Development Level

Tbio 52 | 11,445
Tchem 8 | 1,598
Tdark 6 | 6,588
Tclin 2 | 613

IMPC Phenotype

abnormal eye morphology 68 | 68
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

Carcinoma 43 | 11,493
ovarian cancer 36 | 8,520
lung cancer 30 | 4,740
medulloblastoma, large-cell 30 | 6,241
osteosarcoma 29 | 7,950
glioblastoma 25 | 5,792
psoriasis 24 | 6,694
atypical teratoid / rhabdoid tumor 22 | 5,112
ependymoma 21 | 4,679
lung adenocarcinoma 18 | 2,716
primitive neuroectodermal tumor 18 | 3,035
adult high grade glioma 17 | 3,801
group 3 medulloblastoma 17 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 17 | 3,291
oligodendroglioma 17 | 2,850
Astrocytoma, Pilocytic 16 | 3,081
invasive ductal carcinoma 16 | 2,951
non-small cell lung cancer 15 | 2,890
lung carcinoma 14 | 2,843
Kidney cancer 13 | 2,613
astrocytic glioma 13 | 2,597
intraductal papillary-mucinous adenoma (IPMA) 13 | 2,955
malignant mesothelioma 13 | 3,232
pancreatic cancer 13 | 2,398
Breast cancer 12 | 3,578
Pick disease 12 | 1,894
intraductal papillary-mucinous carcinoma (IPMC) 12 | 2,989
cystic fibrosis 11 | 1,696
ductal carcinoma in situ 11 | 1,745
Autosomal recessive predisposition 10 | 1,442
Cancer 10 | 2,499
colon cancer 10 | 1,478
interstitial cystitis 10 | 2,312
subependymal giant cell astrocytoma 10 | 2,287
ulcerative colitis 10 | 1,819
adrenocortical carcinoma 9 | 1,428
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,962
spina bifida 9 | 1,074
breast carcinoma 8 | 1,638
group 4 medulloblastoma 8 | 1,855
Rheumatoid arthritis 7 | 1,191
pituitary cancer 7 | 1,972
primary pancreatic ductal adenocarcinoma 7 | 1,109
Atopic dermatitis 6 | 952
esophageal adenocarcinoma 6 | 737
pancreatic carcinoma 6 | 562
pediatric high grade glioma 6 | 1,064
juvenile dermatomyositis 5 | 1,187
non primary Sjogren syndrome sicca 5 | 891
tuberculosis 5 | 2,010
Acquired metabolic disease 4 | 336
Alzheimer's disease 4 | 658
Anemia 4 | 365
Bipolar Disorder 4 | 666
Cataract 4 | 297
Cognitive delay 4 | 608
Epilepsy 4 | 792
Global developmental delay 4 | 608
Infantile onset 4 | 238
Intellectual disability 4 | 1,016
Mental and motor retardation 4 | 608
Multiple myeloma 4 | 1,332
Muscle hypotonia 4 | 571
Obesity 4 | 678
Prostatic Neoplasms 4 | 495
Seizures 4 | 596
Short stature 4 | 531
aldosterone-producing adenoma 4 | 665
astrocytoma 4 | 1,146
atypical teratoid/rhabdoid tumor 4 | 357
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 510
diabetes mellitus 4 | 1,728
nasopharyngeal carcinoma 4 | 1,058
nephrosclerosis 4 | 333
urothelial carcinoma 4 | 318
Duchenne muscular dystrophy 3 | 601
Dull intelligence 3 | 645
Endometriosis 3 | 540
Failure to gain weight 3 | 365
Lens Opacities 3 | 231
Liver Cirrhosis, Experimental 3 | 769
Low Vision 3 | 174
Low intelligence 3 | 645
Melanoma 3 | 711
Mental Retardation 3 | 645
Mental deficiency 3 | 645
Pediatric failure to thrive 3 | 365
Poor school performance 3 | 645
Small head 3 | 374
Type 2 diabetes mellitus 3 | 272
active Crohn's disease 3 | 922
acute myeloid leukemia 3 | 783
cutaneous lupus erythematosus 3 | 1,057
dermatomyositis 3 | 966
fibroadenoma 3 | 559
glioblastoma multiforme 3 | 142
head and neck cancer 3 | 271
medulloblastoma 3 | 720
sonic hedgehog group medulloblastoma 3 | 467
tuberculosis and treatment for 6 months 3 | 409

Tissue

Blood and immune system 68 | 16,909
Digestive Tract 68 | 17,369
Female tissues 68 | 17,400
Male tissues 68 | 17,142
Endocrine System 67 | 18,159
Liver and Pancreas 67 | 16,750
Nervous System 67 | 16,725
Skin and soft tissues 67 | 17,230
Respiratory system 66 | 16,393
Urinary Tract 66 | 16,678
Cardiovascular System 61 | 15,192

Target Family

Non-IDG 39 | 12,091
Enzyme 13 | 4,145
Epigenetic 3 | 242
Transporter 3 | 473
GPCR 2 | 408
Kinase 2 | 634
Nuclear Receptor 2 | 48
Transcription Factor 2 | 1,400
Ion Channel 1 | 344
TF/Epigenetic 1 | 38

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Suppressor of tumorigenicity 14 protein ST14 Tchem Non-IDG -2.50215 338.3 309
Transmembrane protein 160 TMEM160 Tdark Non-IDG 0.38 0.37 10
Beta/gamma crystallin domain-containing protein 1 CRYBG1 Tbio Non-IDG -1.13797 12.4 13
Lysosomal-associated transmembrane protein 4B LAPTM4B Tbio Non-IDG -1.90763 86.1 91
WAP four-disulfide core domain protein 1 WFDC1 Tbio Non-IDG -1.94592 87.9 127
Echinoderm microtubule-associated protein-like 2 EML2 Tdark Non-IDG -0.80456 4.27 93
Translation initiation factor eIF-2B subunit delta EIF2B4 Tbio Non-IDG -1.06082 11.3 145
ProSAAS PCSK1N Tbio Non-IDG -2.28833 188.0 73
Volume-regulated anion channel subunit LRRC8A LRRC8A Tbio Non-IDG -1.55179 39.4 129
Protein spinster homolog 2 SPNS2 Tbio Non-IDG -1.42853 26.4 88