Development Level

Tbio 163 | 10,625
Tchem 49 | 1,890
Tdark 35 | 7,003
Tclin 22 | 602

Collection

Eligible Kinase Proteins 2 | 134

IMPC Term

decreased body weight 4 | 174
decreased total body fat amoun... 4 | 186
preweaning lethality, complete... 4 | 633
preweaning lethality, incomple... 4 | 260
short tibia 4 | 82
abnormal behavior 3 | 226
decreased circulating insulin ... 3 | 75
increased circulating sodium l... 3 | 71
thrombocytopenia 3 | 46
trunk curl 3 | 15
abnormal coat/hair pigmentatio... 2 | 54
abnormal vibrissa morphology 2 | 17
decreased body length 2 | 108
decreased bone mineral content 2 | 157
decreased circulating triglyce... 2 | 83
decreased lean body mass 2 | 195
decreased mean corpuscular hem... 2 | 34
decreased prepulse inhibition 2 | 52
decreased startle reflex 2 | 48
hyperactivity 2 | 108
increased bone mineral content 2 | 92
increased circulating chloride... 2 | 43
increased circulating serum al... 2 | 25
increased circulating total pr... 2 | 20
increased mean corpuscular hem... 2 | 93
increased mean corpuscular vol... 2 | 91
tremors 2 | 34
abnormal bone structure 1 | 131
abnormal coping response 1 | 12
abnormal cornea morphology 1 | 24
abnormal ear morphology 1 | 5
abnormal eye size 1 | 11
abnormal gait 1 | 51
abnormal heart morphology 1 | 51
abnormal lens morphology 1 | 73
abnormal locomotor activation 1 | 26
abnormal response to tactile s... 1 | 16
abnormal spleen morphology 1 | 36
abnormal startle reflex 1 | 14
abnormal testis morphology 1 | 30
absent startle reflex 1 | 15
cataract 1 | 26
circling 1 | 1
corneal opacity 1 | 25
corneal vascularization 1 | 5
decreased B cell number 1 | 30
decreased NK cell number 1 | 16
decreased blood urea nitrogen ... 1 | 31
decreased bone mineral density 1 | 126
decreased cervical vertebrae n... 1 | 12
decreased circulating HDL chol... 1 | 77
decreased circulating alanine ... 1 | 53
decreased circulating amylase ... 1 | 24
decreased circulating bilirubi... 1 | 14
decreased circulating choleste... 1 | 85
decreased circulating free fat... 1 | 39
decreased circulating glucose ... 1 | 121
decreased circulating glycerol... 1 | 19
decreased circulating potassiu... 1 | 17
decreased effector memory CD8-... 1 | 24
decreased eosinophil cell numb... 1 | 41
decreased erythrocyte cell num... 1 | 43
decreased grip strength 1 | 123
decreased heart rate 1 | 10
decreased heart weight 1 | 44
decreased hemoglobin content 1 | 53
decreased leukocyte cell numbe... 1 | 54
decreased lumbar vertebrae num... 1 | 62
decreased mean corpuscular vol... 1 | 50
decreased mean platelet volume 1 | 12
decreased rib number 1 | 59
decreased spleen weight 1 | 13
decreased threshold for audito... 1 | 32
enlarged heart 1 | 111
female infertility 1 | 34
head bobbing 1 | 3
hypoactivity 1 | 89
impaired pupillary reflex 1 | 14
impaired righting response 1 | 19
improved glucose tolerance 1 | 56
increased T cell number 1 | 15
increased blood urea nitrogen ... 1 | 44
increased bone mineral density 1 | 52
increased circulating alkaline... 1 | 119
increased circulating calcium ... 1 | 32
increased circulating potassiu... 1 | 31
increased fasted circulating g... 1 | 68
increased hemoglobin content 1 | 45
increased lean body mass 1 | 107
increased neutrophil cell numb... 1 | 15
increased or absent threshold ... 1 | 128
increased sacral vertebrae num... 1 | 62
increased spleen weight 1 | 3
narrow eye opening 1 | 15
persistence of hyaloid vascula... 1 | 22
prolonged RR interval 1 | 2
small testis 1 | 37
stereotypic behavior 1 | 3
straub tail 1 | 26
vertebral fusion 1 | 23

Disease

periodontitis 269 | 269
ovarian cancer 8,484 | 8,484
osteosarcoma 7,933 | 7,933
psoriasis 6,685 | 6,685
medulloblastoma, large-cell 6,234 | 6,234
glioblastoma 5,572 | 5,572
lung cancer 4,466 | 4,466
atypical teratoid / rhabdoid tumor 4,369 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 3,289 | 3,289
malignant mesothelioma 3,162 | 3,162
Breast cancer 3,094 | 3,094
pilocytic astrocytoma 3,086 | 3,086
primitive neuroectodermal tumor 3,031 | 3,031
intraductal papillary-mucinous carcinoma (IPMC) 2,988 | 2,988
intraductal papillary-mucinous adenoma (IPMA) 2,956 | 2,956
invasive ductal carcinoma 2,950 | 2,950
oligodendroglioma 2,849 | 2,849
lung carcinoma 2,844 | 2,844
non-small cell lung cancer 2,798 | 2,798
lung adenocarcinoma 2,713 | 2,713
pediatric high grade glioma 2,712 | 2,712
ependymoma 2,514 | 2,514
Cancer 2,346 | 2,346
pancreatic cancer 2,300 | 2,300
interstitial cystitis 2,299 | 2,299
subependymal giant cell astrocytoma 2,287 | 2,287
group 3 medulloblastoma 2,254 | 2,254
astrocytic glioma 2,241 | 2,241
adult high grade glioma 2,148 | 2,148
Carcinoma 2,147 | 2,147
ulcerative colitis 2,087 | 2,087
pituitary cancer 1,972 | 1,972
Pick disease 1,893 | 1,893
group 4 medulloblastoma 1,875 | 1,875
pancreatic ductal adenocarcinoma liver metastasis 1,795 | 1,795
ductal carcinoma in situ 1,745 | 1,745
cystic fibrosis 1,665 | 1,665
diabetes mellitus 1,663 | 1,663
breast carcinoma 1,614 | 1,614
tuberculosis 1,557 | 1,557
posterior fossa group B ependymoma 1,530 | 1,530
medulloblastoma 1,524 | 1,524
posterior fossa group A ependymoma 1,511 | 1,511
astrocytoma 1,493 | 1,493
sonic hedgehog group medulloblastoma 1,482 | 1,482
colon cancer 1,475 | 1,475
adrenocortical carcinoma 1,427 | 1,427
Multiple myeloma 1,327 | 1,327
primary pancreatic ductal adenocarcinoma 1,271 | 1,271
juvenile dermatomyositis 1,189 | 1,189
Rheumatoid Arthritis 1,160 | 1,160
acute quadriplegic myopathy 1,157 | 1,157
atypical teratoid/rhabdoid tumor 1,095 | 1,095
spina bifida 1,064 | 1,064
cutaneous lupus erythematosus 1,056 | 1,056
nasopharyngeal carcinoma 1,056 | 1,056
Atopic dermatitis 944 | 944
dermatomyositis 933 | 933
active Crohn's disease 918 | 918
non primary Sjogren syndrome sicca 840 | 840
gastric carcinoma 832 | 832
primary Sjogren syndrome 789 | 789
acute myeloid leukemia 780 | 780
Waldenstrons macroglobulinemia 765 | 765
esophageal adenocarcinoma 737 | 737
tuberculosis and treatment for 6 months 686 | 686
progressive supranuclear palsy 674 | 674
aldosterone-producing adenoma 664 | 664
Alzheimer's disease 644 | 644
Obesity 616 | 616
Duchenne muscular dystrophy 602 | 602
Intellectual disability 573 | 573
pancreatic carcinoma 567 | 567
fibroadenoma 557 | 557
Down syndrome 548 | 548
Endometriosis 535 | 535
hepatocellular carcinoma 532 | 532
chronic rhinosinusitis 512 | 512
Schizophrenia 501 | 501
autosomal dominant Emery-Dreifuss muscular dystrophy 499 | 499
Multiple Sclerosis 498 | 498
mucosa-associated lymphoid tissue lymphoma 480 | 480
active ulcerative colitis 477 | 477
Prostatic Neoplasms 471 | 471
IGA Glomerulonephritis 454 | 454
Amyotrophic Lateral Sclerosis 431 | 431
gastric cancer 430 | 430
non-small cell lung carcinoma 413 | 413
Mammary Neoplasms 410 | 410
inflammatory breast cancer 404 | 404
Kidney disease 396 | 396
Neurodegenerative disease 383 | 383
Parkinson's disease 364 | 364
sarcoidosis 358 | 358
Asthma 349 | 349
glioblastoma multiforme 347 | 347
Epilepsy 346 | 346
Polycystic Ovary Syndrome 332 | 332
nephrosclerosis 329 | 329
tuberculosis and treatment for 3 months 327 | 327
Autistic Disorder 320 | 320

Tissue

Female tissues 266 | 18,647
Blood and immune system 265 | 17,995
Digestive Tract 265 | 18,473
Liver and Pancreas 264 | 18,136
Nervous System 264 | 18,561
Urinary Tract 264 | 18,444
Respiratory system 263 | 17,484
Cardiovascular System 261 | 17,958
Endocrine System 261 | 18,512
Male tissues 261 | 17,969
Skin and soft tissues 261 | 18,115

Target Family

Non-IDG 189 | 11,971
Enzyme 45 | 4,146
Transcription Factor 12 | 1,400
Transporter 9 | 473
Kinase 6 | 634
GPCR 4 | 406
Nuclear Receptor 2 | 48
Epigenetic 1 | 242
Ion Channel 1 | 341

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Proto-oncogene c-Fos FOS Tchem Transcription Factor -4.11560 13094.7 961
Interleukin-1 beta IL1B Tclin Non-IDG -4.34333 22444.2 1345
C-reactive protein CRP Tbio Non-IDG -4.51399 33883.5 1160
Interstitial collagenase MMP1 Tchem Enzyme -3.40801 2529.5 682
Protein THEMIS2 THEMIS2 Tbio Non-IDG -1.15987 17.5 42
Beta-galactoside alpha-2,6-sialyltransferase 1 ST6GAL1 Tchem Enzyme -2.37851 255.2 269
Lymphoid-restricted membrane protein LRMP Tbio Non-IDG -1.17754 15.9 54
Monocarboxylate transporter 9 SLC16A9 Tbio Transporter -0.78270 6.92 47
Fibronectin type III domain-containing protein 3B FNDC3B Tbio Non-IDG -1.29348 21.6 84
Macrophage metalloelastase MMP12 Tchem Enzyme 0.00000 382