Development Level

Tbio 9 | 11,445
Tchem 2 | 1,598

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

abnormal humerus morphology 11 | 11
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

Carcinoma 7 | 11,493
glioblastoma 7 | 5,792
Astrocytoma, Pilocytic 5 | 3,081
ependymoma 5 | 4,679
lung cancer 5 | 4,740
malignant mesothelioma 5 | 3,232
osteosarcoma 5 | 7,950
ovarian cancer 5 | 8,520
atypical teratoid / rhabdoid tumor 4 | 5,112
invasive ductal carcinoma 4 | 2,951
juvenile dermatomyositis 4 | 1,187
medulloblastoma, large-cell 4 | 6,241
primitive neuroectodermal tumor 4 | 3,035
Autosomal recessive predisposition 3 | 1,442
Cancer 3 | 2,499
Duchenne muscular dystrophy 3 | 601
active Crohn's disease 3 | 922
adult high grade glioma 3 | 3,801
group 4 medulloblastoma 3 | 1,855
limb girdle muscular dystrophy 2A 3 | 213
psoriasis 3 | 6,694
ulcerative colitis 3 | 1,819
Becker muscular dystrophy 2 | 191
Degenerative disc disease 2 | 35
Genu varum 2 | 29
Kidney cancer 2 | 2,613
Liver Cirrhosis, Experimental 2 | 769
Motor delay 2 | 147
Multiple Sclerosis 2 | 540
Muscle hypotonia 2 | 571
No development of motor milestones 2 | 147
Pick disease 2 | 1,894
Short stature 2 | 531
active ulcerative colitis 2 | 764
adrenocortical carcinoma 2 | 1,428
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
colon cancer 2 | 1,478
cystic fibrosis 2 | 1,696
esophageal adenocarcinoma 2 | 737
gastric carcinoma 2 | 807
interstitial cystitis 2 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
pancreatic cancer 2 | 2,398
primary pancreatic ductal adenocarcinoma 2 | 1,109
subependymal giant cell astrocytoma 2 | 2,287
urothelial carcinoma 2 | 318
Addison's disease 1 | 31
Cholangitis 1 | 32
Cholestasis, Extrahepatic 1 | 25
Collapse of vertebra 1 | 14
Compression fracture of vertebral column 1 | 14
Congenital hypothyroidism 1 | 26
Decreased muscle mass 1 | 28
Delayed epiphyseal ossification 1 | 10
Delayed maturation of end part of long bone 1 | 10
Enlargement of the costochondral junction 1 | 4
Female Urogenital Diseases 1 | 18
Femoral bowing 1 | 20
Fibular bowing 1 | 5
Goiter 1 | 38
Heart Diseases 1 | 43
Heart Valve Diseases 1 | 25
Hepatitis 1 | 67
Hepatolenticular Degeneration 1 | 24
Hypermobility syndrome 1 | 17
Increased serum parathyroid hormone 1 | 14
Irregular epiphyses 1 | 10
Irregular vertebral endplates 1 | 16
Irritation - emotion 1 | 68
MICROCEPHALY, PRIMARY AUTOSOMAL RECESSIVE, 1 1 | 16
Metaphyseal dysplasia 1 | 11
Metaphyseal irregularity 1 | 23
Microcephalic osteodysplastic primordial dwarfism type II 1 | 13
Microcephaly, Primary Autosomal Recessive, 6 1 | 1
Neoplasms, Experimental 1 | 40
Nocardiosis 1 | 6
Oral Submucous Fibrosis 1 | 20
Osteoblastoma 1 | 8
Osteochondritis dissecans 1 | 17
Osteogenesis imperfecta type IV (disorder) 1 | 10
Penile cancer 1 | 3
Platyspondyly 1 | 56
Primary autosomal recessive microcephaly 6 1 | 1
Pulmonary Fibrosis 1 | 106
Relative short stature 1 | 13
Respiratory Distress Syndrome, Adult 1 | 40
Retinal disease 1 | 25
SECKEL SYNDROME 4 1 | 1
Severe myopia 1 | 22
Short hands 1 | 50
Short stature, mild 1 | 13
Sick sinus syndrome 1 | 15
Tibial bowing 1 | 19
Uremia 1 | 19
Ureteral obstruction 1 | 33
Varicosity 1 | 12
Widely patent fontanels and sutures 1 | 12
osteogenesis imperfecta type 4 1 | 10

Tissue

Blood and immune system 11 | 16,909
Digestive Tract 11 | 17,369
Endocrine System 11 | 18,159
Female tissues 11 | 17,400
Liver and Pancreas 11 | 16,750
Male tissues 11 | 17,142
Skin and soft tissues 11 | 17,230
Urinary Tract 11 | 16,678
Nervous System 10 | 16,725
Respiratory system 10 | 16,393
Cardiovascular System 9 | 15,192

Target Family

Non-IDG 5 | 12,091
Enzyme 4 | 4,145
Kinase 1 | 634
Transcription Factor 1 | 1,400

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Centromere protein J CENPJ Tbio Non-IDG -1.79588 59.0 102
Leucine-rich repeat serine/threonine-protein kinase 1 LRRK1 Tbio Kinase -1.33128 18.1 134
Fas-binding factor 1 FBF1 Tbio Non-IDG 0.00000 27
Protein FAM92A FAM92A Tbio Non-IDG -0.79005 6.14 92
Metalloproteinase inhibitor 1 TIMP1 Tbio Enzyme -3.57247 3714.8 810
Dual specificity protein phosphatase 3 DUSP3 Tchem Enzyme -2.11925 133.6 222
25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial CYP27B1 Tchem Enzyme -2.70628 492.9 68
SPARC SPARC Tbio Non-IDG -3.10194 1136.1 543
snRNA-activating protein complex subunit 4 SNAPC4 Tbio Transcription Factor -0.99715 10.0 160
Dual oxidase maturation factor 2 DUOXA2 Tbio Enzyme -1.35199 19.7 84