Development Level

Tbio 282 | 11,651
Tdark 91 | 6,593
Tchem 28 | 1,388
Tclin 8 | 612

Collection

Kinase: IDG Consortium (Target... 3 | 125
RFA-RM-18-021 3 | 328
Kinase: IDG Consortium (Comple... 2 | 37

IMPC Phenotype

preweaning lethality, complete... 39 | 979
preweaning lethality, incomple... 15 | 499
abnormal behavior 11 | 298
embryonic lethality prior to t... 10 | 278
decreased body weight 9 | 161
increased total body fat amoun... 9 | 134
abnormal embryo size 8 | 220
decreased total body fat amoun... 7 | 207
decreased bone mineral density 6 | 126
decreased lean body mass 6 | 135
decreased leukocyte cell numbe... 6 | 73
hyperactivity 6 | 148
increased lean body mass 6 | 172
abnormal bone structure 5 | 187
decreased body length 5 | 101
decreased circulating triglyce... 5 | 79
decreased erythrocyte cell num... 5 | 62
decreased vertical activity 5 | 208
embryonic lethality prior to o... 5 | 239
increased bone mineral density 5 | 72
abnormal sleep behavior 4 | 70
decreased bone mineral content 4 | 151
decreased circulating HDL chol... 4 | 68
decreased circulating insulin ... 4 | 76
decreased hematocrit 4 | 46
embryonic growth retardation 4 | 106
enlarged heart 4 | 210
increased bone mineral content 4 | 108
increased mean corpuscular hem... 4 | 96
increased or absent threshold ... 4 | 101
short tibia 4 | 97
abnormal cornea morphology 3 | 31
abnormal eye morphology 3 | 68
abnormal heart morphology 3 | 162
abnormal skin morphology 3 | 50
abnormal startle reflex 3 | 15
corneal opacity 3 | 32
decreased caudal vertebrae num... 3 | 53
decreased circulating choleste... 3 | 93
decreased circulating sodium l... 3 | 22
decreased circulating total pr... 3 | 49
decreased fasted circulating g... 3 | 65
decreased hemoglobin content 3 | 68
decreased lymphocyte cell numb... 3 | 83
decreased neutrophil cell numb... 3 | 42
decreased prepulse inhibition 3 | 82
increased mean corpuscular vol... 3 | 92
increased startle reflex 3 | 112
male infertility 3 | 123
prenatal lethality prior to he... 3 | 87
prolonged QT interval 3 | 38
tremors 3 | 39
abnormal bone mineralization 2 | 38
abnormal coat- hair morphology 2 | 19
abnormal coat-hair pigmentatio... 2 | 64
abnormal cranium morphology 2 | 36
abnormal epididymis morphology 2 | 42
abnormal femur morphology 2 | 14
abnormal locomotor activation 2 | 16
abnormal pelvic girdle bone mo... 2 | 12
abnormal retina morphology 2 | 71
abnormal skin coloration 2 | 25
abnormal vocalization 2 | 21
anophthalmia 2 | 33
cardiovascular system phenotyp... 2 | 36
decreased circulating LDL chol... 2 | 38
decreased circulating alanine ... 2 | 47
decreased circulating chloride... 2 | 30
decreased circulating fructosa... 2 | 30
decreased circulating glucose ... 2 | 126
decreased circulating serum al... 2 | 82
enlarged epididymis 2 | 31
hypoactivity 2 | 132
impaired glucose tolerance 2 | 75
increased blood uric acid leve... 2 | 5
increased circulating HDL chol... 2 | 80
increased circulating alkaline... 2 | 122
increased circulating chloride... 2 | 41
increased circulating choleste... 2 | 66
increased circulating free fat... 2 | 20
increased erythrocyte cell num... 2 | 39
increased heart weight 2 | 62
increased thermal nociceptive ... 2 | 9
microphthalmia 2 | 26
pallor 2 | 34
persistence of hyaloid vascula... 2 | 33
prenatal lethality 2 | 28
prolonged ST segment 2 | 36
thrombocytosis 2 | 27
trunk curl 2 | 16
vertebral fusion 2 | 23
abnormal body wall morphology 1 | 9
abnormal spleen morphology 1 | 55
decreased T cell number 1 | 15
decreased eosinophil cell numb... 1 | 24
decreased red blood cell distr... 1 | 41
enlarged spleen 1 | 41
impaired pupillary reflex 1 | 26
increased body length 1 | 32
increased circulating phosphat... 1 | 26

Disease

tuberculosis and treatment for 6 months 409 | 409
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Blood and immune system 408 | 16,909
Cardiovascular System 408 | 15,192
Digestive Tract 408 | 17,369
Endocrine System 408 | 18,159
Female tissues 408 | 17,400
Liver and Pancreas 408 | 16,750
Male tissues 408 | 17,142
Respiratory system 408 | 16,393
Skin and soft tissues 408 | 17,230
Urinary Tract 408 | 16,678
Nervous System 407 | 16,725

Target Family

Non-IDG 238 | 12,091
Enzyme 94 | 4,145
Transcription Factor 41 | 1,400
Kinase 18 | 634
Epigenetic 12 | 242
Transporter 4 | 473
GPCR 1 | 408
Ion Channel 1 | 344

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
ETS-related transcription factor Elf-2 ELF2 Tbio Transcription Factor -2.04794 106.4 92
Protein arginine methyltransferase NDUFAF7, mitochondrial NDUFAF7 Tbio Enzyme -0.45102 2.70 64
Tripeptidyl-peptidase 2 TPP2 Tbio Enzyme -1.97332 108.2 72
Heterogeneous nuclear ribonucleoprotein A0 HNRNPA0 Tbio Non-IDG -0.86935 6.45 110
AMME syndrome candidate gene 1 protein AMMECR1 Tbio Non-IDG -0.63077 4.76 84
Mediator of RNA polymerase II transcription subunit 18 MED18 Tbio Enzyme -1.00423 10.4 161
E3 ubiquitin-protein ligase MYLIP MYLIP Tbio Enzyme -2.05580 115.6 135
AN1-type zinc finger protein 4 ZFAND4 Tdark Non-IDG -0.40937 2.62 28
Myotubularin-related protein 10 MTMR10 Tdark Non-IDG 0.10 0.58 25
BAG family molecular chaperone regulator 5 BAG5 Tbio Non-IDG -1.25287 18.4 376