Development Level

Tbio 19 | 11,445
Tdark 4 | 6,588
Tchem 3 | 1,598

IMPC Phenotype

abnormal lung morphology 26 | 26
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

ovarian cancer 19 | 8,520
Carcinoma 17 | 11,493
medulloblastoma, large-cell 13 | 6,241
osteosarcoma 12 | 7,950
glioblastoma 11 | 5,792
lung cancer 10 | 4,740
psoriasis 10 | 6,694
atypical teratoid / rhabdoid tumor 9 | 5,112
Breast cancer 8 | 3,578
ependymoma 8 | 4,679
lung adenocarcinoma 8 | 2,716
malignant mesothelioma 8 | 3,232
oligodendroglioma 8 | 2,850
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
Rheumatoid arthritis 6 | 1,191
adult high grade glioma 6 | 3,801
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
lung carcinoma 6 | 2,843
pituitary cancer 6 | 1,972
tuberculosis 6 | 2,010
Cancer 5 | 2,499
astrocytic glioma 5 | 2,597
astrocytoma 5 | 1,146
cystic fibrosis 5 | 1,696
group 3 medulloblastoma 5 | 4,104
interstitial cystitis 5 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
pancreatic cancer 5 | 2,398
subependymal giant cell astrocytoma 5 | 2,287
Astrocytoma, Pilocytic 4 | 3,081
Kidney cancer 4 | 2,613
Pick disease 4 | 1,894
Schizophrenia 4 | 1,160
adrenocortical carcinoma 4 | 1,428
colon cancer 4 | 1,478
invasive ductal carcinoma 4 | 2,951
non-small cell lung cancer 4 | 2,890
pediatric high grade glioma 4 | 1,064
primary pancreatic ductal adenocarcinoma 4 | 1,109
primitive neuroectodermal tumor 4 | 3,035
spina bifida 4 | 1,074
ulcerative colitis 4 | 1,819
Autosomal recessive predisposition 3 | 1,442
Diarrhea 3 | 253
Infantile onset 3 | 238
Kidney disease 3 | 430
Liver Cirrhosis, Experimental 3 | 769
Liver disease 3 | 237
Multiple Sclerosis 3 | 540
Polycystic ovary syndrome 3 | 360
Prostatic Neoplasms 3 | 495
active ulcerative colitis 3 | 764
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
diabetes mellitus 3 | 1,728
group 4 medulloblastoma 3 | 1,855
hepatocellular carcinoma 3 | 547
medulloblastoma 3 | 720
nasopharyngeal carcinoma 3 | 1,058
Acromegaly 2 | 51
Amyotrophic lateral sclerosis 2 | 451
Arthritis, Rheumatoid 2 | 174
Asthma 2 | 385
Autistic Disorder 2 | 364
Bladder Neoplasm 2 | 112
Breast Neoplasms 2 | 445
Carcinoma, Transitional Cell 2 | 32
Colonic Neoplasms 2 | 142
Colorectal Neoplasms 2 | 243
Duchenne muscular dystrophy 2 | 601
Failure to gain weight 2 | 365
HIV Infections 2 | 102
Kidney Diseases 2 | 114
Liver Cirrhosis 2 | 181
Lung Neoplasms 2 | 232
Mammary Neoplasms 2 | 425
Mesothelioma, Malignant 2 | 105
Muscle hypotonia 2 | 571
Nerve Degeneration 2 | 121
Neuropathy 2 | 261
Pediatric failure to thrive 2 | 365
Proteinuria 2 | 144
Renal Insufficiency 2 | 90
Reperfusion Injury 2 | 86
Retinitis Pigmentosa 2 | 226
Stomach Neoplasms 2 | 300
Type 2 diabetes mellitus 2 | 272
Urinary Bladder Neoplasms 2 | 114
active Crohn's disease 2 | 922
acute quadriplegic myopathy 2 | 1,158
breast carcinoma 2 | 1,638
cutaneous lupus erythematosus 2 | 1,057
dermatomyositis 2 | 966
ductal carcinoma in situ 2 | 1,745
esophageal adenocarcinoma 2 | 737
juvenile dermatomyositis 2 | 1,187
non diabetic and post-ischemic heart failure 2 | 200
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
Cryptococcosis 1 | 18
Primary immunodeficiency disease 1 | 54
Tuberous sclerosis 1 | 19

Tissue

Blood and immune system 26 | 16,909
Digestive Tract 26 | 17,369
Endocrine System 26 | 18,159
Liver and Pancreas 26 | 16,750
Skin and soft tissues 26 | 17,230
Urinary Tract 26 | 16,678
Cardiovascular System 25 | 15,192
Female tissues 25 | 17,400
Male tissues 25 | 17,142
Nervous System 25 | 16,725
Respiratory system 25 | 16,393

Target Family

Non-IDG 18 | 12,091
Enzyme 6 | 4,145
Transporter 2 | 473

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
RNA-binding protein Raly RALY Tbio Non-IDG -1.12263 14.4 176
Transmembrane protein 100 TMEM100 Tbio Non-IDG -0.92226 8.79 100
Calsyntenin-3 CLSTN3 Tbio Non-IDG -0.81358 6.83 24
ProSAAS PCSK1N Tbio Non-IDG -2.28833 188.0 73
Volume-regulated anion channel subunit LRRC8A LRRC8A Tbio Non-IDG -1.55179 39.4 129
Myelin protein P0 MPZ Tbio Non-IDG -2.55919 360.1 301
Methylmalonic aciduria and homocystinuria type C protein MMACHC Tbio Non-IDG -1.83573 76.5 233
Activity-dependent neuroprotector homeobox protein 2 ADNP2 Tdark Non-IDG -0.53148 2.71 58
Breast carcinoma-amplified sequence 1 BCAS1 Tbio Non-IDG -1.10984 10.0 147
Bile salt export pump ABCB11 Tchem Transporter -2.84131 702.2 144