-IDG -2.33242 206.1 303
Phosphate carrier protein, mitochondrial SLC25A3 Tbio Transporter -2.85426 703.4 33
Complement component receptor 1-like protein CR1L Tdark Non-IDG -0.13712 1.58 29
Nuclear receptor subfamily 6 group A member 1 NR6A1 Tbio Nuclear Receptor -2.36193 227.5 236