Development Level

Tbio 20 | 11,445
Tchem 6 | 1,598
Tdark 3 | 6,588
Tclin 2 | 613

Collection

Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

abnormal embryo turning 31 | 31
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

Carcinoma 22 | 11,493
ovarian cancer 22 | 8,520
osteosarcoma 17 | 7,950
medulloblastoma, large-cell 14 | 6,241
psoriasis 13 | 6,694
atypical teratoid / rhabdoid tumor 11 | 5,112
ependymoma 11 | 4,679
group 3 medulloblastoma 11 | 4,104
lung cancer 11 | 4,740
glioblastoma 8 | 5,792
Autosomal recessive predisposition 6 | 1,442
Breast cancer 6 | 3,578
Cancer 6 | 2,499
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
Kidney cancer 5 | 2,613
adult high grade glioma 5 | 3,801
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
invasive ductal carcinoma 5 | 2,951
malignant mesothelioma 5 | 3,232
pancreatic cancer 5 | 2,398
Intellectual disability 4 | 1,016
Multiple myeloma 4 | 1,332
astrocytic glioma 4 | 2,597
breast carcinoma 4 | 1,638
cutaneous lupus erythematosus 4 | 1,057
non-small cell lung cancer 4 | 2,890
oligodendroglioma 4 | 2,850
pituitary cancer 4 | 1,972
primitive neuroectodermal tumor 4 | 3,035
Endometriosis 3 | 540
Pick disease 3 | 1,894
Schizophrenia 3 | 1,160
adrenocortical carcinoma 3 | 1,428
chronic rhinosinusitis 3 | 512
diabetes mellitus 3 | 1,728
ductal carcinoma in situ 3 | 1,745
group 4 medulloblastoma 3 | 1,855
lung adenocarcinoma 3 | 2,716
nasopharyngeal carcinoma 3 | 1,058
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
primary pancreatic ductal adenocarcinoma 3 | 1,109
tuberculosis 3 | 2,010
Alcoholic Intoxication, Chronic 2 | 289
Alzheimer's disease 2 | 658
Cataract 2 | 297
Cavernous hemangioma 2 | 11
Cerebrovascular disease 2 | 238
Colonic Neoplasms 2 | 142
Dermatologic disorders 2 | 93
Dull intelligence 2 | 645
Epilepsy 2 | 792
Failure to gain weight 2 | 365
Gastrointestinal Stromal Tumors 2 | 48
Low intelligence 2 | 645
Melanoma 2 | 711
Mental Retardation 2 | 645
Mental deficiency 2 | 645
Muscle hypotonia 2 | 571
Neurodegenerative disease 2 | 414
Orbital separation excessive 2 | 244
Pediatric failure to thrive 2 | 365
Poor school performance 2 | 645
Rheumatoid arthritis 2 | 1,191
Seizures 2 | 596
Skin Abnormalities 2 | 37
acute myeloid leukemia 2 | 783
dermatomyositis 2 | 966
esophageal adenocarcinoma 2 | 737
hereditary spastic paraplegia 2 | 318
interstitial cystitis 2 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
medulloblastoma 2 | 720
non primary Sjogren syndrome sicca 2 | 891
primary Sjogren syndrome 2 | 735
spina bifida 2 | 1,074
subependymal giant cell astrocytoma 2 | 2,287
Acute necrotizing encephalitis 1 | 2
Brain Diseases, Metabolic, Inborn 1 | 4
CHARGE syndrome 1 | 26
Congenital Abnormalities 1 | 11
Congenital Abnormality 1 | 11
Gait, Unsteady 1 | 29
Hemangioma, Cavernous, Central Nervous System 1 | 2
Hepatitis 1 | 67
Lipidoses 1 | 19
Lipoidosis 1 | 19
Malignant mesothelioma of pleura 1 | 7
Malignant tumor of lung 1 | 5
Measles 1 | 22
Meningeal Leukemia 1 | 7
Neurodegeneration Due To Cerebral Folate Transport Deficiency 1 | 1
Neurodegenerative syndrome due to cerebral folate transport deficiency 1 | 1
Osteosarcoma of bone 1 | 6
Polycystic Kidney, Autosomal Recessive 1 | 9
Psychomotor Disorders 1 | 7
Q fever 1 | 15
Rapidly progressive 1 | 27
Rapidly progressive disorder 1 | 27
Skin Neoplasms 1 | 69
biotin-responsive basal ganglia disease 1 | 8

Tissue

Blood and immune system 31 | 16,909
Digestive Tract 31 | 17,369
Female tissues 31 | 17,400
Nervous System 31 | 16,725
Skin and soft tissues 31 | 17,230
Cardiovascular System 30 | 15,192
Endocrine System 30 | 18,159
Liver and Pancreas 30 | 16,750
Male tissues 30 | 17,142
Respiratory system 30 | 16,393
Urinary Tract 30 | 16,678

Target Family

Non-IDG 14 | 12,091
Enzyme 10 | 4,145
Kinase 2 | 634
GPCR 1 | 408
Ion Channel 1 | 344
Nuclear Receptor 1 | 48
Transcription Factor 1 | 1,400
Transporter 1 | 473

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Progesterone-induced-blocking factor 1 PIBF1 Tbio Non-IDG -1.30666 21.1 209
Folate receptor alpha FOLR1 Tchem Non-IDG -2.33242 206.1 303
Phosphate carrier protein, mitochondrial SLC25A3 Tbio Transporter -2.85426 703.4 33
Smoothened homolog SMO Tclin GPCR -1.17466 14.5 415
Polycomb group RING finger protein 1 PCGF1 Tbio Non-IDG -0.99091 11.4 101
U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase METTL16 Tbio Enzyme -0.54935 4.80 160
Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial COQ6 Tbio Enzyme -1.26796 18.5 102
Replication factor C subunit 1 RFC1 Tbio Non-IDG -1.43459 26.5 198
Exocyst complex component 4 EXOC4 Tbio Non-IDG -1.61492 39.1 121
Complement component receptor 1-like protein CR1L Tdark Non-IDG -0.13712 1.58 29