Development Level

Tbio 19 | 11,445
Tclin 3 | 613
Tchem 1 | 1,598
Tdark 1 | 6,588

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

abnormal locomotor behavior 24 | 24
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

Carcinoma 17 | 11,493
ovarian cancer 16 | 8,520
psoriasis 15 | 6,694
glioblastoma 14 | 5,792
ependymoma 13 | 4,679
atypical teratoid / rhabdoid tumor 12 | 5,112
medulloblastoma, large-cell 12 | 6,241
osteosarcoma 12 | 7,950
adult high grade glioma 11 | 3,801
Breast cancer 10 | 3,578
primitive neuroectodermal tumor 10 | 3,035
Astrocytoma, Pilocytic 9 | 3,081
lung cancer 9 | 4,740
Kidney cancer 8 | 2,613
colon cancer 7 | 1,478
group 3 medulloblastoma 7 | 4,104
lung carcinoma 7 | 2,843
Obesity 6 | 678
astrocytic glioma 6 | 2,597
oligodendroglioma 6 | 2,850
pituitary cancer 6 | 1,972
Epilepsy 5 | 792
Pick disease 5 | 1,894
breast carcinoma 5 | 1,638
cystic fibrosis 5 | 1,696
group 4 medulloblastoma 5 | 1,855
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
invasive ductal carcinoma 5 | 2,951
malignant mesothelioma 5 | 3,232
Autistic Disorder 4 | 364
Autosomal recessive predisposition 4 | 1,442
Bipolar Disorder 4 | 666
Cancer 4 | 2,499
Cognitive delay 4 | 608
Global developmental delay 4 | 608
Intellectual disability 4 | 1,016
Mental and motor retardation 4 | 608
Muscle hypotonia 4 | 571
Rheumatoid arthritis 4 | 1,191
Schizophrenia 4 | 1,160
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
subependymal giant cell astrocytoma 4 | 2,287
ulcerative colitis 4 | 1,819
Atopic dermatitis 3 | 952
Autism spectrum disorder 3 | 101
Depressive disorder 3 | 409
Endometrial cancer 3 | 311
Gilles de la Tourette syndrome 3 | 47
Insulin Resistance 3 | 72
Liver cancer 3 | 604
Mental Depression 3 | 333
Nicotine dependence 3 | 54
Parkinson's disease 3 | 392
diabetes mellitus 3 | 1,728
interstitial cystitis 3 | 2,312
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
progressive supranuclear palsy 3 | 676
spina bifida 3 | 1,074
tuberculosis 3 | 2,010
Acquired scoliosis 2 | 281
Advanced bone age 2 | 35
Alzheimer's disease 2 | 658
Breast Neoplasms 2 | 445
Carcinoma, Hepatocellular 2 | 228
Chronic otitis media 2 | 52
Constipation 2 | 181
Crohn's disease 2 | 321
Curvature of spine 2 | 282
Diabetes Mellitus, Non-Insulin-Dependent 2 | 145
Diarrhea 2 | 253
Dyschezia 2 | 135
Hepatomegaly 2 | 285
Hyperinsulinism 2 | 133
Hypertension 2 | 396
Hypothyroidism 2 | 122
Immunologic Deficiency Syndromes 2 | 113
Large intestine cancer 2 | 126
Lung Neoplasms 2 | 232
Mammary Neoplasms 2 | 425
Mood Disorders 2 | 184
Motor neuron disease 2 | 49
Multiple myeloma 2 | 1,332
Pitt-Hopkins syndrome 2 | 20
Systemic lupus erythematosus 2 | 194
Uranostaphyloschisis 2 | 167
Vascular disease 2 | 319
adrenocortical carcinoma 2 | 1,428
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
cutaneous lupus erythematosus 2 | 1,057
cystic fibrosis and chronic rhinosinusitis 2 | 214
ductal carcinoma in situ 2 | 1,745
ear infection chronic 2 | 52
juvenile dermatomyositis 2 | 1,187
lung adenocarcinoma 2 | 2,716
nasopharyngeal carcinoma 2 | 1,058
non-small cell lung cancer 2 | 2,890
pancreatic cancer 2 | 2,398
pancreatic carcinoma 2 | 562
primary Sjogren syndrome 2 | 735

Tissue

Digestive Tract 23 | 17,369
Endocrine System 23 | 18,159
Female tissues 23 | 17,400
Liver and Pancreas 23 | 16,750
Nervous System 23 | 16,725
Skin and soft tissues 23 | 17,230
Urinary Tract 23 | 16,678
Blood and immune system 22 | 16,909
Male tissues 22 | 17,142
Respiratory system 22 | 16,393
Cardiovascular System 20 | 15,192

Target Family

Non-IDG 13 | 12,091
Enzyme 8 | 4,145
Ion Channel 1 | 344
Kinase 1 | 634
Transcription Factor 1 | 1,400

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Beta-1,3-galactosyltransferase 1 B3GALT1 Tbio Enzyme -0.68296 3.85 66
Neurexin-1 NRXN1 Tbio Non-IDG -1.88807 125.1 174
ER membrane protein complex subunit 10 EMC10 Tbio Non-IDG -1.41680 25.5 60
Calcium and integrin-binding protein 1 CIB1 Tbio Non-IDG -2.08897 121.1 264
Potassium voltage-gated channel subfamily B member 1 KCNB1 Tclin Ion Channel -2.57484 386.0 303
Patched domain-containing protein 1 PTCHD1 Tbio Non-IDG -0.84569 7.72 81
Carboxypeptidase E CPE Tbio Enzyme -3.01460 1019.8 229
Leptin receptor LEPR Tclin Non-IDG -3.01833 782.6 615
GRB10-interacting GYF protein 2 GIGYF2 Tchem Non-IDG -1.52965 37.1 43
Leucine-rich repeat serine/threonine-protein kinase 1 LRRK1 Tbio Kinase -1.33128 18.1 134