Development Level

Tbio 11 | 11,445
Tchem 3 | 1,598
Tdark 3 | 6,588

IMPC Phenotype

abnormal limb bud morphology 17 | 17
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

Carcinoma 16 | 11,493
ovarian cancer 9 | 8,520
medulloblastoma, large-cell 7 | 6,241
osteosarcoma 7 | 7,950
pancreatic cancer 6 | 2,398
glioblastoma 5 | 5,792
invasive ductal carcinoma 5 | 2,951
lung cancer 5 | 4,740
malignant mesothelioma 5 | 3,232
psoriasis 5 | 6,694
Cancer 4 | 2,499
atypical teratoid / rhabdoid tumor 4 | 5,112
ductal carcinoma in situ 4 | 1,745
ependymoma 4 | 4,679
lung carcinoma 4 | 2,843
spina bifida 4 | 1,074
Breast cancer 3 | 3,578
adult high grade glioma 3 | 3,801
breast carcinoma 3 | 1,638
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
lung adenocarcinoma 3 | 2,716
non-small cell lung cancer 3 | 2,890
pituitary cancer 3 | 1,972
primary pancreatic ductal adenocarcinoma 3 | 1,109
Astrocytoma, Pilocytic 2 | 3,081
Atopic dermatitis 2 | 952
Autosomal recessive predisposition 2 | 1,442
Cerebral calcification 2 | 43
Cerebrovascular disease 2 | 238
Cervical cancer 2 | 24
Epilepsy 2 | 792
Glaucoma 2 | 239
Kidney cancer 2 | 2,613
Klippel-Trenaunay syndrome 2 | 13
Liver Cirrhosis, Experimental 2 | 769
Low compliance bladder 2 | 11
Melanoma 2 | 711
Rheumatoid arthritis 2 | 1,191
Seizures 2 | 596
adrenocortical carcinoma 2 | 1,428
astrocytic glioma 2 | 2,597
astrocytoma 2 | 1,146
diabetes mellitus 2 | 1,728
fibroadenoma 2 | 559
gastric carcinoma 2 | 807
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
medulloblastoma 2 | 720
oligodendroglioma 2 | 2,850
pancreatic carcinoma 2 | 562
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
Acute lymphoid leukemia 1 | 25
Acute necrotizing encephalitis 1 | 2
Amyloidosis 1 | 67
Aortic aneurysm 1 | 38
Basal Cell Nevus Syndrome 1 | 5
Basal cell nevi 1 | 23
Burkitt's lymphoma 1 | 15
Calcification of falx cerebri 1 | 6
Carcinoma of female breast 1 | 20
Cardiac fibroma 1 | 3
Cardiac rhabdomyoma 1 | 5
Cellulitis 1 | 20
Chronic recurrent multifocal osteomyelitis 1 | 6
Congenital Abnormality 1 | 11
Congenital anomaly of neck 1 | 19
Congenital fusion of ribs 1 | 4
Congenital hemolytic anemia 1 | 32
Deformity of neck 1 | 19
Fused vertebrae 1 | 25
Gestational trophoblastic neoplasia 1 | 14
Gorlin syndrome 1 | 4
Hamartomatous stomach polyps 1 | 3
Hemangioma, Cavernous, Central Nervous System 1 | 2
Irregular ossification of hand bones 1 | 3
Juvenile rheumatoid arthritis 1 | 111
Keratocystic Odontogenic Tumor 1 | 3
Malformation of the neck 1 | 19
Malignant tumor of head and/or neck 1 | 15
Milium Cyst 1 | 16
Mycosis fungoides 1 | 29
Non-Hodgkin's lymphoma 1 | 22
Orbital cyst 1 | 8
Ovarian Fibromata 1 | 3
Palmar pit 1 | 4
Parietal bossing 1 | 5
Plantar pits 1 | 4
Psychomotor Disorders 1 | 7
Sella Turcica, Bridged 1 | 3
Short 4th metacarpal 1 | 7
Short ribs 1 | 30
Short thumb terminal phalanx 1 | 5
Skin Abnormalities 1 | 37
Skin tag 1 | 14
Sloping shoulders 1 | 21
Spinal fusion 1 | 25
Sprengel deformity 1 | 16
Sternal anomalies 1 | 19
Vertebral wedging 1 | 4
biotin-responsive basal ganglia disease 1 | 8

Tissue

Blood and immune system 16 | 16,909
Cardiovascular System 16 | 15,192
Digestive Tract 16 | 17,369
Endocrine System 16 | 18,159
Female tissues 16 | 17,400
Liver and Pancreas 16 | 16,750
Male tissues 16 | 17,142
Nervous System 16 | 16,725
Respiratory system 16 | 16,393
Skin and soft tissues 16 | 17,230
Urinary Tract 16 | 16,678

Target Family

Non-IDG 10 | 12,091
Enzyme 4 | 4,145
Ion Channel 1 | 344
Transcription Factor 1 | 1,400
Transporter 1 | 473

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Suppressor of tumorigenicity 14 protein ST14 Tchem Non-IDG -2.50215 338.3 309
Folate receptor alpha FOLR1 Tchem Non-IDG -2.33242 206.1 303
Phosphate carrier protein, mitochondrial SLC25A3 Tbio Transporter -2.85426 703.4 33
Biogenesis of lysosome-related organelles complex 1 subunit 2 BLOC1S2 Tbio Non-IDG -2.89123 759.6 79
Cytochrome c oxidase subunit 7C, mitochondrial COX7C Tdark Enzyme -1.02783 10.1 39
Ras-related protein Rab-34 RAB34 Tbio Enzyme -1.77250 102.9 72
Transmembrane protein 132A TMEM132A Tdark Non-IDG -0.23045 2.47 54
Unconventional myosin-XVIIIa MYO18A Tbio Non-IDG -1.15048 14.2 35
Proprotein convertase subtilisin/kexin type 5 PCSK5 Tchem Enzyme -2.88342 751.2 143
Suppressor of fused homolog SUFU Tbio Non-IDG -2.33544 208.6 168