Development Level

Tbio 220 | 10,625
Tchem 58 | 1,890
Tdark 56 | 7,003
Tclin 24 | 602

Collection

Eligible Kinase Proteins 4 | 134
Eligible Ion Channel Proteins 2 | 117
Eligible non-olfactory GPCR Proteins 2 | 143

IMPC Term

preweaning lethality, complete... 10 | 633
decreased grip strength 6 | 123
decreased T cell number 5 | 31
decreased mean corpuscular hem... 5 | 34
decreased mean corpuscular vol... 5 | 50
decreased total body fat amoun... 5 | 186
preweaning lethality, incomple... 5 | 260
abnormal retina morphology 4 | 100
decreased circulating alanine ... 4 | 53
decreased lean body mass 4 | 195
increased circulating HDL chol... 4 | 63
increased circulating alkaline... 4 | 119
abnormal behavior 3 | 226
abnormal bone structure 3 | 131
decreased circulating HDL chol... 3 | 77
decreased circulating choleste... 3 | 85
decreased circulating triglyce... 3 | 83
decreased fasted circulating g... 3 | 49
decreased leukocyte cell numbe... 3 | 54
hypoactivity 3 | 89
increased circulating calcium ... 3 | 32
increased circulating choleste... 3 | 53
increased heart weight 3 | 37
increased or absent threshold ... 3 | 128
abnormal coat/hair pigmentatio... 2 | 54
abnormal cranium morphology 2 | 32
abnormal lens morphology 2 | 73
abnormal sleep behavior 2 | 63
cataract 2 | 26
decreased CD4-positive, alpha ... 2 | 19
decreased CD8-positive, alpha-... 2 | 26
decreased NK T cell number 2 | 28
decreased alpha-beta T cell nu... 2 | 12
decreased body length 2 | 108
decreased bone mineral content 2 | 157
decreased caudal vertebrae num... 2 | 49
decreased circulating alkaline... 2 | 41
decreased circulating glucose ... 2 | 121
decreased circulating insulin ... 2 | 75
decreased startle reflex 2 | 48
embryonic lethality prior to t... 2 | 187
female infertility 2 | 34
hyperactivity 2 | 108
increased body length 2 | 20
increased circulating sodium l... 2 | 71
increased eosinophil cell numb... 2 | 9
increased erythrocyte cell num... 2 | 26
increased fasted circulating g... 2 | 68
increased leukocyte cell numbe... 2 | 37
limb grasping 2 | 35
male infertility 2 | 62
thrombocytopenia 2 | 46
abnormal coping response 1 | 12
abnormal embryo size 1 | 112
abnormal retinal pigmentation 1 | 61
abnormal rib morphology 1 | 28
abnormal snout morphology 1 | 18
abnormal spleen morphology 1 | 36
abnormal thoracic vertebrae mo... 1 | 16
abnormal tooth morphology 1 | 24
abnormal vibrissa morphology 1 | 17
decreased CD4-positive, CD25-p... 1 | 24
decreased blood urea nitrogen ... 1 | 31
decreased bone mineral density 1 | 126
decreased circulating calcium ... 1 | 33
decreased circulating creatini... 1 | 31
decreased circulating iron lev... 1 | 25
decreased circulating magnesiu... 1 | 11
decreased circulating phosphat... 1 | 15
decreased circulating serum al... 1 | 79
decreased eosinophil cell numb... 1 | 41
decreased gamma-delta T cell n... 1 | 18
decreased heart weight 1 | 44
decreased hematocrit 1 | 25
decreased hemoglobin content 1 | 53
decreased lumbar vertebrae num... 1 | 62
decreased monocyte cell number 1 | 28
decreased red blood cell distr... 1 | 11
decreased rib number 1 | 59
decreased vertical activity 1 | 22
dilated heart left ventricle 1 | 10
embryonic lethality prior to o... 1 | 148
enlarged lymph nodes 1 | 27
impaired glucose tolerance 1 | 52
increased CD4-positive, CD25-p... 1 | 18
increased blood urea nitrogen ... 1 | 44
increased body weight 1 | 42
increased circulating total pr... 1 | 20
increased circulating triglyce... 1 | 24
increased grip strength 1 | 83
increased lean body mass 1 | 107
increased mean corpuscular vol... 1 | 91
increased prepulse inhibition 1 | 21
increased respiratory quotient 1 | 12
increased rib number 1 | 41
increased sacral vertebrae num... 1 | 62
increased startle reflex 1 | 38
prolonged PR interval 1 | 4
tremors 1 | 34
vertebral fusion 1 | 23

Disease

sarcoidosis 358 | 358
ovarian cancer 8,484 | 8,484
osteosarcoma 7,933 | 7,933
psoriasis 6,685 | 6,685
medulloblastoma, large-cell 6,234 | 6,234
glioblastoma 5,572 | 5,572
lung cancer 4,466 | 4,466
atypical teratoid / rhabdoid tumor 4,369 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 3,289 | 3,289
malignant mesothelioma 3,162 | 3,162
Breast cancer 3,094 | 3,094
pilocytic astrocytoma 3,086 | 3,086
primitive neuroectodermal tumor 3,031 | 3,031
intraductal papillary-mucinous carcinoma (IPMC) 2,988 | 2,988
intraductal papillary-mucinous adenoma (IPMA) 2,956 | 2,956
invasive ductal carcinoma 2,950 | 2,950
oligodendroglioma 2,849 | 2,849
lung carcinoma 2,844 | 2,844
non-small cell lung cancer 2,798 | 2,798
lung adenocarcinoma 2,713 | 2,713
pediatric high grade glioma 2,712 | 2,712
ependymoma 2,514 | 2,514
Cancer 2,346 | 2,346
pancreatic cancer 2,300 | 2,300
interstitial cystitis 2,299 | 2,299
subependymal giant cell astrocytoma 2,287 | 2,287
group 3 medulloblastoma 2,254 | 2,254
astrocytic glioma 2,241 | 2,241
adult high grade glioma 2,148 | 2,148
Carcinoma 2,147 | 2,147
ulcerative colitis 2,087 | 2,087
pituitary cancer 1,972 | 1,972
Pick disease 1,893 | 1,893
group 4 medulloblastoma 1,875 | 1,875
pancreatic ductal adenocarcinoma liver metastasis 1,795 | 1,795
ductal carcinoma in situ 1,745 | 1,745
cystic fibrosis 1,665 | 1,665
diabetes mellitus 1,663 | 1,663
breast carcinoma 1,614 | 1,614
tuberculosis 1,557 | 1,557
posterior fossa group B ependymoma 1,530 | 1,530
medulloblastoma 1,524 | 1,524
posterior fossa group A ependymoma 1,511 | 1,511
astrocytoma 1,493 | 1,493
sonic hedgehog group medulloblastoma 1,482 | 1,482
colon cancer 1,475 | 1,475
adrenocortical carcinoma 1,427 | 1,427
Multiple myeloma 1,327 | 1,327
primary pancreatic ductal adenocarcinoma 1,271 | 1,271
juvenile dermatomyositis 1,189 | 1,189
Rheumatoid Arthritis 1,160 | 1,160
acute quadriplegic myopathy 1,157 | 1,157
atypical teratoid/rhabdoid tumor 1,095 | 1,095
spina bifida 1,064 | 1,064
cutaneous lupus erythematosus 1,056 | 1,056
nasopharyngeal carcinoma 1,056 | 1,056
Atopic dermatitis 944 | 944
dermatomyositis 933 | 933
active Crohn's disease 918 | 918
non primary Sjogren syndrome sicca 840 | 840
gastric carcinoma 832 | 832
primary Sjogren syndrome 789 | 789
acute myeloid leukemia 780 | 780
Waldenstrons macroglobulinemia 765 | 765
esophageal adenocarcinoma 737 | 737
tuberculosis and treatment for 6 months 686 | 686
progressive supranuclear palsy 674 | 674
aldosterone-producing adenoma 664 | 664
Alzheimer's disease 644 | 644
Obesity 616 | 616
Duchenne muscular dystrophy 602 | 602
Intellectual disability 573 | 573
pancreatic carcinoma 567 | 567
fibroadenoma 557 | 557
Down syndrome 548 | 548
Endometriosis 535 | 535
hepatocellular carcinoma 532 | 532
chronic rhinosinusitis 512 | 512
Schizophrenia 501 | 501
autosomal dominant Emery-Dreifuss muscular dystrophy 499 | 499
Multiple Sclerosis 498 | 498
mucosa-associated lymphoid tissue lymphoma 480 | 480
active ulcerative colitis 477 | 477
Prostatic Neoplasms 471 | 471
IGA Glomerulonephritis 454 | 454
Amyotrophic Lateral Sclerosis 431 | 431
gastric cancer 430 | 430
non-small cell lung carcinoma 413 | 413
Mammary Neoplasms 410 | 410
inflammatory breast cancer 404 | 404
Kidney disease 396 | 396
Neurodegenerative disease 383 | 383
Parkinson's disease 364 | 364
Asthma 349 | 349
glioblastoma multiforme 347 | 347
Epilepsy 346 | 346
Polycystic Ovary Syndrome 332 | 332
nephrosclerosis 329 | 329
tuberculosis and treatment for 3 months 327 | 327
Autistic Disorder 320 | 320

Tissue

Digestive Tract 353 | 18,473
Female tissues 353 | 18,647
Blood and immune system 352 | 17,995
Endocrine System 352 | 18,512
Nervous System 352 | 18,561
Urinary Tract 352 | 18,444
Liver and Pancreas 351 | 18,136
Respiratory system 351 | 17,484
Male tissues 350 | 17,969
Cardiovascular System 349 | 17,958
Skin and soft tissues 347 | 18,115

Target Family

Non-IDG 215 | 11,971
Enzyme 73 | 4,146
Transcription Factor 29 | 1,400
Kinase 17 | 634
GPCR 8 | 406
Transporter 7 | 473
Ion Channel 5 | 341
Epigenetic 3 | 242
Nuclear Receptor 1 | 48

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Zinc finger and BTB domain-containing protein 1 ZBTB1 Tbio Transcription Factor -0.57513 5.01 57
Interleukin-1 beta IL1B Tclin Non-IDG -4.34333 22444.2 1345
Interleukin-15 IL15 Tbio Non-IDG -3.01964 1248.2 612
Killer cell lectin-like receptor subfamily B member 1 KLRB1 Tbio Non-IDG -2.39953 313.9 488
m7GpppN-mRNA hydrolase DCP2 Tbio Enzyme -1.89749 80.7 139
Macrophage metalloelastase MMP12 Tchem Enzyme 0.00000 382
Glycophorin-A GYPA Tbio Non-IDG -3.07931 1160.8 704
Coiled-coil domain-containing protein 88B CCDC88B Tdark Non-IDG -0.65642 5.36 36
Glycine amidinotransferase, mitochondrial GATM Tbio Enzyme -2.31313 210.4 193
Single-strand selective monofunctional uracil DNA glycosylase SMUG1 Tbio Enzyme -4.25142 18890.7 165