Development Level

Tbio 8 | 11,445
Tdark 1 | 6,588

IMPC Phenotype

abnormal ear morphology 9 | 9
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

Carcinoma 7 | 11,493
atypical teratoid / rhabdoid tumor 6 | 5,112
ependymoma 6 | 4,679
glioblastoma 6 | 5,792
osteosarcoma 6 | 7,950
ovarian cancer 6 | 8,520
Pick disease 5 | 1,894
primitive neuroectodermal tumor 5 | 3,035
Astrocytoma, Pilocytic 4 | 3,081
astrocytic glioma 4 | 2,597
interstitial cystitis 4 | 2,312
oligodendroglioma 4 | 2,850
adult high grade glioma 3 | 3,801
ductal carcinoma in situ 3 | 1,745
group 3 medulloblastoma 3 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
lung cancer 3 | 4,740
pituitary cancer 3 | 1,972
psoriasis 3 | 6,694
Atopic dermatitis 2 | 952
Autosomal recessive predisposition 2 | 1,442
Cataract 2 | 297
Lens Opacities 2 | 231
Nonsyndromic deafness 2 | 142
Rheumatoid arthritis 2 | 1,191
Schizophrenia 2 | 1,160
Sensorineural Hearing Loss (disorder) 2 | 284
dermatomyositis 2 | 966
fibroadenoma 2 | 559
group 4 medulloblastoma 2 | 1,855
lung carcinoma 2 | 2,843
medulloblastoma, large-cell 2 | 6,241
spina bifida 2 | 1,074
Abnormal vision 1 | 52
Abnormality of cochlea 1 | 6
Abnormality of epiphysis morphology 1 | 39
Abortion, Spontaneous 1 | 109
Acquired immunodeficiency syndrome 1 | 197
Amblyopia 1 | 38
Arthralgia 1 | 90
Astigmatism 1 | 54
Atelosteogenesis 1 | 5
Cerebellar hypoplasia and atrophy 1 | 41
Chromosome 15q24 deletion syndrome 1 | 12
Clubfoot 1 | 39
Decreased joint mobility 1 | 53
Degenerative polyarthritis 1 | 115
Desbuquois dysplasia 1 | 13
Diastrophic dysplasia 1 | 21
Difficulties with night vision 1 | 87
Fibrochondrogenesis 1 | 7
Flat face 1 | 52
Gastrointestinal Stromal Tumors 1 | 48
Genu varum 1 | 29
Hemianopsia 1 | 15
High-grade hypermetropia 1 | 24
Hip Dislocation, Congenital 1 | 48
Hypertension 1 | 396
Hypotrophic malar bone 1 | 129
Irregular vertebral endplates 1 | 16
Joint hyperflexibility 1 | 78
Knee joint valgus deformity 1 | 56
Malar flattening 1 | 129
Micromelia 1 | 58
Motor delay 1 | 147
Myopia 1 | 176
Night Blindness 1 | 101
No development of motor milestones 1 | 147
Osteoarthritis 1 | 184
Osteochondritis dissecans 1 | 17
Pigmentary iris degeneration 1 | 20
Platyspondyly 1 | 56
Polycythemia 1 | 25
Prenatal onset 1 | 139
Primary ciliary dyskinesia 1 | 76
Profound sensorineural hearing impairment 1 | 4
Relative short stature 1 | 13
Retinal Detachment 1 | 51
Retinal blind spot 1 | 11
Scotoma 1 | 22
Short hands 1 | 50
Short stature, mild 1 | 13
Situs Inversus 1 | 65
Situs ambiguus 1 | 25
Spontaneous abortion 1 | 113
Substance-Related Disorders 1 | 115
Thrombophlebitis 1 | 19
Usher Syndrome, Type 1 1 | 7
Usher Syndrome, Type I 1 | 6
Usher syndrome 1 | 32
Vestibular hypofunction 1 | 7
Vitreoretinal degeneration 1 | 9
Waddling gait 1 | 34
atypical teratoid/rhabdoid tumor 1 | 357
cystic fibrosis 1 | 1,696
facioscapulohumeral dystrophy 1 | 288
hepatocellular carcinoma 1 | 547
pediatric high grade glioma 1 | 1,064
permanent atrial fibrillation 1 | 45

Tissue

Blood and immune system 9 | 16,909
Cardiovascular System 9 | 15,192
Digestive Tract 9 | 17,369
Endocrine System 9 | 18,159
Female tissues 9 | 17,400
Liver and Pancreas 9 | 16,750
Male tissues 9 | 17,142
Nervous System 9 | 16,725
Respiratory system 9 | 16,393
Skin and soft tissues 9 | 17,230
Urinary Tract 9 | 16,678

Target Family

Non-IDG 7 | 12,091
Enzyme 1 | 4,145
Transcription Factor 1 | 1,400

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Neuroplastin NPTN Tbio Non-IDG -2.31075 211.6 201
Nucleoside diphosphate kinase 7 NME7 Tbio Enzyme -0.83479 6.29 113
GA-binding protein alpha chain GABPA Tbio Transcription Factor -1.50283 31.7 289
Myelin protein zero-like protein 2 MPZL2 Tbio Non-IDG -1.08541 11.4 158
GATOR complex protein WDR59 WDR59 Tdark Non-IDG 0.01 0.25 35
Collagen alpha-2(IX) chain COL9A2 Tbio Non-IDG -1.59170 38.7 8
Calcium and integrin-binding family member 2 CIB2 Tbio Non-IDG -1.26911 16.6 148
ELMO domain-containing protein 1 ELMOD1 Tbio Non-IDG -0.16386 2.12 89
MARVEL domain-containing protein 2 MARVELD2 Tbio Non-IDG -1.73663 58.4 114