Development Level

Tbio 22 | 11,445
Tchem 7 | 1,598
Tdark 6 | 6,588
Tclin 3 | 613

IMPC Phenotype

abnormal bone mineralization 38 | 38
preweaning lethality, complete... 979 | 979
preweaning lethality, incomple... 499 | 499
abnormal behavior 298 | 298
embryonic lethality prior to t... 278 | 278
embryonic lethality prior to o... 239 | 239
abnormal embryo size 220 | 220
enlarged heart 210 | 210
decreased vertical activity 208 | 208
decreased total body fat amoun... 207 | 207
abnormal bone structure 187 | 187
increased lean body mass 172 | 172
abnormal heart morphology 162 | 162
decreased body weight 161 | 161
decreased bone mineral content 151 | 151
hyperactivity 148 | 148
decreased lean body mass 135 | 135
increased total body fat amoun... 134 | 134
hypoactivity 132 | 132
decreased bone mineral density 126 | 126
decreased circulating glucose ... 126 | 126
male infertility 123 | 123
increased circulating alkaline... 122 | 122
decreased grip strength 116 | 116
abnormal seminal vesicle morph... 114 | 114
increased startle reflex 112 | 112
increased bone mineral content 108 | 108
embryonic growth retardation 106 | 106
decreased body length 101 | 101
increased or absent threshold ... 101 | 101
short tibia 97 | 97
increased mean corpuscular hem... 96 | 96
decreased circulating choleste... 93 | 93
cataract 92 | 92
increased mean corpuscular vol... 92 | 92
prenatal lethality prior to he... 87 | 87
decreased lymphocyte cell numb... 83 | 83
decreased circulating serum al... 82 | 82
decreased prepulse inhibition 82 | 82
abnormal lens morphology 81 | 81
increased circulating HDL chol... 80 | 80
decreased circulating triglyce... 79 | 79
decreased mean corpuscular vol... 79 | 79
improved glucose tolerance 79 | 79
decreased circulating insulin ... 76 | 76
increased fasted circulating g... 76 | 76
decreased startle reflex 75 | 75
impaired glucose tolerance 75 | 75
small superior vagus ganglion 74 | 74
decreased leukocyte cell numbe... 73 | 73
increased bone mineral density 72 | 72
abnormal retina morphology 71 | 71
increased circulating sodium l... 71 | 71
abnormal sleep behavior 70 | 70
abnormal gait 69 | 69
abnormal eye morphology 68 | 68
decreased circulating HDL chol... 68 | 68
decreased hemoglobin content 68 | 68
abnormal behavioral response t... 66 | 66
increased circulating choleste... 66 | 66
abnormal kidney morphology 65 | 65
decreased fasted circulating g... 65 | 65
abnormal coat-hair pigmentatio... 64 | 64
increased monocyte cell number 63 | 63
decreased erythrocyte cell num... 62 | 62
increased heart weight 62 | 62
female infertility 60 | 60
edema 59 | 59
small testis 58 | 58
thrombocytopenia 56 | 56
abnormal spleen morphology 55 | 55
decreased caudal vertebrae num... 53 | 53
hydrometra 53 | 53
decreased blood urea nitrogen ... 51 | 51
abnormal skin morphology 50 | 50
decreased mean corpuscular hem... 50 | 50
decreased circulating total pr... 49 | 49
increased blood urea nitrogen ... 48 | 48
decreased circulating alanine ... 47 | 47
increased leukocyte cell numbe... 47 | 47
abnormal neural tube closure 46 | 46
decreased circulating alkaline... 46 | 46
decreased hematocrit 46 | 46
increased hematocrit 46 | 46
increased neutrophil cell numb... 46 | 46
increased hemoglobin content 45 | 45
increased mean platelet volume 45 | 45
abnormal testis morphology 43 | 43
abnormal epididymis morphology 42 | 42
decreased neutrophil cell numb... 42 | 42
increased circulating triglyce... 42 | 42
decreased red blood cell distr... 41 | 41
enlarged spleen 41 | 41
increased circulating chloride... 41 | 41
increased grip strength 41 | 41
limb grasping 41 | 41
decreased circulating creatini... 39 | 39
increased erythrocyte cell num... 39 | 39
tremors 39 | 39
prolonged QT interval 38 | 38

Disease

Carcinoma 33 | 11,493
ovarian cancer 26 | 8,520
osteosarcoma 22 | 7,950
medulloblastoma, large-cell 18 | 6,241
psoriasis 16 | 6,694
glioblastoma 15 | 5,792
lung cancer 15 | 4,740
atypical teratoid / rhabdoid tumor 13 | 5,112
Breast cancer 12 | 3,578
ependymoma 12 | 4,679
malignant mesothelioma 11 | 3,232
subependymal giant cell astrocytoma 10 | 2,287
Cancer 9 | 2,499
group 3 medulloblastoma 9 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,955
primitive neuroectodermal tumor 9 | 3,035
breast carcinoma 8 | 1,638
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,291
invasive ductal carcinoma 8 | 2,951
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,989
pediatric high grade glioma 7 | 1,064
tuberculosis 7 | 2,010
Astrocytoma, Pilocytic 6 | 3,081
astrocytoma 6 | 1,146
lung carcinoma 6 | 2,843
non-small cell lung cancer 6 | 2,890
pancreatic cancer 6 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
pituitary cancer 6 | 1,972
spina bifida 6 | 1,074
Bipolar Disorder 5 | 666
Obesity 5 | 678
Schizophrenia 5 | 1,160
adrenocortical carcinoma 5 | 1,428
adult high grade glioma 5 | 3,801
colon cancer 5 | 1,478
cystic fibrosis 5 | 1,696
diabetes mellitus 5 | 1,728
ductal carcinoma in situ 5 | 1,745
group 4 medulloblastoma 5 | 1,855
oligodendroglioma 5 | 2,850
Autosomal recessive predisposition 4 | 1,442
Rheumatoid arthritis 4 | 1,191
astrocytic glioma 4 | 2,597
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 510
gastric carcinoma 4 | 807
interstitial cystitis 4 | 2,312
lung adenocarcinoma 4 | 2,716
medulloblastoma 4 | 720
Breast Neoplasms 3 | 445
Cognitive delay 3 | 608
Colorectal Neoplasms 3 | 243
Dull intelligence 3 | 645
Epilepsy 3 | 792
Global developmental delay 3 | 608
Intellectual disability 3 | 1,016
Kidney cancer 3 | 2,613
Low intelligence 3 | 645
Mammary Neoplasms 3 | 425
Melanoma 3 | 711
Mental Retardation 3 | 645
Mental and motor retardation 3 | 608
Mental deficiency 3 | 645
Muscle hypotonia 3 | 571
Pick disease 3 | 1,894
Poor school performance 3 | 645
acute quadriplegic myopathy 3 | 1,158
dermatomyositis 3 | 966
juvenile dermatomyositis 3 | 1,187
nasopharyngeal carcinoma 3 | 1,058
non primary Sjogren syndrome sicca 3 | 891
primary pancreatic ductal adenocarcinoma 3 | 1,109
Adenoma 2 | 167
Alzheimer's disease 2 | 658
Carcinoma, Hepatocellular 2 | 228
Chronic Lymphocytic Leukemia 2 | 262
Endometrial cancer 2 | 311
Endometriosis 2 | 540
Hepatomegaly 2 | 285
Infantile onset 2 | 238
Inflammatory bowel disease 2 | 151
Kidney disease 2 | 430
Liver Cirrhosis 2 | 181
Liver carcinoma 2 | 240
Long philtrum 2 | 137
Neurodevelopmental Disorders 2 | 70
Prostate cancer 2 | 175
Seizures 2 | 596
Vascular disease 2 | 319
Vomiting 2 | 116
aldosterone-producing adenoma 2 | 665
chronic lymphosyte leukemia 2 | 204
chronic rhinosinusitis 2 | 512
esophageal adenocarcinoma 2 | 737
fibroadenoma 2 | 559
hepatocellular carcinoma 2 | 547
limb girdle muscular dystrophy 2A 2 | 213
posterior fossa group B ependymoma 2 | 416
primary Sjogren syndrome 2 | 735
ulcerative colitis 2 | 1,819

Tissue

Blood and immune system 37 | 16,909
Digestive Tract 37 | 17,369
Endocrine System 37 | 18,159
Female tissues 37 | 17,400
Liver and Pancreas 37 | 16,750
Male tissues 37 | 17,142
Nervous System 37 | 16,725
Respiratory system 37 | 16,393
Skin and soft tissues 37 | 17,230
Urinary Tract 37 | 16,678
Cardiovascular System 34 | 15,192

Target Family

Non-IDG 16 | 12,091
Enzyme 12 | 4,145
Transcription Factor 4 | 1,400
Ion Channel 2 | 344
Kinase 2 | 634
Nuclear Receptor 1 | 48
Transporter 1 | 473

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
X-box-binding protein 1 XBP1 Tchem Transcription Factor -2.90444 780.2 514
F-box only protein 11 FBXO11 Tbio Non-IDG -1.53905 34.1 258
6-phosphogluconate dehydrogenase, decarboxylating PGD Tchem Enzyme -2.56683 355.7 211
Unconventional myosin-VIIa MYO7A Tbio Non-IDG -2.14713 133.5 129
Putative sodium-coupled neutral amino acid transporter 10 SLC38A10 Tdark Transporter -0.27712 1.71 25
Cytochrome b561 CYB561 Tbio Non-IDG -1.41422 21.1 62
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 PLCG2 Tchem Enzyme -2.41628 245.1 733
ETS domain-containing protein Elk-4 ELK4 Tbio Transcription Factor -1.07328 11.4 100
E3 ubiquitin-protein ligase RNF169 RNF169 Tbio Enzyme -0.16291 2.08 60
Xylulose kinase XYLB Tbio Kinase -1.97293 93.1 74