Development Level

Tbio 5 | 11,445
Tdark 4 | 6,588
Tchem 1 | 1,598

IMPC Phenotype

abnormal head shape 10 | 10
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

ovarian cancer 8 | 8,520
Carcinoma 7 | 11,493
osteosarcoma 7 | 7,950
glioblastoma 5 | 5,792
medulloblastoma, large-cell 5 | 6,241
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
Kidney cancer 3 | 2,613
adult high grade glioma 3 | 3,801
astrocytoma 3 | 1,146
atypical teratoid / rhabdoid tumor 3 | 5,112
group 3 medulloblastoma 3 | 4,104
lung cancer 3 | 4,740
Barrett's esophagus 2 | 182
Breast cancer 2 | 3,578
Cleft Palate 2 | 271
Colorectal Neoplasms 2 | 243
Rheumatoid arthritis 2 | 1,191
acute myeloid leukemia 2 | 783
acute quadriplegic myopathy 2 | 1,158
adrenocortical carcinoma 2 | 1,428
astrocytic glioma 2 | 2,597
breast carcinoma 2 | 1,638
cystic fibrosis 2 | 1,696
dermatomyositis 2 | 966
esophageal adenocarcinoma 2 | 737
gastric carcinoma 2 | 807
interstitial cystitis 2 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
invasive ductal carcinoma 2 | 2,951
lung adenocarcinoma 2 | 2,716
lung carcinoma 2 | 2,843
malignant mesothelioma 2 | 3,232
non-small cell lung cancer 2 | 2,890
oligodendroglioma 2 | 2,850
pituitary cancer 2 | 1,972
subependymal giant cell astrocytoma 2 | 2,287
ulcerative colitis 2 | 1,819
Abnormality of the fingernails 1 | 51
Acquired immunodeficiency syndrome 1 | 197
Amyotrophic neuralgia 1 | 13
Anodontia 1 | 12
Birthmark 1 | 35
Brachydactyly 1 | 156
Brain hemorrhage 1 | 14
Cafe-au-Lait Spots 1 | 37
Carcinoma of colon 1 | 32
Cerebral Hemorrhage 1 | 42
Charcot-Marie-Tooth disease 1 | 62
Decreased motor NCV 1 | 22
Decreased projection of maxilla 1 | 66
Decreased projection of midface 1 | 105
Decreased size of teeth 1 | 62
Decreased width of tooth 1 | 59
Deficiency of upper jaw bones 1 | 66
Elevated heart rate 1 | 25
Elevated urinary norepinephrine 1 | 5
Familial adenomatous polyposis 1 | 32
Fatty liver disease 1 | 103
Fibular hypoplasia 1 | 9
Hemangioma 1 | 69
Hooked clavicle 1 | 5
Hypercalcemia 1 | 59
Hypertension, episodic 1 | 5
Hypertensive Retinopathy 1 | 14
Hypodontia 1 | 81
Hypohidrotic ectodermal dysplasia 1 | 15
Hypoplasia of the maxilla 1 | 66
Hypoplastic toenails 1 | 22
Hypotrophic malar bone 1 | 129
Hypotrophic maxilla 1 | 66
Hypotrophic midface 1 | 105
Increased fibular diameter 1 | 4
Increased sweating 1 | 81
Lymphatic obstruction 1 | 21
Malar flattening 1 | 129
Maxillary retrognathia 1 | 66
Microdontia (disorder) 1 | 59
Microphthalmia 1 | 76
Midface retrusion 1 | 105
Narrow thorax 1 | 53
Oligodontia 1 | 24
Onset of lymphedema around puberty 1 | 21
Paraganglioma 1 | 15
Pheochromocytoma 1 | 24
Positive regitine blocking test 1 | 5
Renal Artery Stenosis 1 | 9
Renal Cell Carcinoma 1 | 214
Retrusion of upper jaw bones 1 | 66
Robinow syndrome 1 | 11
Sezary's disease 1 | 15
Short limb dwarfism, disproportionate 1 | 22
Short ribs 1 | 30
Small midface 1 | 105
Stillbirth 1 | 17
Sweating 1 | 81
Tooth agenesis 1 | 44
Transitional cell carcinoma of bladder 1 | 17
inflammatory breast cancer 1 | 286
interstitial lung disease 1 | 298

Tissue

Blood and immune system 10 | 16,909
Cardiovascular System 10 | 15,192
Digestive Tract 10 | 17,369
Endocrine System 10 | 18,159
Female tissues 10 | 17,400
Liver and Pancreas 10 | 16,750
Male tissues 10 | 17,142
Nervous System 10 | 16,725
Respiratory system 10 | 16,393
Skin and soft tissues 10 | 17,230
Urinary Tract 10 | 16,678

Target Family

Non-IDG 6 | 12,091
Enzyme 1 | 4,145
Kinase 1 | 634
Transcription Factor 1 | 1,400
Transporter 1 | 473

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Nucleoredoxin NXN Tbio Non-IDG -2.54390 345.4 96
Anaphase-promoting complex subunit 15 ANAPC15 Tdark Enzyme -0.41378 2.22 27
Transmembrane protein 132A TMEM132A Tdark Non-IDG -0.23045 2.47 54
Basic helix-loop-helix domain-containing protein USF3 USF3 Tdark Transcription Factor -0.08389 1.16 14
UDP-glucuronic acid/UDP-N-acetylgalactosamine transporter SLC35D1 Tbio Transporter -0.77614 5.86 105
Axin-2 AXIN2 Tchem Non-IDG -2.44870 241.5 237
Tribbles homolog 1 TRIB1 Tbio Kinase -1.74370 59.4 250
GATOR complex protein WDR59 WDR59 Tdark Non-IDG 0.01 0.25 35
Sorting nexin-3 SNX3 Tbio Non-IDG -1.34230 23.5 225
Kinesin-like protein KIF1B KIF1B Tbio Non-IDG -2.08306 118.0 60