Development Level

Tbio 24 | 10,625
Tchem 9 | 1,890
Tdark 3 | 7,003
Tclin 1 | 602

IMPC Term

abnormal neural tube closure 37 | 37
preweaning lethality, complete... 633 | 633
preweaning lethality, incomple... 260 | 260
abnormal behavior 226 | 226
decreased lean body mass 195 | 195
embryonic lethality prior to t... 187 | 187
decreased total body fat amoun... 186 | 186
decreased body weight 174 | 174
decreased bone mineral content 157 | 157
embryonic lethality prior to o... 148 | 148
abnormal bone structure 131 | 131
increased or absent threshold ... 128 | 128
decreased bone mineral density 126 | 126
decreased grip strength 123 | 123
decreased circulating glucose ... 121 | 121
increased circulating alkaline... 119 | 119
abnormal embryo size 112 | 112
enlarged heart 111 | 111
decreased body length 108 | 108
hyperactivity 108 | 108
increased lean body mass 107 | 107
abnormal retina morphology 100 | 100
increased mean corpuscular hem... 93 | 93
increased bone mineral content 92 | 92
increased mean corpuscular vol... 91 | 91
hypoactivity 89 | 89
decreased circulating choleste... 85 | 85
decreased circulating triglyce... 83 | 83
increased grip strength 83 | 83
short tibia 82 | 82
decreased circulating serum al... 79 | 79
decreased circulating HDL chol... 77 | 77
decreased circulating insulin ... 75 | 75
abnormal lens morphology 73 | 73
increased circulating sodium l... 71 | 71
increased fasted circulating g... 68 | 68
prenatal lethality prior to he... 64 | 64
abnormal sleep behavior 63 | 63
increased circulating HDL chol... 63 | 63
decreased lumbar vertebrae num... 62 | 62
increased sacral vertebrae num... 62 | 62
male infertility 62 | 62
abnormal retinal pigmentation 61 | 61
decreased rib number 59 | 59
increased total body fat amoun... 57 | 57
improved glucose tolerance 56 | 56
increased exploration in new e... 56 | 56
abnormal bone mineralization 55 | 55
abnormal coat/hair pigmentatio... 54 | 54
decreased leukocyte cell numbe... 54 | 54
decreased circulating alanine ... 53 | 53
decreased hemoglobin content 53 | 53
increased circulating choleste... 53 | 53
abnormal behavioral response t... 52 | 52
decreased prepulse inhibition 52 | 52
impaired glucose tolerance 52 | 52
increased bone mineral density 52 | 52
abnormal gait 51 | 51
abnormal heart morphology 51 | 51
decreased mean corpuscular vol... 50 | 50
decreased caudal vertebrae num... 49 | 49
decreased fasted circulating g... 49 | 49
decreased startle reflex 48 | 48
abnormal seminal vesicle morph... 47 | 47
thrombocytopenia 46 | 46
increased hemoglobin content 45 | 45
decreased heart weight 44 | 44
increased blood urea nitrogen ... 44 | 44
decreased erythrocyte cell num... 43 | 43
increased circulating chloride... 43 | 43
increased body weight 42 | 42
decreased circulating alkaline... 41 | 41
decreased circulating total pr... 41 | 41
decreased eosinophil cell numb... 41 | 41
increased rib number 41 | 41
decreased circulating free fat... 39 | 39
abnormal eye morphology 38 | 38
increased startle reflex 38 | 38
decreased circulating LDL chol... 37 | 37
decreased neutrophil cell numb... 37 | 37
increased heart weight 37 | 37
increased leukocyte cell numbe... 37 | 37
small testis 37 | 37
abnormal spleen morphology 36 | 36
increased hematocrit 36 | 36
cardiovascular system phenotyp... 35 | 35
limb grasping 35 | 35
decreased mean corpuscular hem... 34 | 34
female infertility 34 | 34
tremors 34 | 34
decreased circulating calcium ... 33 | 33
abnormal cranium morphology 32 | 32
decreased circulating chloride... 32 | 32
decreased threshold for audito... 32 | 32
increased circulating calcium ... 32 | 32
abnormal epididymis morphology 31 | 31
decreased T cell number 31 | 31
decreased blood urea nitrogen ... 31 | 31
decreased circulating fructosa... 31 | 31
increased circulating potassiu... 31 | 31

Disease

ovarian cancer 25 | 8,484
glioblastoma 16 | 5,572
lung cancer 16 | 4,466
medulloblastoma, large-cell 16 | 6,234
osteosarcoma 16 | 7,933
intraductal papillary-mucinous neoplasm (IPMN) 14 | 3,289
psoriasis 14 | 6,685
Carcinoma 13 | 2,147
Breast cancer 11 | 3,094
atypical teratoid / rhabdoid tumor 11 | 4,369
breast carcinoma 10 | 1,614
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,988
lung adenocarcinoma 10 | 2,713
Cancer 9 | 2,346
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,956
invasive ductal carcinoma 9 | 2,950
malignant mesothelioma 9 | 3,162
oligodendroglioma 9 | 2,849
pancreatic cancer 9 | 2,300
astrocytoma 8 | 1,493
non-small cell lung cancer 8 | 2,798
pediatric high grade glioma 8 | 2,712
primitive neuroectodermal tumor 8 | 3,031
ependymoma 7 | 2,514
pilocytic astrocytoma 7 | 3,086
pituitary cancer 7 | 1,972
adrenocortical carcinoma 6 | 1,427
ductal carcinoma in situ 6 | 1,745
lung carcinoma 6 | 2,844
medulloblastoma 6 | 1,524
spina bifida 6 | 1,064
Pick disease 5 | 1,893
astrocytic glioma 5 | 2,241
group 4 medulloblastoma 5 | 1,875
juvenile dermatomyositis 5 | 1,189
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,795
posterior fossa group B ependymoma 5 | 1,530
tuberculosis 5 | 1,557
ulcerative colitis 5 | 2,087
Cerebrovascular disease 4 | 231
acute myeloid leukemia 4 | 780
colon cancer 4 | 1,475
dermatomyositis 4 | 933
group 3 medulloblastoma 4 | 2,254
interstitial cystitis 4 | 2,299
primary pancreatic ductal adenocarcinoma 4 | 1,271
Intellectual disability 3 | 573
Obesity 3 | 616
Rheumatoid Arthritis 3 | 1,160
adult high grade glioma 3 | 2,148
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 499
cutaneous lupus erythematosus 3 | 1,056
gastric carcinoma 3 | 832
nasopharyngeal carcinoma 3 | 1,056
primary Sjogren syndrome 3 | 789
sonic hedgehog group medulloblastoma 3 | 1,482
Anoxia 2 | 33
Atopic dermatitis 2 | 944
Cataract 2 | 104
Cerebellar Ataxia 2 | 72
Coloboma 2 | 51
Craniofacial Abnormalities 2 | 147
Down syndrome 2 | 548
Duchenne muscular dystrophy 2 | 602
Familial Mediterranean fever 2 | 12
Gaucher disease type 1 2 | 171
IGA Glomerulonephritis 2 | 454
Microcephaly 2 | 149
Multiple myeloma 2 | 1,327
Polycystic kidney disease 2 | 54
Prostatic Neoplasms 2 | 471
Pyoderma gangrenosum 2 | 9
Schizophrenia 2 | 501
Vascular disease 2 | 281
Waldenstrons macroglobulinemia 2 | 765
acute quadriplegic myopathy 2 | 1,157
atypical teratoid/rhabdoid tumor 2 | 1,095
chronic rhinosinusitis 2 | 512
cystic fibrosis 2 | 1,665
diabetes mellitus 2 | 1,663
esophageal adenocarcinoma 2 | 737
fibroadenoma 2 | 557
glioblastoma multiforme 2 | 347
hepatocellular carcinoma 2 | 532
inflammatory breast cancer 2 | 404
nephrosclerosis 2 | 329
non primary Sjogren syndrome sicca 2 | 840
non-small cell lung carcinoma 2 | 413
pancreatic carcinoma 2 | 567
subependymal giant cell astrocytoma 2 | 2,287
tuberculosis and treatment for 6 months 2 | 686
AICARDI-GOUTIERES SYNDROME 1 1 | 5
Babesiosis 1 | 13
Baller-Gerold syndrome 1 | 14
Invasive Ductal Breast Carcinoma 1 | 9
Jaw Abnormalities 1 | 5
Lower Extremity Deformities, Congenital 1 | 2
Malignant hyperthermia 1 | 25
Nephrotic Syndrome 1 | 48
Pylorospasm 1 | 2

Tissue

Blood and immune system 37 | 17,995
Digestive Tract 37 | 18,473
Endocrine System 37 | 18,512
Female tissues 37 | 18,647
Liver and Pancreas 37 | 18,136
Nervous System 37 | 18,561
Urinary Tract 37 | 18,444
Cardiovascular System 36 | 17,958
Male tissues 36 | 17,969
Respiratory system 36 | 17,484
Skin and soft tissues 36 | 18,115

Target Family

Non-IDG 14 | 11,971
Enzyme 11 | 4,146
Transcription Factor 4 | 1,400
Kinase 3 | 634
Epigenetic 2 | 242
Ion Channel 1 | 341
Nuclear Receptor 1 | 48
Transporter 1 | 473

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Fibroblast growth factor receptor 1 FGFR1 Tclin Kinase -3.07424 1194.2 1600
Exocyst complex component 8 EXOC8 Tbio Non-IDG -1.17455 14.6 65
Anaphase-promoting complex subunit 15 ANAPC15 Tdark Enzyme -0.41378 2.22 21
Vacuolar protein sorting-associated protein 13D VPS13D Tdark Non-IDG -0.09691 1.08 6
Progesterone-induced-blocking factor 1 PIBF1 Tbio Non-IDG -1.20835 19.9 201
Cat eye syndrome critical region protein 2 CECR2 Tchem Epigenetic -2.15563 142.8 42
Absent in melanoma 1 protein AIM1 Tbio Non-IDG -1.08254 11.8 9
Transmembrane protein 100 TMEM100 Tbio Non-IDG -0.77167 7.27 72
Lysosomal-associated transmembrane protein 4B LAPTM4B Tbio Non-IDG -1.79912 76.3 80
Suppressor of fused homolog SUFU Tbio Non-IDG -2.26339 185.5 162