Development Level

Tbio 27 | 11,445
Tdark 6 | 6,588
Tchem 5 | 1,598
Tclin 4 | 613

Collection

GPCR: IDG Consortium (Complete... 1 | 25
GPCR: IDG Consortium (Targets) 1 | 126
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

abnormal epididymis morphology 42 | 42
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

Carcinoma 27 | 11,493
psoriasis 22 | 6,694
glioblastoma 20 | 5,792
osteosarcoma 20 | 7,950
ovarian cancer 20 | 8,520
medulloblastoma, large-cell 17 | 6,241
ependymoma 16 | 4,679
intraductal papillary-mucinous neoplasm (IPMN) 16 | 3,291
atypical teratoid / rhabdoid tumor 14 | 5,112
Astrocytoma, Pilocytic 13 | 3,081
adult high grade glioma 13 | 3,801
group 3 medulloblastoma 11 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 11 | 2,955
lung cancer 11 | 4,740
lung carcinoma 11 | 2,843
Breast cancer 10 | 3,578
non-small cell lung cancer 10 | 2,890
oligodendroglioma 10 | 2,850
astrocytic glioma 9 | 2,597
interstitial cystitis 9 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,989
lung adenocarcinoma 9 | 2,716
pituitary cancer 9 | 1,972
primitive neuroectodermal tumor 9 | 3,035
malignant mesothelioma 8 | 3,232
ulcerative colitis 8 | 1,819
Cancer 7 | 2,499
Schizophrenia 7 | 1,160
subependymal giant cell astrocytoma 7 | 2,287
Pick disease 6 | 1,894
pancreatic cancer 6 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
tuberculosis 6 | 2,010
Epilepsy 5 | 792
Obesity 5 | 678
cystic fibrosis 5 | 1,696
Alzheimer's disease 4 | 658
Autosomal recessive predisposition 4 | 1,442
Bipolar Disorder 4 | 666
Kidney cancer 4 | 2,613
Rheumatoid arthritis 4 | 1,191
acute quadriplegic myopathy 4 | 1,158
adrenocortical carcinoma 4 | 1,428
group 4 medulloblastoma 4 | 1,855
invasive ductal carcinoma 4 | 2,951
pancreatic carcinoma 4 | 562
spina bifida 4 | 1,074
Autistic Disorder 3 | 364
Barrett's esophagus 3 | 182
Intellectual disability 3 | 1,016
Lung Neoplasms 3 | 232
Melanoma 3 | 711
Peripheral Neuropathy 3 | 134
Seizures 3 | 596
Stomach Neoplasms 3 | 300
active Crohn's disease 3 | 922
astrocytoma 3 | 1,146
esophageal adenocarcinoma 3 | 737
gastric cancer 3 | 459
juvenile dermatomyositis 3 | 1,187
medulloblastoma 3 | 720
nasopharyngeal carcinoma 3 | 1,058
pediatric high grade glioma 3 | 1,064
Amyotrophic lateral sclerosis 2 | 451
Attention deficit hyperactivity disorder 2 | 278
Bladder Neoplasm 2 | 112
Carcinoma, Hepatocellular 2 | 228
Cerebral atrophy 2 | 178
Colonic Neoplasms 2 | 142
Dementia 2 | 175
Diarrhea 2 | 253
Endometriosis 2 | 540
Failure to gain weight 2 | 365
Highly variable clinical phenotype 2 | 150
Highly variable phenotype and severity 2 | 150
Highly variable phenotype, even within families 2 | 150
Hypertension 2 | 396
Infantile onset 2 | 238
Liver cancer 2 | 604
Liver carcinoma 2 | 240
Mental Depression 2 | 333
Multiple Sclerosis 2 | 540
Neurodegenerative disease 2 | 414
Parkinson's disease 2 | 392
Pediatric failure to thrive 2 | 365
Phenotypic variability 2 | 150
Prostatic Neoplasms 2 | 495
Reperfusion Injury 2 | 86
Skin cancer 2 | 469
Urinary Bladder Neoplasms 2 | 114
active ulcerative colitis 2 | 764
atypical teratoid/rhabdoid tumor 2 | 357
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
breast carcinoma 2 | 1,638
colon cancer 2 | 1,478
mucosa-associated lymphoid tissue lymphoma 2 | 484
non diabetic and post-ischemic heart failure 2 | 200
primary pancreatic ductal adenocarcinoma 2 | 1,109
tuberculosis and treatment for 6 months 2 | 409
type II diabetes mellitus and post-ischemic heart failure 2 | 88

Tissue

Endocrine System 41 | 18,159
Female tissues 40 | 17,400
Nervous System 40 | 16,725
Digestive Tract 39 | 17,369
Male tissues 38 | 17,142
Skin and soft tissues 38 | 17,230
Liver and Pancreas 37 | 16,750
Blood and immune system 35 | 16,909
Respiratory system 35 | 16,393
Urinary Tract 35 | 16,678
Cardiovascular System 34 | 15,192

Target Family

Non-IDG 18 | 12,091
Enzyme 9 | 4,145
Ion Channel 4 | 344
GPCR 3 | 408
Kinase 3 | 634
Transcription Factor 2 | 1,400
Transporter 2 | 473
Epigenetic 1 | 242

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Caskin-1 CASKIN1 Tdark Non-IDG -0.63111 5.31 22
SLIT and NTRK-like protein 1 SLITRK1 Tbio Non-IDG -2.74906 555.5 206
Transmembrane protein 174 TMEM174 Tdark Non-IDG -0.39794 2.90 25
Transmembrane protein 106B TMEM106B Tbio Non-IDG -1.54017 36.2 87
Neuronal acetylcholine receptor subunit beta-2 CHRNB2 Tclin Ion Channel -1.62448 37.6 174
Dihydropyrimidine dehydrogenase [NADP(+)] DPYD Tclin Enzyme -2.62432 395.0 159
Sodium-dependent lysophosphatidylcholine symporter 1 MFSD2A Tbio Non-IDG -1.40175 26.3 73
Testis development-related protein TDRP Tbio Non-IDG -0.59437 4.93 39
Methylmalonic aciduria and homocystinuria type C protein MMACHC Tbio Non-IDG -1.83573 76.5 233
G protein-activated inward rectifier potassium channel 1 KCNJ3 Tchem Ion Channel -2.34432 217.2 267