Development Level

Tbio 9 | 10,625
Tchem 3 | 1,890

IMPC Term

abnormal coping response 12 | 12
preweaning lethality, complete... 633 | 633
preweaning lethality, incomple... 260 | 260
abnormal behavior 226 | 226
decreased lean body mass 195 | 195
embryonic lethality prior to t... 187 | 187
decreased total body fat amoun... 186 | 186
decreased body weight 174 | 174
decreased bone mineral content 157 | 157
embryonic lethality prior to o... 148 | 148
abnormal bone structure 131 | 131
increased or absent threshold ... 128 | 128
decreased bone mineral density 126 | 126
decreased grip strength 123 | 123
decreased circulating glucose ... 121 | 121
increased circulating alkaline... 119 | 119
abnormal embryo size 112 | 112
enlarged heart 111 | 111
decreased body length 108 | 108
hyperactivity 108 | 108
increased lean body mass 107 | 107
abnormal retina morphology 100 | 100
increased mean corpuscular hem... 93 | 93
increased bone mineral content 92 | 92
increased mean corpuscular vol... 91 | 91
hypoactivity 89 | 89
decreased circulating choleste... 85 | 85
decreased circulating triglyce... 83 | 83
increased grip strength 83 | 83
short tibia 82 | 82
decreased circulating serum al... 79 | 79
decreased circulating HDL chol... 77 | 77
decreased circulating insulin ... 75 | 75
abnormal lens morphology 73 | 73
increased circulating sodium l... 71 | 71
increased fasted circulating g... 68 | 68
prenatal lethality prior to he... 64 | 64
abnormal sleep behavior 63 | 63
increased circulating HDL chol... 63 | 63
decreased lumbar vertebrae num... 62 | 62
increased sacral vertebrae num... 62 | 62
male infertility 62 | 62
abnormal retinal pigmentation 61 | 61
decreased rib number 59 | 59
increased total body fat amoun... 57 | 57
improved glucose tolerance 56 | 56
increased exploration in new e... 56 | 56
abnormal bone mineralization 55 | 55
abnormal coat/hair pigmentatio... 54 | 54
decreased leukocyte cell numbe... 54 | 54
decreased circulating alanine ... 53 | 53
decreased hemoglobin content 53 | 53
increased circulating choleste... 53 | 53
abnormal behavioral response t... 52 | 52
decreased prepulse inhibition 52 | 52
impaired glucose tolerance 52 | 52
increased bone mineral density 52 | 52
abnormal gait 51 | 51
abnormal heart morphology 51 | 51
decreased mean corpuscular vol... 50 | 50
decreased caudal vertebrae num... 49 | 49
decreased fasted circulating g... 49 | 49
decreased startle reflex 48 | 48
abnormal seminal vesicle morph... 47 | 47
thrombocytopenia 46 | 46
increased hemoglobin content 45 | 45
decreased heart weight 44 | 44
increased blood urea nitrogen ... 44 | 44
decreased erythrocyte cell num... 43 | 43
increased circulating chloride... 43 | 43
increased body weight 42 | 42
decreased circulating alkaline... 41 | 41
decreased circulating total pr... 41 | 41
decreased eosinophil cell numb... 41 | 41
increased rib number 41 | 41
decreased circulating free fat... 39 | 39
abnormal eye morphology 38 | 38
increased startle reflex 38 | 38
abnormal neural tube closure 37 | 37
decreased circulating LDL chol... 37 | 37
decreased neutrophil cell numb... 37 | 37
increased heart weight 37 | 37
increased leukocyte cell numbe... 37 | 37
small testis 37 | 37
abnormal spleen morphology 36 | 36
increased hematocrit 36 | 36
cardiovascular system phenotyp... 35 | 35
limb grasping 35 | 35
decreased mean corpuscular hem... 34 | 34
female infertility 34 | 34
tremors 34 | 34
decreased circulating calcium ... 33 | 33
abnormal cranium morphology 32 | 32
decreased circulating chloride... 32 | 32
decreased threshold for audito... 32 | 32
increased circulating calcium ... 32 | 32
abnormal epididymis morphology 31 | 31
decreased T cell number 31 | 31
decreased blood urea nitrogen ... 31 | 31
decreased circulating fructosa... 31 | 31
increased circulating potassiu... 31 | 31

Disease

osteosarcoma 9 | 7,933
psoriasis 9 | 6,685
ovarian cancer 7 | 8,484
Cancer 6 | 2,346
medulloblastoma, large-cell 6 | 6,234
oligodendroglioma 6 | 2,849
Breast cancer 5 | 3,094
atypical teratoid / rhabdoid tumor 5 | 4,369
ependymoma 5 | 2,514
glioblastoma 5 | 5,572
pediatric high grade glioma 5 | 2,712
astrocytic glioma 4 | 2,241
group 3 medulloblastoma 4 | 2,254
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,988
invasive ductal carcinoma 4 | 2,950
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,795
Atopic dermatitis 3 | 944
Pick disease 3 | 1,893
Rheumatoid Arthritis 3 | 1,160
active Crohn's disease 3 | 918
cystic fibrosis 3 | 1,665
ductal carcinoma in situ 3 | 1,745
head and neck cancer and chronic obstructive pulmonary disease 3 | 237
interstitial cystitis 3 | 2,299
juvenile dermatomyositis 3 | 1,189
lung adenocarcinoma 3 | 2,713
lung carcinoma 3 | 2,844
non-small cell lung cancer 3 | 2,798
pancreatic cancer 3 | 2,300
pilocytic astrocytoma 3 | 3,086
pituitary cancer 3 | 1,972
tuberculosis and treatment for 6 months 3 | 686
ulcerative colitis 3 | 2,087
Alzheimer's disease 2 | 644
Carcinoma 2 | 2,147
Craniosynostosis 2 | 47
Liver carcinoma 2 | 217
Multiple myeloma 2 | 1,327
Neurodegenerative disease 2 | 383
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 499
dermatomyositis 2 | 933
group 4 medulloblastoma 2 | 1,875
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,289
lung cancer 2 | 4,466
malignant mesothelioma 2 | 3,162
non primary Sjogren syndrome sicca 2 | 840
posterior fossa group A ependymoma 2 | 1,511
primitive neuroectodermal tumor 2 | 3,031
progressive supranuclear palsy 2 | 674
subependymal giant cell astrocytoma 2 | 2,287
tuberculosis 2 | 1,557
Adenoma 1 | 165
Anemia 1 | 252
Barrett's esophagus 1 | 183
Bohring syndrome 1 | 2
Brain disease 1 | 83
Cerebral amyloid angiopathy 1 | 9
Chronic obstructive pulmonary disease 1 | 146
Colorectal Neoplasms 1 | 217
Dementia 1 | 129
Dermatitis 1 | 107
Disease Progression 1 | 125
Encephalitis 1 | 54
Fragile X syndrome 1 | 31
Gaucher disease type 1 1 | 171
Hematologic cancer 1 | 9
Hepatitis C 1 | 90
Immune system cancer 1 | 38
Inflammatory bowel disease 1 | 142
Influenza 1 | 142
Juvenile Myelomonocytic Leukemia 1 | 21
Liver Cirrhosis 1 | 101
Lung disease 1 | 132
Mammary Neoplasms 1 | 410
Multiple Sclerosis 1 | 498
Muscle Weakness 1 | 92
Mycobacterium Infections, Nontuberculous 1 | 5
Necrosis 1 | 51
Neoplasm Metastasis 1 | 138
Nerve Degeneration 1 | 73
Paralysed 1 | 9
Polycythemia Vera 1 | 24
Prostate cancer 1 | 172
Renal Cell Carcinoma 1 | 199
Severe acute respiratory syndrome 1 | 26
Sideroblastic anemia 1 | 18
Spinal Cord Diseases 1 | 3
Toxic encephalopathy 1 | 131
Weight Gain 1 | 87
atypical teratoid/rhabdoid tumor 1 | 1,095
facioscapulohumeral dystrophy 1 | 286
head and neck cancer 1 | 270
hearing impairment 1 | 40
interstitial lung disease 1 | 291
limb girdle muscular dystrophy 2A 1 | 156
medulloblastoma 1 | 1,524
permanent atrial fibrillation 1 | 44
sarcoidosis 1 | 358
systemic lupus erythematosus 1 | 156

Tissue

Blood and immune system 12 | 17,995
Cardiovascular System 12 | 17,958
Digestive Tract 12 | 18,473
Endocrine System 12 | 18,512
Female tissues 12 | 18,647
Liver and Pancreas 12 | 18,136
Male tissues 12 | 17,969
Nervous System 12 | 18,561
Respiratory system 12 | 17,484
Skin and soft tissues 12 | 18,115
Urinary Tract 12 | 18,444

Target Family

Non-IDG 5 | 11,971
Enzyme 4 | 4,146
Epigenetic 1 | 242
Transcription Factor 1 | 1,400
Transporter 1 | 473

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
E3 ubiquitin-protein ligase Praja-1 PJA1 Tbio Enzyme -0.82785 7.04 108
Mediator of RNA polymerase II transcription subunit 18 MED18 Tbio Enzyme -0.79865 8.58 129
Cystine/glutamate transporter SLC7A11 Tchem Transporter -2.56381 385.0 219
Aconitate hydratase, mitochondrial ACO2 Tbio Enzyme -2.17104 145.2 256
Putative Polycomb group protein ASXL1 ASXL1 Tbio Epigenetic -2.12912 148.0 67
Hepatocyte growth factor-regulated tyrosine kinase substrate HGS Tbio Enzyme -2.83610 704.3 332
Enhancer of polycomb homolog 1 EPC1 Tbio Non-IDG -1.19738 16.9 59
ELMO domain-containing protein 1 ELMOD1 Tbio Non-IDG -0.17884 1.68 78
Secreted frizzled-related protein 2 SFRP2 Tbio Non-IDG -2.10726 143.5 164
Amyloid beta A4 protein APP Tchem Non-IDG -3.60404 4118.9 2173