Development Level

Tbio 90 | 10,625
Tchem 20 | 1,890
Tdark 16 | 7,003
Tclin 5 | 602

Collection

Ion Channel: IDG Consortium (Targets) 1 | 102
Kinase: IDG Consortium (Targets) 1 | 125

IMPC Phenotype

abnormal bone structure 131 | 131
preweaning lethality, complete... 633 | 633
preweaning lethality, incomple... 260 | 260
abnormal behavior 226 | 226
decreased lean body mass 195 | 195
embryonic lethality prior to t... 187 | 187
decreased total body fat amoun... 186 | 186
decreased body weight 174 | 174
decreased bone mineral content 157 | 157
embryonic lethality prior to o... 148 | 148
increased or absent threshold ... 128 | 128
decreased bone mineral density 126 | 126
decreased grip strength 123 | 123
decreased circulating glucose ... 121 | 121
increased circulating alkaline... 119 | 119
abnormal embryo size 112 | 112
enlarged heart 111 | 111
decreased body length 108 | 108
hyperactivity 108 | 108
increased lean body mass 107 | 107
abnormal retina morphology 100 | 100
increased mean corpuscular hem... 93 | 93
increased bone mineral content 92 | 92
increased mean corpuscular vol... 91 | 91
hypoactivity 89 | 89
decreased circulating choleste... 85 | 85
decreased circulating triglyce... 83 | 83
increased grip strength 83 | 83
short tibia 82 | 82
decreased circulating serum al... 79 | 79
decreased circulating HDL chol... 77 | 77
decreased circulating insulin ... 75 | 75
abnormal lens morphology 73 | 73
increased circulating sodium l... 71 | 71
increased fasted circulating g... 68 | 68
prenatal lethality prior to he... 64 | 64
abnormal sleep behavior 63 | 63
increased circulating HDL chol... 63 | 63
decreased lumbar vertebrae num... 62 | 62
increased sacral vertebrae num... 62 | 62
male infertility 62 | 62
abnormal retinal pigmentation 61 | 61
decreased rib number 59 | 59
increased total body fat amoun... 57 | 57
improved glucose tolerance 56 | 56
increased exploration in new e... 56 | 56
abnormal bone mineralization 55 | 55
abnormal coat-hair pigmentatio... 54 | 54
decreased leukocyte cell numbe... 54 | 54
decreased circulating alanine ... 53 | 53
decreased hemoglobin content 53 | 53
increased circulating choleste... 53 | 53
abnormal behavioral response t... 52 | 52
decreased prepulse inhibition 52 | 52
impaired glucose tolerance 52 | 52
increased bone mineral density 52 | 52
abnormal gait 51 | 51
abnormal heart morphology 51 | 51
decreased mean corpuscular vol... 50 | 50
decreased caudal vertebrae num... 49 | 49
decreased fasted circulating g... 49 | 49
decreased startle reflex 48 | 48
abnormal seminal vesicle morph... 47 | 47
thrombocytopenia 46 | 46
increased hemoglobin content 45 | 45
decreased heart weight 44 | 44
increased blood urea nitrogen ... 44 | 44
decreased erythrocyte cell num... 43 | 43
increased circulating chloride... 43 | 43
increased body weight 42 | 42
decreased circulating alkaline... 41 | 41
decreased circulating total pr... 41 | 41
decreased eosinophil cell numb... 41 | 41
increased rib number 41 | 41
decreased circulating free fat... 39 | 39
abnormal eye morphology 38 | 38
increased startle reflex 38 | 38
abnormal neural tube closure 37 | 37
decreased circulating LDL chol... 37 | 37
decreased neutrophil cell numb... 37 | 37
increased heart weight 37 | 37
increased leukocyte cell numbe... 37 | 37
small testis 37 | 37
abnormal spleen morphology 36 | 36
increased hematocrit 36 | 36
cardiovascular system phenotyp... 35 | 35
limb grasping 35 | 35
decreased mean corpuscular hem... 34 | 34
female infertility 34 | 34
tremors 34 | 34
decreased circulating calcium ... 33 | 33
abnormal cranium morphology 32 | 32
decreased circulating chloride... 32 | 32
decreased threshold for audito... 32 | 32
increased circulating calcium ... 32 | 32
abnormal epididymis morphology 31 | 31
decreased T cell number 31 | 31
decreased blood urea nitrogen ... 31 | 31
decreased circulating fructosa... 31 | 31
increased circulating potassiu... 31 | 31

Disease

ovarian cancer 69 | 8,491
osteosarcoma 65 | 7,933
glioblastoma 56 | 5,572
psoriasis 56 | 6,685
medulloblastoma, large-cell 54 | 6,234
atypical teratoid / rhabdoid tumor 42 | 4,369
lung cancer 36 | 4,473
pilocytic astrocytoma 36 | 3,086
primitive neuroectodermal tumor 33 | 3,031
intraductal papillary-mucinous neoplasm (IPMN) 31 | 3,289
subependymal giant cell astrocytoma 30 | 2,287
Breast cancer 29 | 3,098
pediatric high grade glioma 29 | 2,712
intraductal papillary-mucinous adenoma (IPMA) 27 | 2,956
oligodendroglioma 26 | 2,849
Pick disease 25 | 1,893
invasive ductal carcinoma 25 | 2,950
malignant mesothelioma 25 | 3,163
Cancer 24 | 2,346
intraductal papillary-mucinous carcinoma (IPMC) 24 | 2,988
adult high grade glioma 22 | 2,148
astrocytic glioma 22 | 2,241
pancreatic cancer 22 | 2,300
non-small cell lung cancer 20 | 2,798
Carcinoma 19 | 2,147
ductal carcinoma in situ 19 | 1,745
group 4 medulloblastoma 19 | 1,875
posterior fossa group A ependymoma 19 | 1,511
ependymoma 18 | 2,514
interstitial cystitis 18 | 2,299
medulloblastoma 17 | 1,524
pituitary cancer 17 | 1,972
astrocytoma 15 | 1,493
breast carcinoma 15 | 1,614
lung adenocarcinoma 15 | 2,714
lung carcinoma 15 | 2,844
cystic fibrosis 14 | 1,670
sonic hedgehog group medulloblastoma 14 | 1,482
spina bifida 14 | 1,064
posterior fossa group B ependymoma 13 | 1,530
ulcerative colitis 13 | 2,087
Obesity 12 | 616
adrenocortical carcinoma 12 | 1,427
colon cancer 12 | 1,475
cutaneous lupus erythematosus 12 | 1,056
group 3 medulloblastoma 12 | 2,254
primary pancreatic ductal adenocarcinoma 12 | 1,271
Alzheimer's disease 10 | 644
Rheumatoid Arthritis 10 | 1,170
atypical teratoid/rhabdoid tumor 10 | 1,095
juvenile dermatomyositis 10 | 1,189
pancreatic ductal adenocarcinoma liver metastasis 10 | 1,795
Intellectual disability 9 | 573
Parkinson's disease 9 | 364
tuberculosis 9 | 1,563
esophageal adenocarcinoma 8 | 737
tuberculosis and treatment for 6 months 8 | 686
Adenoma 7 | 165
Atopic dermatitis 7 | 944
Down syndrome 7 | 548
Hyperphosphatemia 7 | 32
nasopharyngeal carcinoma 7 | 1,056
non primary Sjogren syndrome sicca 7 | 840
Cushing's syndrome 6 | 47
Kidney cancer 6 | 121
Neurodegenerative disease 6 | 383
Polycystic Ovary Syndrome 6 | 334
acute myeloid leukemia 6 | 785
fibroadenoma 6 | 557
gastric carcinoma 6 | 832
progressive supranuclear palsy 6 | 674
Acromegaly 5 | 40
Duchenne muscular dystrophy 5 | 602
Epilepsy 5 | 346
Hyperthyroidism 5 | 50
Hypothyroidism 5 | 89
Kidney disease 5 | 397
McCune Albright syndrome 5 | 19
Multiple Endocrine Neoplasia Type 1 5 | 30
Multiple Sclerosis 5 | 498
Pituitary adenoma 5 | 35
autosomal dominant Emery-Dreifuss muscular dystrophy 5 | 499
diabetes mellitus 5 | 1,663
pancreatic carcinoma 5 | 567
primary Sjogren syndrome 5 | 788
Bipolar Disorder 4 | 266
Brachydactyly 4 | 52
Mammary Neoplasms 4 | 410
Renal Cell Carcinoma 4 | 199
Schizophrenia 4 | 503
Vascular disease 4 | 281
Waldenstrons macroglobulinemia 4 | 764
active Crohn's disease 4 | 918
acute quadriplegic myopathy 4 | 1,157
aldosterone-producing adenoma 4 | 664
chronic rhinosinusitis 4 | 512
dermatomyositis 4 | 966
hepatocellular carcinoma 4 | 550
hereditary spastic paraplegia 4 | 313
nephrosclerosis 4 | 329

Tissue

Digestive Tract 130 | 18,472
Nervous System 130 | 18,560
Cardiovascular System 129 | 17,957
Endocrine System 129 | 18,511
Female tissues 129 | 18,646
Liver and Pancreas 129 | 18,135
Urinary Tract 129 | 18,443
Male tissues 128 | 17,968
Blood and immune system 127 | 17,994
Respiratory system 127 | 17,483
Skin and soft tissues 126 | 18,114

Target Family

Non-IDG 62 | 11,969
Enzyme 36 | 4,146
Transcription Factor 11 | 1,400
Transporter 6 | 473
Epigenetic 4 | 242
Kinase 4 | 634
Ion Channel 3 | 341
GPCR 2 | 408
TF/Epigenetic 2 | 38
Nuclear Receptor 1 | 48

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
E3 ubiquitin-protein ligase UHRF2 UHRF2 Tbio Epigenetic -1.53825 36.6 184
AT-rich interactive domain-containing protein 3A ARID3A Tbio Transcription Factor -2.07434 111.0 153
Transcription regulator protein BACH2 BACH2 Tbio Transcription Factor -1.84608 77.3 159
IQ motif and SEC7 domain-containing protein 3 IQSEC3 Tdark Non-IDG -0.15983 1.60 50
DNA-binding protein SATB1 SATB1 Tbio Transcription Factor -2.24334 197.9 293
Erlin-2 ERLIN2 Tbio Non-IDG -1.24133 18.7 148
Guanine nucleotide-binding protein G(s) subunit alpha isoforms short GNAS Tbio Non-IDG -2.60782 1308.3 400
Neurabin-2 PPP1R9B Tbio Non-IDG 0.00000 0
E3 ubiquitin-protein ligase MARCH9 MARCH9 Tbio Enzyme -0.95067 9.08 93
Tubulin polymerization-promoting protein TPPP Tbio Non-IDG -1.92136 86.5 157