Development Level

Tbio 53 | 11,445
Tdark 8 | 6,588
Tchem 2 | 1,598
Tclin 1 | 613

IMPC Phenotype

abnormal coat-hair pigmentatio... 64 | 64
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
abnormal bone mineralization 38 | 38
prolonged QT interval 38 | 38

Disease

ovarian cancer 41 | 8,520
osteosarcoma 37 | 7,950
Carcinoma 36 | 11,493
atypical teratoid / rhabdoid tumor 24 | 5,112
ependymoma 22 | 4,679
glioblastoma 22 | 5,792
medulloblastoma, large-cell 22 | 6,241
psoriasis 20 | 6,694
adult high grade glioma 17 | 3,801
group 3 medulloblastoma 17 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 17 | 3,291
Breast cancer 16 | 3,578
intraductal papillary-mucinous adenoma (IPMA) 16 | 2,955
lung cancer 16 | 4,740
primitive neuroectodermal tumor 15 | 3,035
oligodendroglioma 14 | 2,850
ulcerative colitis 14 | 1,819
Astrocytoma, Pilocytic 13 | 3,081
malignant mesothelioma 13 | 3,232
pancreatic ductal adenocarcinoma liver metastasis 13 | 1,962
astrocytic glioma 12 | 2,597
intraductal papillary-mucinous carcinoma (IPMC) 12 | 2,989
pancreatic cancer 12 | 2,398
Kidney cancer 11 | 2,613
group 4 medulloblastoma 10 | 1,855
interstitial cystitis 10 | 2,312
invasive ductal carcinoma 10 | 2,951
juvenile dermatomyositis 10 | 1,187
subependymal giant cell astrocytoma 10 | 2,287
Pick disease 9 | 1,894
lung carcinoma 9 | 2,843
non primary Sjogren syndrome sicca 9 | 891
non-small cell lung cancer 9 | 2,890
spina bifida 9 | 1,074
cystic fibrosis 8 | 1,696
Intellectual disability 7 | 1,016
Liver Cirrhosis, Experimental 7 | 769
astrocytoma 7 | 1,146
cutaneous lupus erythematosus 7 | 1,057
esophageal adenocarcinoma 7 | 737
lung adenocarcinoma 7 | 2,716
nasopharyngeal carcinoma 7 | 1,058
progressive supranuclear palsy 7 | 676
tuberculosis 7 | 2,010
Autosomal recessive predisposition 6 | 1,442
Cancer 6 | 2,499
Cognitive delay 6 | 608
Duchenne muscular dystrophy 6 | 601
Dull intelligence 6 | 645
Global developmental delay 6 | 608
Low intelligence 6 | 645
Mental Retardation 6 | 645
Mental and motor retardation 6 | 608
Mental deficiency 6 | 645
Poor school performance 6 | 645
autosomal dominant Emery-Dreifuss muscular dystrophy 6 | 510
breast carcinoma 6 | 1,638
ductal carcinoma in situ 6 | 1,745
Atopic dermatitis 5 | 952
Liver cancer 5 | 604
Rheumatoid arthritis 5 | 1,191
adrenocortical carcinoma 5 | 1,428
aldosterone-producing adenoma 5 | 665
colon cancer 5 | 1,478
pediatric high grade glioma 5 | 1,064
pituitary cancer 5 | 1,972
Becker muscular dystrophy 4 | 191
Hermansky-Pudlak syndrome 4 | 42
Mental Depression 4 | 333
Muscle hypotonia 4 | 571
Oculocutaneous albinism 4 | 29
dermatomyositis 4 | 966
periodontitis 4 | 293
primary Sjogren syndrome 4 | 735
primary pancreatic ductal adenocarcinoma 4 | 1,109
Acquired scoliosis 3 | 281
Bipolar Disorder 3 | 666
Curvature of spine 3 | 282
Depressive disorder 3 | 409
Down syndrome 3 | 499
Gaucher disease type 1 3 | 180
Melanoma 3 | 711
Multiple myeloma 3 | 1,332
Myocardial Ischemia 3 | 169
Nystagmus 3 | 317
Osteoporosis 3 | 363
Schizophrenia 3 | 1,160
Short stature 3 | 531
Thrombocytopenia 3 | 197
Waldenstrons macroglobulinemia 3 | 765
active Crohn's disease 3 | 922
acute myeloid leukemia 3 | 783
acute quadriplegic myopathy 3 | 1,158
diabetes mellitus 3 | 1,728
fibroadenoma 3 | 559
gastric cancer 3 | 459
gastric carcinoma 3 | 807
hepatocellular carcinoma 3 | 547
posterior fossa group B ependymoma 3 | 416
sonic hedgehog group medulloblastoma 3 | 467

Tissue

Endocrine System 64 | 18,159
Female tissues 64 | 17,400
Skin and soft tissues 63 | 17,230
Blood and immune system 62 | 16,909
Digestive Tract 62 | 17,369
Male tissues 62 | 17,142
Respiratory system 62 | 16,393
Urinary Tract 62 | 16,678
Liver and Pancreas 61 | 16,750
Nervous System 61 | 16,725
Cardiovascular System 58 | 15,192

Target Family

Non-IDG 41 | 12,091
Enzyme 16 | 4,145
Transcription Factor 3 | 1,400
Epigenetic 1 | 242
GPCR 1 | 408
Kinase 1 | 634
Transporter 1 | 473

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Relaxin-3 RLN3 Tbio Non-IDG -1.88808 92.6 93
Cysteine-rich hydrophobic domain-containing protein 2 CHIC2 Tbio Non-IDG -2.12710 132.1 97
Caskin-1 CASKIN1 Tdark Non-IDG -0.63111 5.31 22
Melanocyte-stimulating hormone receptor MC1R Tclin GPCR -2.90014 829.2 194
Zinc finger ZZ-type and EF-hand domain-containing protein 1 ZZEF1 Tdark Non-IDG 0.19 0.86 20
U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase METTL16 Tbio Enzyme -0.54935 4.80 160
E3 ubiquitin-protein ligase FANCL FANCL Tbio Enzyme -2.46302 286.2 146
Unconventional myosin-X MYO10 Tbio Non-IDG -1.49855 36.4 47
Lysosomal-trafficking regulator LYST Tbio Non-IDG -1.96473 92.5 15
U4/U6.U5 tri-snRNP-associated protein 2 USP39 Tbio Non-IDG -2.17711 150.5 112