Development Level

Tbio 30 | 10,625
Tdark 12 | 7,003
Tchem 7 | 1,890
Tclin 3 | 602

Collection

Eligible Kinase Proteins 1 | 134

IMPC Term

abnormal behavioral response t... 52 | 52
preweaning lethality, complete... 633 | 633
preweaning lethality, incomple... 260 | 260
abnormal behavior 226 | 226
decreased lean body mass 195 | 195
embryonic lethality prior to t... 187 | 187
decreased total body fat amoun... 186 | 186
decreased body weight 174 | 174
decreased bone mineral content 157 | 157
embryonic lethality prior to o... 148 | 148
abnormal bone structure 131 | 131
increased or absent threshold ... 128 | 128
decreased bone mineral density 126 | 126
decreased grip strength 123 | 123
decreased circulating glucose ... 121 | 121
increased circulating alkaline... 119 | 119
abnormal embryo size 112 | 112
enlarged heart 111 | 111
decreased body length 108 | 108
hyperactivity 108 | 108
increased lean body mass 107 | 107
abnormal retina morphology 100 | 100
increased mean corpuscular hem... 93 | 93
increased bone mineral content 92 | 92
increased mean corpuscular vol... 91 | 91
hypoactivity 89 | 89
decreased circulating choleste... 85 | 85
decreased circulating triglyce... 83 | 83
increased grip strength 83 | 83
short tibia 82 | 82
decreased circulating serum al... 79 | 79
decreased circulating HDL chol... 77 | 77
decreased circulating insulin ... 75 | 75
abnormal lens morphology 73 | 73
increased circulating sodium l... 71 | 71
increased fasted circulating g... 68 | 68
prenatal lethality prior to he... 64 | 64
abnormal sleep behavior 63 | 63
increased circulating HDL chol... 63 | 63
decreased lumbar vertebrae num... 62 | 62
increased sacral vertebrae num... 62 | 62
male infertility 62 | 62
abnormal retinal pigmentation 61 | 61
decreased rib number 59 | 59
increased total body fat amoun... 57 | 57
improved glucose tolerance 56 | 56
increased exploration in new e... 56 | 56
abnormal bone mineralization 55 | 55
abnormal coat/hair pigmentatio... 54 | 54
decreased leukocyte cell numbe... 54 | 54
decreased circulating alanine ... 53 | 53
decreased hemoglobin content 53 | 53
increased circulating choleste... 53 | 53
decreased prepulse inhibition 52 | 52
impaired glucose tolerance 52 | 52
increased bone mineral density 52 | 52
abnormal gait 51 | 51
abnormal heart morphology 51 | 51
decreased mean corpuscular vol... 50 | 50
decreased caudal vertebrae num... 49 | 49
decreased fasted circulating g... 49 | 49
decreased startle reflex 48 | 48
abnormal seminal vesicle morph... 47 | 47
thrombocytopenia 46 | 46
increased hemoglobin content 45 | 45
decreased heart weight 44 | 44
increased blood urea nitrogen ... 44 | 44
decreased erythrocyte cell num... 43 | 43
increased circulating chloride... 43 | 43
increased body weight 42 | 42
decreased circulating alkaline... 41 | 41
decreased circulating total pr... 41 | 41
decreased eosinophil cell numb... 41 | 41
increased rib number 41 | 41
decreased circulating free fat... 39 | 39
abnormal eye morphology 38 | 38
increased startle reflex 38 | 38
abnormal neural tube closure 37 | 37
decreased circulating LDL chol... 37 | 37
decreased neutrophil cell numb... 37 | 37
increased heart weight 37 | 37
increased leukocyte cell numbe... 37 | 37
small testis 37 | 37
abnormal spleen morphology 36 | 36
increased hematocrit 36 | 36
cardiovascular system phenotyp... 35 | 35
limb grasping 35 | 35
decreased mean corpuscular hem... 34 | 34
female infertility 34 | 34
tremors 34 | 34
decreased circulating calcium ... 33 | 33
abnormal cranium morphology 32 | 32
decreased circulating chloride... 32 | 32
decreased threshold for audito... 32 | 32
increased circulating calcium ... 32 | 32
abnormal epididymis morphology 31 | 31
decreased T cell number 31 | 31
decreased blood urea nitrogen ... 31 | 31
decreased circulating fructosa... 31 | 31
increased circulating potassiu... 31 | 31

Disease

osteosarcoma 24 | 7,933
ovarian cancer 24 | 8,484
psoriasis 23 | 6,685
medulloblastoma, large-cell 18 | 6,234
atypical teratoid / rhabdoid tumor 13 | 4,369
lung cancer 13 | 4,466
Breast cancer 11 | 3,094
non-small cell lung cancer 11 | 2,798
glioblastoma 10 | 5,572
group 3 medulloblastoma 10 | 2,254
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,988
malignant mesothelioma 10 | 3,162
pituitary cancer 10 | 1,972
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,956
cystic fibrosis 8 | 1,665
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,289
lung carcinoma 8 | 2,844
oligodendroglioma 8 | 2,849
primitive neuroectodermal tumor 8 | 3,031
interstitial cystitis 7 | 2,299
invasive ductal carcinoma 7 | 2,950
lung adenocarcinoma 7 | 2,713
pilocytic astrocytoma 7 | 3,086
astrocytic glioma 6 | 2,241
ductal carcinoma in situ 6 | 1,745
pediatric high grade glioma 6 | 2,712
Carcinoma 5 | 2,147
adrenocortical carcinoma 5 | 1,427
astrocytoma 5 | 1,493
chronic rhinosinusitis 5 | 512
ependymoma 5 | 2,514
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,795
sonic hedgehog group medulloblastoma 5 | 1,482
subependymal giant cell astrocytoma 5 | 2,287
ulcerative colitis 5 | 2,087
Atopic dermatitis 4 | 944
Cancer 4 | 2,346
Pick disease 4 | 1,893
adult high grade glioma 4 | 2,148
atypical teratoid/rhabdoid tumor 4 | 1,095
group 4 medulloblastoma 4 | 1,875
pancreatic cancer 4 | 2,300
posterior fossa group A ependymoma 4 | 1,511
spina bifida 4 | 1,064
Alzheimer's disease 3 | 644
Cocaine-Related Disorders 3 | 88
Endometriosis 3 | 535
Obesity 3 | 616
Parkinson's disease 3 | 364
Schizophrenia 3 | 501
breast carcinoma 3 | 1,614
colon cancer 3 | 1,475
cutaneous lupus erythematosus 3 | 1,056
esophageal adenocarcinoma 3 | 737
juvenile dermatomyositis 3 | 1,189
nasopharyngeal carcinoma 3 | 1,056
posterior fossa group B ependymoma 3 | 1,530
primary pancreatic ductal adenocarcinoma 3 | 1,271
Alcohol dependence 2 | 107
Amnestic disorder 2 | 37
Asthma 2 | 349
Attention deficit hyperactivity disorder 2 | 156
Autistic Disorder 2 | 320
Celiac disease 2 | 112
Common cold 2 | 63
Down syndrome 2 | 548
Duchenne muscular dystrophy 2 | 602
Eosinophilia 2 | 65
Eosinophilic esophagitis 2 | 31
Epilepsy 2 | 346
Intellectual disability 2 | 573
Major Depressive Disorder 2 | 106
Microcephaly 2 | 149
Migraine 2 | 79
Multiple myeloma 2 | 1,327
Neurodegenerative disease 2 | 383
Neuropathy 2 | 210
Personality disorder 2 | 25
Platelet mean volume finding 2 | 31
Rheumatoid Arthritis 2 | 1,160
Seizures 2 | 95
Stomach Neoplasms 2 | 282
Substance abuse 2 | 55
acute quadriplegic myopathy 2 | 1,157
dermatomyositis 2 | 933
diabetes mellitus 2 | 1,663
gastric carcinoma 2 | 832
medulloblastoma 2 | 1,524
nephrosclerosis 2 | 329
non diabetic and post-ischemic heart failure 2 | 200
primary Sjogren syndrome 2 | 789
tuberculosis and treatment for 3 months 2 | 327
uncontrolled asthma 2 | 67
Acne vulgaris 1 | 16
Esophagitis 1 | 26
Pain 1 | 70
Prevention of Radiation-Induced Nausea and Vomiting 1 | 7
Psychoses, Substance-Induced 1 | 17
Refractive error 1 | 43
Subacute thyroiditis 1 | 5

Tissue

Cardiovascular System 52 | 17,958
Endocrine System 52 | 18,512
Nervous System 52 | 18,561
Digestive Tract 51 | 18,473
Female tissues 51 | 18,647
Urinary Tract 51 | 18,444
Blood and immune system 50 | 17,995
Liver and Pancreas 50 | 18,136
Male tissues 50 | 17,969
Skin and soft tissues 50 | 18,115
Respiratory system 49 | 17,484

Target Family

Non-IDG 28 | 11,971
Enzyme 13 | 4,146
GPCR 3 | 406
Kinase 3 | 634
Transcription Factor 3 | 1,400
Epigenetic 1 | 242
Transporter 1 | 473

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Prolyl endopeptidase PREP Tchem Enzyme -2.51026 335.2 140
Synaptonemal complex protein 3 SYCP3 Tbio Non-IDG -2.15623 144.9 251
Hemojuvelin HFE2 Tbio Non-IDG -2.13078 140.4 244
Transmembrane protein 151B TMEM151B Tdark Non-IDG 0.00000 55
Beta-citrylglutamate synthase B RIMKLB Tdark Enzyme -0.36798 2.63 45
Iron-sulfur cluster assembly 1 homolog, mitochondrial ISCA1 Tbio Non-IDG -1.60430 39.0 31
N-chimaerin CHN1 Tbio Non-IDG -2.38189 241.1 189
Carbohydrate deacetylase YDJC Tdark Enzyme -0.30206 2.02 48
DnaJ homolog subfamily C member 28 DNAJC28 Tbio Non-IDG -1.08705 10.6 81
Estradiol 17-beta-dehydrogenase 1 HSD17B1 Tchem Enzyme -2.31436 205.7 174