Development Level

Tbio 61 | 10,625
Tdark 21 | 7,003
Tchem 14 | 1,890
Tclin 8 | 602

IMPC Phenotype

decreased bone mineral content 3 | 157
decreased bone mineral density 3 | 126
abnormal cranium morphology 2 | 32
decreased body length 2 | 108
decreased circulating HDL chol... 2 | 77
decreased circulating glucose ... 2 | 121
decreased lean body mass 2 | 195
decreased mean corpuscular hem... 2 | 19
decreased mean corpuscular vol... 2 | 50
increased circulating sodium l... 2 | 71
increased fasted circulating g... 2 | 68
abnormal behavior 1 | 226
abnormal bone mineralization 1 | 55
abnormal bone structure 1 | 131
abnormal coat-hair pigmentatio... 1 | 54
abnormal cornea morphology 1 | 24
abnormal iris morphology 1 | 12
abnormal lens morphology 1 | 73
abnormal response to tactile s... 1 | 16
abnormal retinal blood vessel ... 1 | 18
abnormal sleep behavior 1 | 63
abnormal startle reflex 1 | 14
abnormal tooth morphology 1 | 24
absent pinna reflex 1 | 21
cardiovascular system phenotyp... 1 | 35
cataract 1 | 26
corneal opacity 1 | 25
decreased CD4-positive, alpha ... 1 | 19
decreased CD8-positive, alpha-... 1 | 26
decreased Ly6C low monocyte nu... 1 | 23
decreased T cell number 1 | 31
decreased body weight 1 | 174
decreased cardiac muscle contr... 1 | 5
decreased circulating LDL chol... 1 | 37
decreased circulating alkaline... 1 | 41
decreased circulating choleste... 1 | 85
decreased circulating insulin ... 1 | 75
decreased circulating potassiu... 1 | 17
decreased circulating total pr... 1 | 41
decreased heart weight 1 | 44
decreased mean corpuscular hem... 1 | 34
decreased total body fat amoun... 1 | 186
embryonic lethality prior to o... 1 | 148
fused cornea and lens 1 | 4
hyperactivity 1 | 108
impaired pupillary reflex 1 | 14
increased Ly6C high monocyte n... 1 | 12
increased circulating alkaline... 1 | 119
increased circulating fructosa... 1 | 11
increased erythrocyte cell num... 1 | 26
increased mean corpuscular vol... 1 | 91
increased total body fat amoun... 1 | 57
mydriasis 1 | 9
narrow eye opening 1 | 15
persistence of hyaloid vascula... 1 | 22
prenatal lethality prior to he... 1 | 64
preweaning lethality, complete... 1 | 633
preweaning lethality, incomple... 1 | 260
short tail 1 | 4
thrombocytopenia 1 | 46

Disease

substance-related disorder 104 | 104
ovarian cancer 8,491 | 8,491
osteosarcoma 7,933 | 7,933
psoriasis 6,685 | 6,685
medulloblastoma, large-cell 6,234 | 6,234
glioblastoma 5,572 | 5,572
lung cancer 4,473 | 4,473
atypical teratoid / rhabdoid tumor 4,369 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 3,289 | 3,289
malignant mesothelioma 3,163 | 3,163
Breast cancer 3,098 | 3,098
pilocytic astrocytoma 3,086 | 3,086
primitive neuroectodermal tumor 3,031 | 3,031
intraductal papillary-mucinous carcinoma (IPMC) 2,988 | 2,988
intraductal papillary-mucinous adenoma (IPMA) 2,956 | 2,956
invasive ductal carcinoma 2,950 | 2,950
oligodendroglioma 2,849 | 2,849
lung carcinoma 2,844 | 2,844
non-small cell lung cancer 2,798 | 2,798
lung adenocarcinoma 2,714 | 2,714
pediatric high grade glioma 2,712 | 2,712
ependymoma 2,514 | 2,514
Cancer 2,346 | 2,346
pancreatic cancer 2,300 | 2,300
interstitial cystitis 2,299 | 2,299
subependymal giant cell astrocytoma 2,287 | 2,287
group 3 medulloblastoma 2,254 | 2,254
astrocytic glioma 2,241 | 2,241
adult high grade glioma 2,148 | 2,148
Carcinoma 2,147 | 2,147
ulcerative colitis 2,087 | 2,087
pituitary cancer 1,972 | 1,972
Pick disease 1,893 | 1,893
group 4 medulloblastoma 1,875 | 1,875
pancreatic ductal adenocarcinoma liver metastasis 1,795 | 1,795
ductal carcinoma in situ 1,745 | 1,745
cystic fibrosis 1,670 | 1,670
diabetes mellitus 1,663 | 1,663
breast carcinoma 1,614 | 1,614
tuberculosis 1,563 | 1,563
posterior fossa group B ependymoma 1,530 | 1,530
medulloblastoma 1,524 | 1,524
posterior fossa group A ependymoma 1,511 | 1,511
astrocytoma 1,493 | 1,493
sonic hedgehog group medulloblastoma 1,482 | 1,482
colon cancer 1,475 | 1,475
adrenocortical carcinoma 1,427 | 1,427
Multiple myeloma 1,327 | 1,327
primary pancreatic ductal adenocarcinoma 1,271 | 1,271
juvenile dermatomyositis 1,189 | 1,189
Rheumatoid Arthritis 1,170 | 1,170
acute quadriplegic myopathy 1,157 | 1,157
atypical teratoid/rhabdoid tumor 1,095 | 1,095
spina bifida 1,064 | 1,064
cutaneous lupus erythematosus 1,056 | 1,056
nasopharyngeal carcinoma 1,056 | 1,056
dermatomyositis 966 | 966
Atopic dermatitis 944 | 944
active Crohn's disease 918 | 918
non primary Sjogren syndrome sicca 840 | 840
gastric carcinoma 832 | 832
primary Sjogren syndrome 788 | 788
acute myeloid leukemia 785 | 785
Waldenstrons macroglobulinemia 764 | 764
esophageal adenocarcinoma 737 | 737
tuberculosis and treatment for 6 months 686 | 686
progressive supranuclear palsy 674 | 674
aldosterone-producing adenoma 664 | 664
Alzheimer's disease 644 | 644
Obesity 616 | 616
Duchenne muscular dystrophy 602 | 602
Intellectual disability 573 | 573
pancreatic carcinoma 567 | 567
fibroadenoma 557 | 557
hepatocellular carcinoma 550 | 550
Down syndrome 548 | 548
Endometriosis 535 | 535
chronic rhinosinusitis 512 | 512
Schizophrenia 503 | 503
autosomal dominant Emery-Dreifuss muscular dystrophy 499 | 499
Multiple Sclerosis 498 | 498
mucosa-associated lymphoid tissue lymphoma 480 | 480
active ulcerative colitis 477 | 477
Prostatic Neoplasms 471 | 471
IGA Glomerulonephritis 454 | 454
gastric cancer 436 | 436
Amyotrophic Lateral Sclerosis 432 | 432
non-small cell lung carcinoma 413 | 413
Mammary Neoplasms 410 | 410
inflammatory breast cancer 404 | 404
Kidney disease 397 | 397
Neurodegenerative disease 383 | 383
sarcoidosis 368 | 368
Parkinson's disease 364 | 364
Asthma 349 | 349
glioblastoma multiforme 347 | 347
Epilepsy 346 | 346
Polycystic Ovary Syndrome 334 | 334
nephrosclerosis 329 | 329
tuberculosis and treatment for 3 months 327 | 327
Autistic Disorder 320 | 320

Tissue

Cardiovascular System 99 | 17,957
Digestive Tract 99 | 18,472
Endocrine System 99 | 18,511
Female tissues 99 | 18,646
Liver and Pancreas 99 | 18,135
Male tissues 99 | 17,968
Nervous System 99 | 18,560
Skin and soft tissues 99 | 18,114
Urinary Tract 99 | 18,443
Respiratory system 98 | 17,483
Blood and immune system 97 | 17,994

Target Family

Non-IDG 52 | 11,969
Enzyme 29 | 4,146
Transcription Factor 9 | 1,400
Ion Channel 8 | 341
GPCR 3 | 408
Epigenetic 1 | 242
Kinase 1 | 634
Transporter 1 | 473

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 MAGI1 Tbio Enzyme -1.04868 9.00 130
Neuronal acetylcholine receptor subunit beta-4 CHRNB4 Tclin Ion Channel -1.54794 32.2 109
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 AGAP1 Tbio Enzyme -0.82492 9.19 84
Collagen alpha-1(VIII) chain COL8A1 Tbio Non-IDG -1.25305 16.3 98
Cytochrome P450 1A1 CYP1A1 Tchem Non-IDG -3.53853 3553.5 340
Autism susceptibility gene 2 protein AUTS2 Tbio Non-IDG -1.57099 36.9 74
Disabled homolog 2 DAB2 Tbio Non-IDG -2.24622 174.6 226
Peroxisomal trans-2-enoyl-CoA reductase PECR Tbio Enzyme -1.60889 41.8 84
Uncharacterized protein C7orf66 C7orf66 Tdark Non-IDG 0.00000 0
H(+)/Cl(-) exchange transporter 4 CLCN4 Tbio Ion Channel -1.50168 31.6 116