Development Level

Tbio 10 | 11,445
Tchem 3 | 1,598

IMPC Phenotype

abnormal iris morphology 13 | 13
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

Carcinoma 10 | 11,493
osteosarcoma 9 | 7,950
ovarian cancer 8 | 8,520
Breast cancer 7 | 3,578
ependymoma 7 | 4,679
glioblastoma 7 | 5,792
medulloblastoma, large-cell 7 | 6,241
Pick disease 6 | 1,894
atypical teratoid / rhabdoid tumor 6 | 5,112
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
psoriasis 6 | 6,694
adult high grade glioma 5 | 3,801
primitive neuroectodermal tumor 5 | 3,035
Kidney cancer 4 | 2,613
astrocytic glioma 4 | 2,597
invasive ductal carcinoma 4 | 2,951
oligodendroglioma 4 | 2,850
pancreatic cancer 4 | 2,398
tuberculosis 4 | 2,010
ulcerative colitis 4 | 1,819
cystic fibrosis 3 | 1,696
ductal carcinoma in situ 3 | 1,745
group 3 medulloblastoma 3 | 4,104
interstitial cystitis 3 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
malignant mesothelioma 3 | 3,232
pancreatic carcinoma 3 | 562
pediatric high grade glioma 3 | 1,064
primary pancreatic ductal adenocarcinoma 3 | 1,109
spina bifida 3 | 1,074
Astrocytoma, Pilocytic 2 | 3,081
Autistic Disorder 2 | 364
Bipolar Disorder 2 | 666
Cancer 2 | 2,499
Decreased platelet count 2 | 111
Depressive disorder 2 | 409
Down syndrome 2 | 499
Epilepsy 2 | 792
Gait abnormality 2 | 135
Hepatomegaly 2 | 285
Hydrolethalus syndrome 2 | 128
Intellectual disability 2 | 1,016
Rheumatoid arthritis 2 | 1,191
Seizures 2 | 596
Thrombocytopenia 2 | 197
Tremor 2 | 113
active ulcerative colitis 2 | 764
adrenocortical carcinoma 2 | 1,428
aldosterone-producing adenoma 2 | 665
breast carcinoma 2 | 1,638
chronic rhinosinusitis 2 | 512
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
juvenile dermatomyositis 2 | 1,187
lung cancer 2 | 4,740
lung carcinoma 2 | 2,843
medulloblastoma 2 | 720
non-small cell lung cancer 2 | 2,890
progressive supranuclear palsy 2 | 676
subependymal giant cell astrocytoma 2 | 2,287
Amblyopia 1 | 38
Blood Coagulation Disorders 1 | 42
Breast Neoplasms 1 | 445
Chediak-Higashi syndrome 1 | 26
Coagulation abnormalities 1 | 27
Colorectal Neoplasms 1 | 243
Congenital disorder of glycosylation 1 | 54
Congenital heart disease 1 | 93
Decreased nerve conduction velocity 1 | 35
Ecchymosis 1 | 66
Epistaxis 1 | 43
Gingival Hemorrhage 1 | 18
Griscelli syndrome type 2 1 | 12
Hemorrhagic Disorders 1 | 30
Hermansky-Pudlak syndrome 1 | 42
Hyperphosphatemia 1 | 32
Hypophosphatemia 1 | 40
Hypopigmentation disorder 1 | 25
Immunologic Deficiency Syndromes 1 | 113
Increased tendency to bruise 1 | 66
Lymphadenopathy 1 | 62
Lymphoma 1 | 81
Lymphopenia 1 | 67
Mammary Neoplasms 1 | 425
Mental deterioration 1 | 32
Nerve Degeneration 1 | 121
Neuro-degenerative disease 1 | 43
Neurodegenerative Disorders 1 | 79
Neutrophil count decreased 1 | 47
Oculocutaneous albinism 1 | 29
Paresthesia 1 | 32
Peripheral Neuropathy 1 | 134
Photodysphoria 1 | 121
Photophobia 1 | 121
Pigment dispersion syndrome 1 | 11
Pigmentary iris degeneration 1 | 20
Platelet storage pool deficiency 1 | 21
Progressive peripheral neuropathy 1 | 3
Recurrent respiratory infections 1 | 141
Urinary Incontinence 1 | 50
lingual-facial-buccal dyskinesia 1 | 13

Tissue

Blood and immune system 13 | 16,909
Cardiovascular System 13 | 15,192
Digestive Tract 13 | 17,369
Endocrine System 13 | 18,159
Female tissues 13 | 17,400
Liver and Pancreas 13 | 16,750
Male tissues 13 | 17,142
Nervous System 13 | 16,725
Respiratory system 13 | 16,393
Skin and soft tissues 13 | 17,230
Urinary Tract 13 | 16,678

Target Family

Non-IDG 8 | 12,091
Enzyme 2 | 4,145
Epigenetic 1 | 242
Nuclear Receptor 1 | 48
Transporter 1 | 473

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Transmembrane protein 165 TMEM165 Tbio Non-IDG -1.56011 39.2 89
Lysosomal-trafficking regulator LYST Tbio Non-IDG -1.96473 92.5 15
Protein spinster homolog 2 SPNS2 Tbio Non-IDG -1.42853 26.4 88
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 AGAP1 Tbio Enzyme -0.83079 8.71 94
Sodium-dependent phosphate transporter 2 SLC20A2 Tbio Transporter -2.29276 197.3 107
Cytochrome b561 CYB561 Tbio Non-IDG -1.41422 21.1 62
Coiled-coil domain-containing protein R3HCC1L R3HCC1L Tbio Non-IDG -1.17689 12.7 71
Cysteine-rich protein 2-binding protein KAT14 Tbio Non-IDG -0.90082 7.81 111
Nuclear receptor subfamily 1 group D member 2 NR1D2 Tchem Nuclear Receptor -1.77473 57.5 205
Abl interactor 2 ABI2 Tbio Non-IDG -1.37075 21.4 168