Development Level

Tbio 32 | 11,445
Tchem 9 | 1,598
Tdark 5 | 6,588

IMPC Phenotype

abnormal neural tube closure 46 | 46
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

ovarian cancer 29 | 8,520
Carcinoma 28 | 11,493
lung cancer 18 | 4,740
medulloblastoma, large-cell 18 | 6,241
osteosarcoma 18 | 7,950
glioblastoma 15 | 5,792
intraductal papillary-mucinous neoplasm (IPMN) 15 | 3,291
psoriasis 15 | 6,694
atypical teratoid / rhabdoid tumor 13 | 5,112
Breast cancer 12 | 3,578
Cancer 12 | 2,499
group 3 medulloblastoma 12 | 4,104
breast carcinoma 11 | 1,638
malignant mesothelioma 11 | 3,232
lung adenocarcinoma 10 | 2,716
pituitary cancer 10 | 1,972
invasive ductal carcinoma 9 | 2,951
Autosomal recessive predisposition 8 | 1,442
Kidney cancer 8 | 2,613
ependymoma 8 | 4,679
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
non-small cell lung cancer 8 | 2,890
adult high grade glioma 7 | 3,801
astrocytoma 7 | 1,146
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,962
spina bifida 7 | 1,074
Rheumatoid arthritis 6 | 1,191
acute myeloid leukemia 6 | 783
ductal carcinoma in situ 6 | 1,745
lung carcinoma 6 | 2,843
pancreatic cancer 6 | 2,398
primitive neuroectodermal tumor 6 | 3,035
tuberculosis 6 | 2,010
diabetes mellitus 5 | 1,728
interstitial cystitis 5 | 2,312
oligodendroglioma 5 | 2,850
Astrocytoma, Pilocytic 4 | 3,081
Epilepsy 4 | 792
Failure to gain weight 4 | 365
Infantile onset 4 | 238
Intellectual disability 4 | 1,016
Pediatric failure to thrive 4 | 365
Pick disease 4 | 1,894
Schizophrenia 4 | 1,160
Seizures 4 | 596
adrenocortical carcinoma 4 | 1,428
astrocytic glioma 4 | 2,597
colon cancer 4 | 1,478
cutaneous lupus erythematosus 4 | 1,057
dermatomyositis 4 | 966
group 4 medulloblastoma 4 | 1,855
pediatric high grade glioma 4 | 1,064
Cataract 3 | 297
Cerebellar Ataxia 3 | 304
Cerebral atrophy 3 | 178
Cleft Palate 3 | 271
Cognitive delay 3 | 608
Global developmental delay 3 | 608
Liver Dysfunction 3 | 99
Melanoma 3 | 711
Mental and motor retardation 3 | 608
Multiple myeloma 3 | 1,332
Muscle hypotonia 3 | 571
Neural Tube Defects 3 | 31
Obesity 3 | 678
Short stature 3 | 531
Waldenstrons macroglobulinemia 3 | 765
esophageal adenocarcinoma 3 | 737
juvenile dermatomyositis 3 | 1,187
medulloblastoma 3 | 720
nasopharyngeal carcinoma 3 | 1,058
nephrosclerosis 3 | 333
non primary Sjogren syndrome sicca 3 | 891
posterior fossa group A ependymoma 3 | 468
ulcerative colitis 3 | 1,819
Atopic dermatitis 2 | 952
Bipolar Disorder 2 | 666
Carcinoma, Hepatocellular 2 | 228
Cerebrovascular disease 2 | 238
Decreased liver function 2 | 24
Diarrhea 2 | 253
Endometriosis 2 | 540
Frontal bossing 2 | 157
Hepatomegaly 2 | 285
Hypoxia 2 | 33
Liver cancer 2 | 604
Liver carcinoma 2 | 240
Methylmalonic acidemia 2 | 37
Sensorineural Hearing Loss (disorder) 2 | 284
Strabismus 2 | 270
Vascular disease 2 | 319
Ventricular Septal Defects 2 | 119
fibroadenoma 2 | 559
gastric carcinoma 2 | 807
glioblastoma multiforme 2 | 142
hepatocellular carcinoma 2 | 547
primary Sjogren syndrome 2 | 735
primary pancreatic ductal adenocarcinoma 2 | 1,109
subependymal giant cell astrocytoma 2 | 2,287

Tissue

Blood and immune system 46 | 16,909
Digestive Tract 46 | 17,369
Endocrine System 46 | 18,159
Female tissues 46 | 17,400
Liver and Pancreas 46 | 16,750
Male tissues 46 | 17,142
Respiratory system 46 | 16,393
Skin and soft tissues 46 | 17,230
Urinary Tract 46 | 16,678
Nervous System 45 | 16,725
Cardiovascular System 43 | 15,192

Target Family

Non-IDG 18 | 12,091
Enzyme 16 | 4,145
Kinase 3 | 634
Transcription Factor 3 | 1,400
Transporter 3 | 473
Epigenetic 2 | 242
Nuclear Receptor 1 | 48

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cat eye syndrome critical region protein 2 CECR2 Tchem Epigenetic -2.17030 147.0 44
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit DDOST Tchem Enzyme -1.60313 44.1 140
Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial COQ6 Tbio Enzyme -1.26796 18.5 102
Lysosomal-associated transmembrane protein 4B LAPTM4B Tbio Non-IDG -1.90763 86.1 91
Polycomb group RING finger protein 1 PCGF1 Tbio Non-IDG -0.99091 11.4 101
Folate receptor alpha FOLR1 Tchem Non-IDG -2.33242 206.1 303
Beta/gamma crystallin domain-containing protein 1 CRYBG1 Tbio Non-IDG -1.13797 12.4 13
Phosphate carrier protein, mitochondrial SLC25A3 Tbio Transporter -2.85426 703.4 33
Transmembrane protein 100 TMEM100 Tbio Non-IDG -0.92226 8.79 100
Progesterone-induced-blocking factor 1 PIBF1 Tbio Non-IDG -1.30666 21.1 209