Development Level

Tbio 12 | 11,445
Tchem 2 | 1,598
Tdark 2 | 6,588
Tclin 1 | 613

IMPC Phenotype

abnormal facial morphology 17 | 17
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

Carcinoma 15 | 11,493
ovarian cancer 12 | 8,520
osteosarcoma 10 | 7,950
glioblastoma 8 | 5,792
lung cancer 7 | 4,740
atypical teratoid / rhabdoid tumor 6 | 5,112
ependymoma 6 | 4,679
medulloblastoma, large-cell 6 | 6,241
Breast cancer 5 | 3,578
ductal carcinoma in situ 5 | 1,745
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
Astrocytoma, Pilocytic 4 | 3,081
Kidney cancer 4 | 2,613
Rheumatoid arthritis 4 | 1,191
adrenocortical carcinoma 4 | 1,428
adult high grade glioma 4 | 3,801
astrocytic glioma 4 | 2,597
group 3 medulloblastoma 4 | 4,104
interstitial cystitis 4 | 2,312
invasive ductal carcinoma 4 | 2,951
malignant mesothelioma 4 | 3,232
pituitary cancer 4 | 1,972
Cancer 3 | 2,499
Cleft Palate 3 | 271
astrocytoma 3 | 1,146
breast carcinoma 3 | 1,638
cystic fibrosis 3 | 1,696
gastric carcinoma 3 | 807
group 4 medulloblastoma 3 | 1,855
non-small cell lung cancer 3 | 2,890
oligodendroglioma 3 | 2,850
primary pancreatic ductal adenocarcinoma 3 | 1,109
psoriasis 3 | 6,694
ulcerative colitis 3 | 1,819
Amyotrophic lateral sclerosis 2 | 451
Anodontia 2 | 12
Barrett's esophagus 2 | 182
Cervical cancer 2 | 24
Cleft Lip 2 | 141
Colorectal Neoplasms 2 | 243
Craniofacial Abnormalities 2 | 151
Decreased projection of maxilla 2 | 66
Decreased size of teeth 2 | 62
Decreased tendon reflex 2 | 122
Decreased width of tooth 2 | 59
Deficiency of upper jaw bones 2 | 66
Hyperhidrosis disorder 2 | 81
Hypodontia 2 | 81
Hypohidrotic ectodermal dysplasia 2 | 15
Hypoplasia of the maxilla 2 | 66
Hypoplastic mandible condyle 2 | 275
Hypoplastic toenails 2 | 22
Hypotrophic maxilla 2 | 66
Increased sweating 2 | 81
Low compliance bladder 2 | 11
Mandibular hypoplasia 2 | 275
Maxillary retrognathia 2 | 66
Melanoma 2 | 711
Microdontia (disorder) 2 | 59
Micrognathism 2 | 275
Missing more than six teeth 2 | 22
Multiple Sclerosis 2 | 540
Oligodontia 2 | 24
Pick disease 2 | 1,894
Retrusion of upper jaw bones 2 | 66
Stomach Neoplasms 2 | 300
Sweating 2 | 81
Tooth agenesis 2 | 44
Uranostaphyloschisis 2 | 167
acute myeloid leukemia 2 | 783
acute quadriplegic myopathy 2 | 1,158
atypical teratoid/rhabdoid tumor 2 | 357
chronic rhinosinusitis 2 | 512
dermatomyositis 2 | 966
esophageal adenocarcinoma 2 | 737
fibroadenoma 2 | 559
glioblastoma multiforme 2 | 142
lung adenocarcinoma 2 | 2,716
lung carcinoma 2 | 2,843
nasopharyngeal carcinoma 2 | 1,058
non primary Sjogren syndrome sicca 2 | 891
primitive neuroectodermal tumor 2 | 3,035
spina bifida 2 | 1,074
subependymal giant cell astrocytoma 2 | 2,287
Amyotrophic neuralgia 1 | 13
Birthmark 1 | 35
Cafe-au-Lait Spots 1 | 37
Elevated heart rate 1 | 25
Elevated urinary norepinephrine 1 | 5
Hereditary nonpolyposis colorectal carcinoma 1 | 18
Hypertension, episodic 1 | 5
Increased gastric cancer 1 | 21
Leiomyosarcoma of uterus 1 | 13
Micronychia (disorder) 1 | 24
Polyneuropathy 1 | 64
Positive regitine blocking test 1 | 5
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 1 | 25
Transitional cell carcinoma of bladder 1 | 17

Tissue

Blood and immune system 16 | 16,909
Digestive Tract 16 | 17,369
Endocrine System 16 | 18,159
Female tissues 16 | 17,400
Male tissues 16 | 17,142
Nervous System 16 | 16,725
Respiratory system 16 | 16,393
Skin and soft tissues 16 | 17,230
Urinary Tract 16 | 16,678
Liver and Pancreas 15 | 16,750
Cardiovascular System 14 | 15,192

Target Family

Non-IDG 7 | 12,091
Transcription Factor 4 | 1,400
Enzyme 3 | 4,145
Ion Channel 1 | 344
Kinase 1 | 634
Transporter 1 | 473

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Kinesin-like protein KIF1B KIF1B Tbio Non-IDG -2.08306 118.0 60
Axin-2 AXIN2 Tchem Non-IDG -2.44870 241.5 237
Homeobox protein MSX-1 MSX1 Tbio Transcription Factor -2.59245 390.1 298
Proprotein convertase subtilisin/kexin type 5 PCSK5 Tchem Enzyme -2.88342 751.2 143
Nucleoside diphosphate kinase 7 NME7 Tbio Enzyme -0.83479 6.29 113
Tribbles homolog 1 TRIB1 Tbio Kinase -1.74370 59.4 250
Sorting nexin-3 SNX3 Tbio Non-IDG -1.34230 23.5 225
B-cell lymphoma/leukemia 11B BCL11B Tbio Transcription Factor -2.10918 140.4 186
Exportin-T XPOT Tbio Non-IDG -1.46210 29.6 86
GA-binding protein alpha chain GABPA Tbio Transcription Factor -1.50283 31.7 289