Development Level

Tbio 17 | 10,625
Tchem 9 | 1,890
Tdark 4 | 7,003

IMPC Phenotype

abnormal kidney morphology 30 | 30
preweaning lethality, complete... 633 | 633
preweaning lethality, incomple... 260 | 260
abnormal behavior 226 | 226
decreased lean body mass 195 | 195
embryonic lethality prior to t... 187 | 187
decreased total body fat amoun... 186 | 186
decreased body weight 174 | 174
decreased bone mineral content 157 | 157
embryonic lethality prior to o... 148 | 148
abnormal bone structure 131 | 131
increased or absent threshold ... 128 | 128
decreased bone mineral density 126 | 126
decreased grip strength 123 | 123
decreased circulating glucose ... 121 | 121
increased circulating alkaline... 119 | 119
abnormal embryo size 112 | 112
enlarged heart 111 | 111
decreased body length 108 | 108
hyperactivity 108 | 108
increased lean body mass 107 | 107
abnormal retina morphology 100 | 100
increased mean corpuscular hem... 93 | 93
increased bone mineral content 92 | 92
increased mean corpuscular vol... 91 | 91
hypoactivity 89 | 89
decreased circulating choleste... 85 | 85
decreased circulating triglyce... 83 | 83
increased grip strength 83 | 83
short tibia 82 | 82
decreased circulating serum al... 79 | 79
decreased circulating HDL chol... 77 | 77
decreased circulating insulin ... 75 | 75
abnormal lens morphology 73 | 73
increased circulating sodium l... 71 | 71
increased fasted circulating g... 68 | 68
prenatal lethality prior to he... 64 | 64
abnormal sleep behavior 63 | 63
increased circulating HDL chol... 63 | 63
decreased lumbar vertebrae num... 62 | 62
increased sacral vertebrae num... 62 | 62
male infertility 62 | 62
abnormal retinal pigmentation 61 | 61
decreased rib number 59 | 59
increased total body fat amoun... 57 | 57
improved glucose tolerance 56 | 56
increased exploration in new e... 56 | 56
abnormal bone mineralization 55 | 55
abnormal coat-hair pigmentatio... 54 | 54
decreased leukocyte cell numbe... 54 | 54
decreased circulating alanine ... 53 | 53
decreased hemoglobin content 53 | 53
increased circulating choleste... 53 | 53
abnormal behavioral response t... 52 | 52
decreased prepulse inhibition 52 | 52
impaired glucose tolerance 52 | 52
increased bone mineral density 52 | 52
abnormal gait 51 | 51
abnormal heart morphology 51 | 51
decreased mean corpuscular vol... 50 | 50
decreased caudal vertebrae num... 49 | 49
decreased fasted circulating g... 49 | 49
decreased startle reflex 48 | 48
abnormal seminal vesicle morph... 47 | 47
thrombocytopenia 46 | 46
increased hemoglobin content 45 | 45
decreased heart weight 44 | 44
increased blood urea nitrogen ... 44 | 44
decreased erythrocyte cell num... 43 | 43
increased circulating chloride... 43 | 43
increased body weight 42 | 42
decreased circulating alkaline... 41 | 41
decreased circulating total pr... 41 | 41
decreased eosinophil cell numb... 41 | 41
increased rib number 41 | 41
decreased circulating free fat... 39 | 39
abnormal eye morphology 38 | 38
increased startle reflex 38 | 38
abnormal neural tube closure 37 | 37
decreased circulating LDL chol... 37 | 37
decreased neutrophil cell numb... 37 | 37
increased heart weight 37 | 37
increased leukocyte cell numbe... 37 | 37
small testis 37 | 37
abnormal spleen morphology 36 | 36
increased hematocrit 36 | 36
cardiovascular system phenotyp... 35 | 35
limb grasping 35 | 35
decreased mean corpuscular hem... 34 | 34
female infertility 34 | 34
tremors 34 | 34
decreased circulating calcium ... 33 | 33
abnormal cranium morphology 32 | 32
decreased circulating chloride... 32 | 32
decreased threshold for audito... 32 | 32
increased circulating calcium ... 32 | 32
abnormal epididymis morphology 31 | 31
decreased T cell number 31 | 31
decreased blood urea nitrogen ... 31 | 31
decreased circulating fructosa... 31 | 31
increased circulating potassiu... 31 | 31

Disease

ovarian cancer 16 | 8,491
medulloblastoma, large-cell 14 | 6,234
glioblastoma 13 | 5,572
psoriasis 12 | 6,685
atypical teratoid / rhabdoid tumor 10 | 4,369
osteosarcoma 10 | 7,933
lung cancer 8 | 4,473
primitive neuroectodermal tumor 8 | 3,031
lung adenocarcinoma 7 | 2,714
pediatric high grade glioma 7 | 2,712
Cancer 6 | 2,346
adult high grade glioma 6 | 2,148
breast carcinoma 6 | 1,614
interstitial cystitis 6 | 2,299
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,289
invasive ductal carcinoma 6 | 2,950
non-small cell lung cancer 6 | 2,798
oligodendroglioma 6 | 2,849
pituitary cancer 6 | 1,972
Breast cancer 5 | 3,098
atypical teratoid/rhabdoid tumor 5 | 1,095
ependymoma 5 | 2,514
group 3 medulloblastoma 5 | 2,254
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,795
pilocytic astrocytoma 5 | 3,086
posterior fossa group A ependymoma 5 | 1,511
astrocytic glioma 4 | 2,241
diabetes mellitus 4 | 1,663
ductal carcinoma in situ 4 | 1,745
fibroadenoma 4 | 557
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,988
malignant mesothelioma 4 | 3,163
pancreatic cancer 4 | 2,300
ulcerative colitis 4 | 2,087
Atopic dermatitis 3 | 944
Carcinoma 3 | 2,147
Diarrhea 3 | 155
Obesity 3 | 616
Pick disease 3 | 1,893
adrenocortical carcinoma 3 | 1,427
cutaneous lupus erythematosus 3 | 1,056
esophageal adenocarcinoma 3 | 737
group 4 medulloblastoma 3 | 1,875
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,956
lung carcinoma 3 | 2,844
medulloblastoma 3 | 1,524
non-inflammatory breast cancer 3 | 208
Cholestasis 2 | 93
Constipation 2 | 43
Dental enamel hypoplasia 2 | 12
Down syndrome 2 | 548
Endometriosis 2 | 535
Epilepsy 2 | 346
IGA Glomerulonephritis 2 | 454
Intellectual disability 2 | 573
Multiple myeloma 2 | 1,327
Neurodegenerative disease 2 | 383
Posterior polymorphous corneal dystrophy 2 | 24
Rickets 2 | 42
astrocytoma 2 | 1,493
cystic fibrosis 2 | 1,670
head and neck cancer 2 | 270
nasopharyngeal carcinoma 2 | 1,056
non primary Sjogren syndrome sicca 2 | 840
posterior fossa group B ependymoma 2 | 1,530
progressive supranuclear palsy 2 | 674
subependymal giant cell astrocytoma 2 | 2,287
Acute necrotizing encephalitis 1 | 1
Brain Diseases, Metabolic, Inborn 1 | 4
Choriocarcinoma 1 | 10
Collecting duct carcinoma 1 | 3
Congenital Abnormality 1 | 11
Costello Syndrome 1 | 18
Cowden disease 1 | 20
Dentin dysplasia 1 | 19
Endometritis 1 | 21
Gastrointestinal stromal tumor 1 | 61
Hypochromic anemia 1 | 6
Hypogonadotropic hypogonadism 1 | 20
Hypogonadotropic hypogonadism 7 with or without anosmia 1 | 6
Hypogonadotropism 1 | 9
Idiopathic hypogonadotropic hypogonadism 1 | 9
Klinefelter's syndrome 1 | 59
Liddle syndrome 1 | 14
Malignant mesothelioma of pleura 1 | 7
Malignant tumor of lung 1 | 5
Meningeal Leukemia 1 | 7
Mitochondrial complex II deficiency 1 | 5
Mouth Neoplasms 1 | 44
Neurodegeneration due to cerebral folate transport deficiency 1 | 1
Neurodegenerative syndrome due to cerebral folate transport deficiency 1 | 1
Osteosarcoma of bone 1 | 6
Osteosclerosis 1 | 10
Palmoplantar keratosis 1 | 36
Paraganglioma 1 | 12
Phaeochromocytoma 1 | 20
Postcholecystectomy syndrome 1 | 3
Psychomotor Disorders 1 | 7
Substance abuse 1 | 55
biotin-responsive basal ganglia disease 1 | 8

Tissue

Male tissues 30 | 17,968
Nervous System 30 | 18,560
Cardiovascular System 29 | 17,957
Digestive Tract 29 | 18,472
Endocrine System 29 | 18,511
Female tissues 29 | 18,646
Skin and soft tissues 29 | 18,114
Urinary Tract 29 | 18,443
Blood and immune system 28 | 17,994
Liver and Pancreas 28 | 18,135
Respiratory system 28 | 17,483

Target Family

Non-IDG 12 | 11,969
Enzyme 9 | 4,146
Kinase 3 | 634
Epigenetic 2 | 242
GPCR 2 | 408
Transcription Factor 2 | 1,400

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Folate receptor alpha FOLR1 Tchem Non-IDG -2.27944 181.4 235
Transcription factor GATA-5 GATA5 Tbio Transcription Factor -1.94419 83.7 166
Dentin sialophosphoprotein DSPP Tbio Non-IDG -2.84705 679.6 48
Ephrin type-A receptor 6 EPHA6 Tchem Kinase -1.33373 29.2 223
R-spondin-1 RSPO1 Tbio Non-IDG -2.21541 163.7 143
Poly(U)-specific endoribonuclease ENDOU Tbio Enzyme -1.48326 30.5 31
Zinc finger BED domain-containing protein 4 ZBED4 Tdark Transcription Factor -0.65120 4.10 4
KiSS-1 receptor KISS1R Tchem GPCR -2.42416 253.1 220
V-type proton ATPase subunit d 1 ATP6V0D1 Tbio Enzyme -1.02895 9.11 127
Extracellular serine/threonine protein kinase FAM20C FAM20C Tbio Enzyme -2.29880 192.2 79