Development Level

Tbio 13 | 11,445
Tchem 3 | 1,598

IMPC Phenotype

abnormal locomotor activation 16 | 16
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

Carcinoma 13 | 11,493
ependymoma 9 | 4,679
osteosarcoma 9 | 7,950
adult high grade glioma 7 | 3,801
lung cancer 7 | 4,740
ovarian cancer 7 | 8,520
psoriasis 7 | 6,694
glioblastoma 6 | 5,792
group 3 medulloblastoma 6 | 4,104
malignant mesothelioma 6 | 3,232
medulloblastoma, large-cell 6 | 6,241
Astrocytoma, Pilocytic 5 | 3,081
Breast cancer 5 | 3,578
Pick disease 5 | 1,894
atypical teratoid / rhabdoid tumor 5 | 5,112
interstitial cystitis 5 | 2,312
primitive neuroectodermal tumor 5 | 3,035
Kidney cancer 4 | 2,613
astrocytic glioma 4 | 2,597
ductal carcinoma in situ 4 | 1,745
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
non-small cell lung cancer 4 | 2,890
oligodendroglioma 4 | 2,850
pancreatic cancer 4 | 2,398
Melanoma 3 | 711
adrenocortical carcinoma 3 | 1,428
esophageal adenocarcinoma 3 | 737
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
invasive ductal carcinoma 3 | 2,951
lung carcinoma 3 | 2,843
subependymal giant cell astrocytoma 3 | 2,287
Cancer 2 | 2,499
Gamma chain deficiency 2 | 7
Leukemia 2 | 104
MYELODYSPLASTIC SYNDROME 2 | 53
Osteoporosis 2 | 363
Radio-ulnar synostosis-amegakaryocytic thrombocytopenia syndrome 2 | 3
Radioulnar synostosis 2 | 35
Schizophrenia 2 | 1,160
Skin cancer 2 | 469
chronic rhinosinusitis 2 | 512
cystic fibrosis 2 | 1,696
diabetes mellitus 2 | 1,728
lung adenocarcinoma 2 | 2,716
pancreatic carcinoma 2 | 562
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
spina bifida 2 | 1,074
tuberculosis and treatment for 6 months 2 | 409
Acquired metabolic disease 1 | 336
Adult onset 1 | 82
Amegakaryocytic thrombocytopenia 1 | 6
Amyotrophic lateral sclerosis 1 | 451
Atrophy of cerebellum 1 | 103
Autosomal dominant cerebellar ataxia 1 | 33
Barrett's esophagus 1 | 182
Blindness 1 | 88
Breast Neoplasms 1 | 445
Cerebellar degeneration 1 | 103
Cerebellar hypoplasia and atrophy 1 | 41
Cystinosis 1 | 14
Difficulties with night vision 1 | 87
Dizziness 1 | 26
Dyspepsia 1 | 33
Extinguished electroretinogram 1 | 15
Impotence 1 | 42
Infratentorial atrophy 1 | 103
Leber congenital amaurosis 1 | 69
Leukemia, Myeloid 1 | 18
Liver Cirrhosis, Experimental 1 | 769
Lymphoid leukemia 1 | 160
Mammary Neoplasms 1 | 425
Motor delay 1 | 147
Myeloid Leukemia 1 | 19
Myopia 1 | 176
Nasopharyngeal Neoplasms 1 | 9
Neural Tube Defects 1 | 31
Neurodegenerative disease 1 | 414
Night Blindness 1 | 101
No development of motor milestones 1 | 147
Nonsyndromic deafness 1 | 142
Otitis Media 1 | 52
Ovarian Neoplasms 1 | 102
Pancytopenia 1 | 45
Pigmentary iris degeneration 1 | 20
Prenatal onset 1 | 139
Progressive disorder 1 | 142
Retinal blind spot 1 | 11
Scotoma 1 | 22
Sensorineural Hearing Loss (disorder) 1 | 284
Sensorineural hearing loss 1 | 106
Spinocerebellar Ataxias 1 | 34
Usher Syndrome, Type I 1 | 6
Usher Syndrome, Type II 1 | 5
Usher syndrome 1 | 32
Usher syndrome type 2 1 | 5
Vertigo 1 | 29
Vitiligo 1 | 73
facioscapulohumeral dystrophy 1 | 288
ovarian neoplasm 1 | 99

Tissue

Digestive Tract 15 | 17,369
Endocrine System 15 | 18,159
Skin and soft tissues 15 | 17,230
Blood and immune system 14 | 16,909
Female tissues 14 | 17,400
Liver and Pancreas 14 | 16,750
Male tissues 14 | 17,142
Nervous System 14 | 16,725
Respiratory system 14 | 16,393
Urinary Tract 14 | 16,678
Cardiovascular System 13 | 15,192

Target Family

Non-IDG 8 | 12,091
Enzyme 2 | 4,145
Transcription Factor 2 | 1,400
Ion Channel 1 | 344
Kinase 1 | 634
Nuclear Receptor 1 | 48
TF/Epigenetic 1 | 38

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
F-box only protein 11 FBXO11 Tbio Non-IDG -1.53905 34.1 258
Unconventional myosin-VIIa MYO7A Tbio Non-IDG -2.14713 133.5 129
MDS1 and EVI1 complex locus protein MDS1 MECOM Tbio Non-IDG -1.84060 124.5 0
Septin-8 SEPT8 Tbio Non-IDG -1.72470 51.0 171
Homeobox protein HMX3 HMX3 Tbio Transcription Factor -1.18561 14.2 75
Protein NipSnap homolog 1 NIPSNAP1 Tbio Non-IDG -0.79160 7.47 57
Adenylyl cyclase-associated protein 2 CAP2 Tbio Enzyme -0.39794 2.39 125
Nuclear receptor subfamily 1 group D member 2 NR1D2 Tchem Nuclear Receptor -1.77473 57.5 205
Short transient receptor potential channel 3 TRPC3 Tchem Ion Channel -2.46704 294.6 217
LIM domain kinase 2 LIMK2 Tchem Kinase -1.65006 41.3 405