Development Level

Tbio 7 | 11,445
Tchem 2 | 1,598
Tdark 1 | 6,588

IMPC Phenotype

abnormal hindbrain morphology 10 | 10
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

Carcinoma 4 | 11,493
group 3 medulloblastoma 4 | 4,104
medulloblastoma, large-cell 4 | 6,241
ovarian cancer 4 | 8,520
Breast cancer 3 | 3,578
ependymoma 3 | 4,679
esophageal adenocarcinoma 3 | 737
lung adenocarcinoma 3 | 2,716
lung cancer 3 | 4,740
osteosarcoma 3 | 7,950
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
primitive neuroectodermal tumor 3 | 3,035
psoriasis 3 | 6,694
Cancer 2 | 2,499
DiGeorge syndrome 2 | 47
Microphthalmia 2 | 76
Velocardiofacial syndrome 2 | 46
acute myeloid leukemia 2 | 783
astrocytoma 2 | 1,146
atypical teratoid / rhabdoid tumor 2 | 5,112
breast carcinoma 2 | 1,638
colon cancer 2 | 1,478
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
invasive ductal carcinoma 2 | 2,951
nephrosclerosis 2 | 333
non-small cell lung cancer 2 | 2,890
oligodendroglioma 2 | 2,850
pancreatic cancer 2 | 2,398
pituitary cancer 2 | 1,972
tuberculosis 2 | 2,010
Abnormal blistering of the skin 1 | 54
Acrodermatitis enteropathica 1 | 18
Alopecia 1 | 115
Baller-Gerold syndrome 1 | 12
Bladder exstrophy 1 | 32
Blister of skin 1 | 54
Cerebral atrophy 1 | 178
Chromosome 22q11.2 microduplication syndrome 1 | 8
Ciliary Motility Disorders 1 | 38
Coloboma 1 | 51
Common variable immunodeficiency 1 | 101
Congenital heart disease 1 | 93
Conjunctivitis 1 | 53
Conjunctivitis, recurrent 1 | 37
Decreased testosterone in males 1 | 28
Dermatitis 1 | 157
Diarrhea 1 | 253
Dry skin 1 | 75
Erythema 1 | 58
Failure to gain weight 1 | 365
Familial Mediterranean fever 1 | 13
Fanconi syndrome 1 | 14
Flushing 1 | 60
Fundus dystrophy 1 | 83
Glossitis 1 | 4
HIV Infections 1 | 102
Hepatomegaly 1 | 285
Hirschsprung's disease 1 | 46
Hypospadias 1 | 53
Impaired T cell function 1 | 14
Imperforate anus 1 | 25
Infantile onset 1 | 238
Irritation - emotion 1 | 68
Kidney Neoplasms 1 | 37
Lethargy 1 | 77
Liver Cirrhosis, Experimental 1 | 769
Liver cancer 1 | 604
Malabsorption 1 | 82
Microcephaly 1 | 166
Mood swings 1 | 77
Mulibrey nanism 1 | 13
Nager acrofacial dysostosis 1 | 21
Neoplasm Metastasis 1 | 168
Neural Tube Defects 1 | 31
Oculocerebrorenal syndrome 1 | 29
Oligospermia 1 | 36
Opitz-GBBB syndrome 1 | 18
Paronychia Inflammation 1 | 9
Pediatric failure to thrive 1 | 365
Photodysphoria 1 | 121
Photophobia 1 | 121
Pimples 1 | 10
Prenatal Injuries 1 | 11
Respiratory Hypersensitivity 1 | 19
Ridged nails 1 | 14
Skin Ulcer 1 | 48
Skin bulla 1 | 54
Skin tag 1 | 14
Small testicle 1 | 75
Treacher Collins syndrome 1 | 27
Tremor 1 | 113
Xerosis 1 | 75
glioblastoma multiforme 1 | 142
neural tube defect 1 | 9
pediatric high grade glioma 1 | 1,064
posterior fossa group A ependymoma 1 | 468
pustule 1 | 10
tuberculosis and treatment for 3 months 1 | 179

Tissue

Blood and immune system 10 | 16,909
Digestive Tract 10 | 17,369
Endocrine System 10 | 18,159
Female tissues 10 | 17,400
Liver and Pancreas 10 | 16,750
Male tissues 10 | 17,142
Nervous System 10 | 16,725
Respiratory system 10 | 16,393
Skin and soft tissues 10 | 17,230
Urinary Tract 10 | 16,678
Cardiovascular System 8 | 15,192

Target Family

Enzyme 4 | 4,145
Non-IDG 3 | 12,091
Epigenetic 2 | 242
Transporter 1 | 473

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Lysosomal-associated transmembrane protein 4B LAPTM4B Tbio Non-IDG -1.90763 86.1 91
Cat eye syndrome critical region protein 2 CECR2 Tchem Epigenetic -2.17030 147.0 44
Anaphase-promoting complex subunit 15 ANAPC15 Tdark Enzyme -0.41378 2.22 27
Ran-specific GTPase-activating protein RANBP1 Tbio Enzyme -1.80548 64.8 193
Pygopus homolog 2 PYGO2 Tbio Epigenetic -1.26911 24.4 92
Zinc transporter ZIP4 SLC39A4 Tbio Transporter -2.05142 112.2 124
72 kDa inositol polyphosphate 5-phosphatase INPP5E Tbio Enzyme -1.47845 28.1 63
Gamma-butyrobetaine dioxygenase BBOX1 Tchem Enzyme -2.54972 300.7 253
Protein scribble homolog SCRIB Tbio Non-IDG -1.79333 61.7 94
Sorting nexin-3 SNX3 Tbio Non-IDG -1.34230 23.5 225