Development Level

Tbio 154 | 11,445
Tchem 33 | 1,598
Tdark 26 | 6,588
Tclin 7 | 613

Collection

Kinase: IDG Consortium (Target... 3 | 125
Ion Channel: IDG Consortium (T... 1 | 99
Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

abnormal embryo size 220 | 220
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

Carcinoma 148 | 11,493
ovarian cancer 138 | 8,520
osteosarcoma 108 | 7,950
glioblastoma 80 | 5,792
medulloblastoma, large-cell 80 | 6,241
psoriasis 70 | 6,694
atypical teratoid / rhabdoid tumor 68 | 5,112
lung cancer 68 | 4,740
ependymoma 61 | 4,679
group 3 medulloblastoma 59 | 4,104
Breast cancer 55 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 47 | 3,291
malignant mesothelioma 46 | 3,232
Cancer 44 | 2,499
Kidney cancer 43 | 2,613
non-small cell lung cancer 42 | 2,890
primitive neuroectodermal tumor 41 | 3,035
astrocytic glioma 40 | 2,597
invasive ductal carcinoma 40 | 2,951
oligodendroglioma 40 | 2,850
adult high grade glioma 37 | 3,801
lung adenocarcinoma 37 | 2,716
intraductal papillary-mucinous carcinoma (IPMC) 36 | 2,989
Autosomal recessive predisposition 33 | 1,442
Pick disease 31 | 1,894
breast carcinoma 31 | 1,638
interstitial cystitis 31 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 31 | 2,955
pancreatic cancer 30 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 30 | 1,962
pituitary cancer 30 | 1,972
Astrocytoma, Pilocytic 29 | 3,081
ductal carcinoma in situ 28 | 1,745
adrenocortical carcinoma 27 | 1,428
group 4 medulloblastoma 26 | 1,855
lung carcinoma 25 | 2,843
tuberculosis 24 | 2,010
acute myeloid leukemia 23 | 783
subependymal giant cell astrocytoma 23 | 2,287
ulcerative colitis 23 | 1,819
astrocytoma 22 | 1,146
pediatric high grade glioma 22 | 1,064
Multiple myeloma 20 | 1,332
acute quadriplegic myopathy 20 | 1,158
colon cancer 20 | 1,478
dermatomyositis 20 | 966
spina bifida 20 | 1,074
Rheumatoid arthritis 19 | 1,191
Schizophrenia 19 | 1,160
non primary Sjogren syndrome sicca 19 | 891
primary pancreatic ductal adenocarcinoma 19 | 1,109
diabetes mellitus 18 | 1,728
nasopharyngeal carcinoma 16 | 1,058
juvenile dermatomyositis 15 | 1,187
Intellectual disability 14 | 1,016
Cognitive delay 13 | 608
Epilepsy 13 | 792
Global developmental delay 13 | 608
Mental and motor retardation 13 | 608
cystic fibrosis 12 | 1,696
Liver cancer 11 | 604
Obesity 11 | 678
Seizures 11 | 596
Waldenstrons macroglobulinemia 11 | 765
chronic rhinosinusitis 11 | 512
esophageal adenocarcinoma 11 | 737
gastric carcinoma 11 | 807
Alzheimer's disease 10 | 658
Neurodegenerative disease 10 | 414
Prostatic Neoplasms 10 | 495
Atopic dermatitis 9 | 952
Cleft Palate 9 | 271
Melanoma 9 | 711
Muscle hypotonia 9 | 571
Neuropathy 9 | 261
cutaneous lupus erythematosus 9 | 1,057
medulloblastoma 9 | 720
primary Sjogren syndrome 9 | 735
progressive supranuclear palsy 9 | 676
Amyotrophic lateral sclerosis 8 | 451
Cleft Lip 8 | 141
Endometriosis 8 | 540
Hepatomegaly 8 | 285
pancreatic carcinoma 8 | 562
tuberculosis and treatment for 6 months 8 | 409
Bipolar Disorder 7 | 666
Cataract 7 | 297
Down syndrome 7 | 499
Dull intelligence 7 | 645
Failure to gain weight 7 | 365
Fetal Growth Retardation 7 | 189
Infant, Small for Gestational Age 7 | 176
Intrauterine retardation 7 | 176
Low intelligence 7 | 645
Mental Retardation 7 | 645
Mental deficiency 7 | 645
Pediatric failure to thrive 7 | 365
Poor school performance 7 | 645
Short stature 7 | 531
Small head 7 | 374

Tissue

Endocrine System 218 | 18,159
Nervous System 216 | 16,725
Skin and soft tissues 216 | 17,230
Digestive Tract 215 | 17,369
Female tissues 215 | 17,400
Male tissues 215 | 17,142
Respiratory system 215 | 16,393
Blood and immune system 214 | 16,909
Urinary Tract 213 | 16,678
Liver and Pancreas 211 | 16,750
Cardiovascular System 206 | 15,192

Target Family

Non-IDG 108 | 12,091
Enzyme 59 | 4,145
Kinase 17 | 634
Transcription Factor 14 | 1,400
Epigenetic 8 | 242
Transporter 7 | 473
Ion Channel 5 | 344
Nuclear Receptor 1 | 48
TF/Epigenetic 1 | 38

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Suppressor of tumorigenicity 14 protein ST14 Tchem Non-IDG -2.50215 338.3 309
Iron-sulfur cluster assembly 1 homolog, mitochondrial ISCA1 Tbio Non-IDG -1.68100 45.7 44
Progesterone-induced-blocking factor 1 PIBF1 Tbio Non-IDG -1.30666 21.1 209
CTD small phosphatase-like protein 2 CTDSPL2 Tdark Enzyme -0.57403 3.70 102
Cytochrome c oxidase assembly factor 5 COA5 Tdark Enzyme -0.77512 6.90 3
Folate receptor alpha FOLR1 Tchem Non-IDG -2.33242 206.1 303
Polycomb group RING finger protein 1 PCGF1 Tbio Non-IDG -0.99091 11.4 101
THO complex subunit 6 homolog THOC6 Tbio Non-IDG -1.77416 57.9 131
Beta/gamma crystallin domain-containing protein 1 CRYBG1 Tbio Non-IDG -1.13797 12.4 13
Lysosomal-associated transmembrane protein 4B LAPTM4B Tbio Non-IDG -1.90763 86.1 91