Development Level

Tbio 102 | 11,445
Tdark 31 | 6,588
Tchem 22 | 1,598
Tclin 7 | 613

Collection

RFA-RM-18-021 2 | 328
GPCR: IDG Consortium (Complete... 1 | 25
GPCR: IDG Consortium (Targets) 1 | 126
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

abnormal heart morphology 162 | 162
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

Carcinoma 92 | 11,493
ovarian cancer 86 | 8,520
psoriasis 70 | 6,694
osteosarcoma 65 | 7,950
medulloblastoma, large-cell 57 | 6,241
lung cancer 50 | 4,740
glioblastoma 43 | 5,792
atypical teratoid / rhabdoid tumor 42 | 5,112
intraductal papillary-mucinous adenoma (IPMA) 37 | 2,955
lung carcinoma 37 | 2,843
non-small cell lung cancer 37 | 2,890
Breast cancer 36 | 3,578
Cancer 35 | 2,499
group 3 medulloblastoma 34 | 4,104
ependymoma 33 | 4,679
adult high grade glioma 32 | 3,801
invasive ductal carcinoma 32 | 2,951
lung adenocarcinoma 32 | 2,716
intraductal papillary-mucinous neoplasm (IPMN) 31 | 3,291
malignant mesothelioma 30 | 3,232
pituitary cancer 28 | 1,972
interstitial cystitis 27 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 27 | 2,989
oligodendroglioma 27 | 2,850
group 4 medulloblastoma 26 | 1,855
pancreatic cancer 25 | 2,398
ductal carcinoma in situ 24 | 1,745
adrenocortical carcinoma 23 | 1,428
tuberculosis 23 | 2,010
ulcerative colitis 22 | 1,819
subependymal giant cell astrocytoma 21 | 2,287
pancreatic ductal adenocarcinoma liver metastasis 20 | 1,962
Pick disease 19 | 1,894
astrocytic glioma 19 | 2,597
breast carcinoma 19 | 1,638
primitive neuroectodermal tumor 19 | 3,035
Astrocytoma, Pilocytic 18 | 3,081
Schizophrenia 18 | 1,160
Autosomal recessive predisposition 17 | 1,442
Kidney cancer 17 | 2,613
Rheumatoid arthritis 17 | 1,191
colon cancer 17 | 1,478
cystic fibrosis 17 | 1,696
diabetes mellitus 16 | 1,728
Atopic dermatitis 13 | 952
cutaneous lupus erythematosus 13 | 1,057
acute quadriplegic myopathy 12 | 1,158
primary pancreatic ductal adenocarcinoma 12 | 1,109
Intellectual disability 11 | 1,016
active Crohn's disease 11 | 922
nasopharyngeal carcinoma 11 | 1,058
Epilepsy 10 | 792
non primary Sjogren syndrome sicca 10 | 891
primary Sjogren syndrome 10 | 735
Bipolar Disorder 9 | 666
Liver Cirrhosis, Experimental 9 | 769
Melanoma 9 | 711
Obesity 9 | 678
astrocytoma 9 | 1,146
pancreatic carcinoma 9 | 562
Endometriosis 8 | 540
Multiple myeloma 8 | 1,332
Neurodegenerative disease 8 | 414
active ulcerative colitis 8 | 764
chronic rhinosinusitis 8 | 512
gastric carcinoma 8 | 807
Acquired metabolic disease 7 | 336
Asthma 7 | 385
Multiple Sclerosis 7 | 540
Prostatic Neoplasms 7 | 495
Seizures 7 | 596
acute myeloid leukemia 7 | 783
aldosterone-producing adenoma 7 | 665
fibroadenoma 7 | 559
head and neck cancer 7 | 271
hepatocellular carcinoma 7 | 547
spina bifida 7 | 1,074
Dull intelligence 6 | 645
Kidney disease 6 | 430
Low intelligence 6 | 645
Mental Retardation 6 | 645
Mental deficiency 6 | 645
Muscle hypotonia 6 | 571
Poor school performance 6 | 645
adrenocortical adenoma 6 | 131
periodontitis 6 | 293
posterior fossa group A ependymoma 6 | 468
Cataract 5 | 297
Cognitive delay 5 | 608
Global developmental delay 5 | 608
Hypersensitivity reaction type II disease 5 | 253
Mental and motor retardation 5 | 608
Nystagmus 5 | 317
atypical teratoid/rhabdoid tumor 5 | 357
autosomal dominant Emery-Dreifuss muscular dystrophy 5 | 510
esophageal adenocarcinoma 5 | 737
gastric cancer 5 | 459
juvenile dermatomyositis 5 | 1,187
mucosa-associated lymphoid tissue lymphoma 5 | 484
sonic hedgehog group medulloblastoma 5 | 467

Tissue

Endocrine System 159 | 18,159
Urinary Tract 158 | 16,678
Digestive Tract 157 | 17,369
Male tissues 157 | 17,142
Blood and immune system 156 | 16,909
Female tissues 156 | 17,400
Skin and soft tissues 154 | 17,230
Respiratory system 152 | 16,393
Liver and Pancreas 151 | 16,750
Nervous System 149 | 16,725
Cardiovascular System 139 | 15,192

Target Family

Non-IDG 85 | 12,091
Enzyme 44 | 4,145
Transcription Factor 11 | 1,400
GPCR 8 | 408
Ion Channel 4 | 344
Kinase 4 | 634
Transporter 3 | 473
Nuclear Receptor 2 | 48
Epigenetic 1 | 242

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Anaphase-promoting complex subunit 4 ANAPC4 Tbio Enzyme 0.43 0.13 156
Phosphate carrier protein, mitochondrial SLC25A3 Tbio Transporter -2.85426 703.4 33
Transmembrane protein 160 TMEM160 Tdark Non-IDG 0.38 0.37 10
Cytoglobin CYGB Tbio Non-IDG -3.10582 1269.7 202
Poly(A) RNA polymerase, mitochondrial MTPAP Tbio Enzyme -1.36829 24.0 68
Nucleoside diphosphate-linked moiety X motif 19 NUDT19 Tdark Non-IDG 0.90 0.09 79
Progesterone-induced-blocking factor 1 PIBF1 Tbio Non-IDG -1.30666 21.1 209
Protein FAM151A FAM151A Tdark Non-IDG 0.00000 63
Folate receptor alpha FOLR1 Tchem Non-IDG -2.33242 206.1 303
Putative ADP-ribosylation factor-like protein 5C ARL5C Tdark Enzyme 0.00000 1.00 39