Development Level

Tbio 187 | 11,445
Tchem 45 | 1,598
Tdark 34 | 6,588
Tclin 27 | 613

Collection

Kinase: IDG Consortium (Target... 2 | 125
RFA-RM-18-021 2 | 328

IMPC Phenotype

preweaning lethality, complete... 11 | 979
decreased lymphocyte cell numb... 10 | 83
abnormal heart morphology 6 | 162
enlarged heart 6 | 210
increased neutrophil cell numb... 5 | 46
abnormal behavior 4 | 298
abnormal coat-hair pigmentatio... 4 | 64
abnormal lens morphology 4 | 81
cataract 4 | 92
decreased body weight 4 | 161
decreased vertical activity 4 | 208
increased monocyte cell number 4 | 63
preweaning lethality, incomple... 4 | 499
small superior vagus ganglion 4 | 74
abnormal embryo size 3 | 220
abnormal seminal vesicle morph... 3 | 114
abnormal vibrissa morphology 3 | 25
decreased circulating insulin ... 3 | 76
decreased circulating triglyce... 3 | 79
decreased leukocyte cell numbe... 3 | 73
decreased startle reflex 3 | 75
decreased total body fat amoun... 3 | 207
embryonic lethality prior to t... 3 | 278
enlarged seminal vesicle 3 | 10
increased bone mineral content 3 | 108
increased mean corpuscular vol... 3 | 92
increased or absent threshold ... 3 | 101
short tibia 3 | 97
thrombocytopenia 3 | 56
abnormal gait 2 | 69
abnormal kidney morphology 2 | 65
abnormal retina morphology 2 | 71
decreased blood urea nitrogen ... 2 | 51
decreased circulating amylase ... 2 | 28
decreased hemoglobin content 2 | 68
decreased mean corpuscular hem... 2 | 50
decreased prepulse inhibition 2 | 82
embryonic lethality prior to o... 2 | 239
enlarged uterus 2 | 11
hydrometra 2 | 53
hyperactivity 2 | 148
hypoactivity 2 | 132
increased blood urea nitrogen ... 2 | 48
increased circulating alkaline... 2 | 122
increased circulating chloride... 2 | 41
increased circulating sodium l... 2 | 71
increased eosinophil cell numb... 2 | 11
increased erythrocyte cell num... 2 | 39
increased lean body mass 2 | 172
increased mean corpuscular hem... 2 | 96
increased red blood cell distr... 2 | 34
increased spleen weight 2 | 10
increased startle reflex 2 | 112
persistence of hyaloid vascula... 2 | 33
tremors 2 | 39
trunk curl 2 | 16
abnormal cornea morphology 1 | 31
abnormal ear morphology 1 | 9
abnormal epididymis morphology 1 | 42
abnormal heart left ventricle ... 1 | 16
abnormal locomotor activation 1 | 16
abnormal locomotor behavior 1 | 24
abnormal lung morphology 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal sensory capabilities-... 1 | 8
abnormal spleen morphology 1 | 55
abnormal startle reflex 1 | 15
abnormal testis morphology 1 | 43
corneal opacity 1 | 32
decreased circulating bilirubi... 1 | 19
decreased circulating magnesiu... 1 | 13
decreased circulating potassiu... 1 | 20
decreased circulating sodium l... 1 | 22
decreased erythrocyte cell num... 1 | 62
decreased grip strength 1 | 116
decreased lean body mass 1 | 135
decreased mean corpuscular hem... 1 | 31
decreased neutrophil cell numb... 1 | 42
edema 1 | 59
enlarged epididymis 1 | 31
impaired glucose tolerance 1 | 75
impaired pupillary reflex 1 | 26
impaired righting response 1 | 26
increased anti-nuclear antigen... 1 | 19
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating amylase ... 1 | 25
increased circulating fructosa... 1 | 13
increased circulating potassiu... 1 | 29
increased circulating triglyce... 1 | 42
increased fasted circulating g... 1 | 76
increased heart weight 1 | 62
increased hemoglobin content 1 | 45
increased mean platelet volume 1 | 45
microphthalmia 1 | 26
small testis 1 | 58
stereotypic behavior 1 | 3
thin ventricular wall 1 | 24
urinary bladder obstruction 1 | 4
vertebral fusion 1 | 23

Disease

periodontitis 293 | 293
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Blood and immune system 271 | 16,909
Female tissues 271 | 17,400
Digestive Tract 270 | 17,369
Skin and soft tissues 269 | 17,230
Endocrine System 265 | 18,159
Male tissues 260 | 17,142
Urinary Tract 258 | 16,678
Liver and Pancreas 256 | 16,750
Respiratory system 254 | 16,393
Nervous System 245 | 16,725
Cardiovascular System 226 | 15,192

Target Family

Non-IDG 205 | 12,091
Enzyme 50 | 4,145
Transcription Factor 14 | 1,400
Transporter 10 | 473
Kinase 6 | 634
GPCR 4 | 408
Nuclear Receptor 2 | 48
Epigenetic 1 | 242
Ion Channel 1 | 344

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Collagen alpha-1(IV) chain COL4A1 Tbio Non-IDG -2.28595 186.9 391
Arylacetamide deacetylase-like 2 AADACL2 Tdark Enzyme 0.41 0.15 90
Alpha-1-antitrypsin SERPINA1 Tbio Non-IDG -3.74914 5601.8 1083
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 CD38 Tclin Enzyme -3.44680 2663.1 1493
CD40 ligand CD40LG Tbio Non-IDG -4.58203 37578.3 1461
CAP-Gly domain-containing linker protein 1 CLIP1 Tbio Non-IDG -2.54943 343.7 221
Lysosomal-trafficking regulator LYST Tbio Non-IDG -1.96473 92.5 15
T-lymphocyte surface antigen Ly-9 LY9 Tbio Non-IDG -1.58527 43.8 383
Marginal zone B- and B1-cell-specific protein MZB1 Tbio Non-IDG -1.11106 17.1 71
Protein FAM83C FAM83C Tdark Non-IDG 0.18 0.56 4