Development Level

Tbio 46 | 11,445
Tchem 13 | 1,598
Tdark 6 | 6,588

Collection

GPCR: IDG Consortium (Targets) 1 | 126
RFA-RM-18-021 1 | 328

IMPC Phenotype

abnormal kidney morphology 65 | 65
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

Carcinoma 38 | 11,493
ovarian cancer 36 | 8,520
osteosarcoma 30 | 7,950
glioblastoma 26 | 5,792
psoriasis 23 | 6,694
medulloblastoma, large-cell 22 | 6,241
lung cancer 21 | 4,740
atypical teratoid / rhabdoid tumor 20 | 5,112
adult high grade glioma 18 | 3,801
invasive ductal carcinoma 18 | 2,951
ependymoma 17 | 4,679
group 3 medulloblastoma 17 | 4,104
Breast cancer 16 | 3,578
interstitial cystitis 15 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 14 | 3,291
non-small cell lung cancer 14 | 2,890
Cancer 13 | 2,499
intraductal papillary-mucinous adenoma (IPMA) 13 | 2,955
lung carcinoma 13 | 2,843
malignant mesothelioma 13 | 3,232
Astrocytoma, Pilocytic 12 | 3,081
lung adenocarcinoma 12 | 2,716
oligodendroglioma 12 | 2,850
pituitary cancer 12 | 1,972
primitive neuroectodermal tumor 12 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 11 | 2,989
subependymal giant cell astrocytoma 11 | 2,287
astrocytic glioma 10 | 2,597
cutaneous lupus erythematosus 10 | 1,057
pancreatic cancer 10 | 2,398
breast carcinoma 9 | 1,638
ductal carcinoma in situ 9 | 1,745
tuberculosis 9 | 2,010
Kidney cancer 8 | 2,613
ulcerative colitis 8 | 1,819
Intellectual disability 7 | 1,016
Multiple myeloma 7 | 1,332
adrenocortical carcinoma 7 | 1,428
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,962
pediatric high grade glioma 7 | 1,064
Epilepsy 6 | 792
Pick disease 6 | 1,894
cystic fibrosis 6 | 1,696
Autosomal recessive predisposition 5 | 1,442
Dull intelligence 5 | 645
Low intelligence 5 | 645
Mental Retardation 5 | 645
Mental deficiency 5 | 645
Obesity 5 | 678
Poor school performance 5 | 645
Seizures 5 | 596
active Crohn's disease 5 | 922
astrocytoma 5 | 1,146
atypical teratoid/rhabdoid tumor 5 | 357
colon cancer 5 | 1,478
diabetes mellitus 5 | 1,728
group 4 medulloblastoma 5 | 1,855
Asthma 4 | 385
Atopic dermatitis 4 | 952
Cognitive delay 4 | 608
Constipation 4 | 181
Global developmental delay 4 | 608
Mental and motor retardation 4 | 608
esophageal adenocarcinoma 4 | 737
non primary Sjogren syndrome sicca 4 | 891
pancreatic carcinoma 4 | 562
Broad flat nasal bridge 3 | 236
Cholestasis 3 | 155
Conductive hearing loss 3 | 123
Diarrhea 3 | 253
Down syndrome 3 | 499
Endometriosis 3 | 540
Hypogonadism 3 | 173
Liver cancer 3 | 604
Melanoma 3 | 711
Multiple, subcutaneous nodules 3 | 53
Muscle hypotonia 3 | 571
Nasal bridge wide 3 | 236
Neurodegenerative disease 3 | 414
Palmoplantar keratosis 3 | 74
Short stature 3 | 531
Skin cancer 3 | 469
Stomach Neoplasms 3 | 300
Subcutaneous nodule 3 | 53
aldosterone-producing adenoma 3 | 665
fibroadenoma 3 | 559
head and neck cancer and chronic obstructive pulmonary disease 3 | 239
hepatocellular carcinoma 3 | 547
inflammatory breast cancer 3 | 286
posterior fossa group A ependymoma 3 | 468
spina bifida 3 | 1,074
Acquired scoliosis 2 | 281
Anteverted nostril 2 | 191
Concave bridge of nose 2 | 195
Curvature of spine 2 | 282
Depressed nasal bridge 2 | 195
Depressed nasal root/bridge 2 | 195
Kidney disease 2 | 430
active ulcerative colitis 2 | 764
head and neck cancer 2 | 271

Tissue

Digestive Tract 63 | 17,369
Female tissues 62 | 17,400
Male tissues 62 | 17,142
Urinary Tract 62 | 16,678
Endocrine System 61 | 18,159
Nervous System 61 | 16,725
Skin and soft tissues 61 | 17,230
Liver and Pancreas 60 | 16,750
Blood and immune system 59 | 16,909
Respiratory system 59 | 16,393
Cardiovascular System 57 | 15,192

Target Family

Non-IDG 32 | 12,091
Enzyme 16 | 4,145
Transcription Factor 5 | 1,400
GPCR 4 | 408
Epigenetic 3 | 242
Kinase 3 | 634
Nuclear Receptor 1 | 48
Transporter 1 | 473

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Transmembrane protein 160 TMEM160 Tdark Non-IDG 0.38 0.37 10
Cytoglobin CYGB Tbio Non-IDG -3.10582 1269.7 202
Methyltransferase-like 26 METTL26 Tdark Non-IDG 0.00000 58
SID1 transmembrane family member 1 SIDT1 Tbio Non-IDG -1.59973 38.5 125
ATPase family AAA domain-containing protein 2B ATAD2B Tchem Epigenetic 0.27 1.01 18
Folate receptor alpha FOLR1 Tchem Non-IDG -2.33242 206.1 303
NEDD4 family-interacting protein 2 NDFIP2 Tbio Non-IDG -0.67951 5.49 37
Aquaporin-6 AQP6 Tbio Non-IDG -1.52088 32.7 57
Tumor susceptibility gene 101 protein TSG101 Tbio Non-IDG -2.47780 298.9 332
Transmembrane protein 174 TMEM174 Tdark Non-IDG -0.39794 2.90 25