Development Level

Tbio 1,920 | 11,445
Tdark 498 | 6,588
Tchem 304 | 1,598
Tclin 128 | 613

Collection

RFA-RM-18-021 59 | 328
Ion Channel: IDG Consortium (T... 26 | 99
Kinase: IDG Consortium (Target... 24 | 125
GPCR: IDG Consortium (Targets) 11 | 126
Kinase: IDG Consortium (Comple... 8 | 37
GPCR: IDG Consortium (Complete... 4 | 25

IMPC Phenotype

preweaning lethality, complete... 159 | 979
preweaning lethality, incomple... 113 | 499
abnormal behavior 85 | 298
decreased total body fat amoun... 48 | 207
embryonic lethality prior to t... 46 | 278
hyperactivity 43 | 148
decreased vertical activity 41 | 208
abnormal embryo size 40 | 220
increased lean body mass 38 | 172
abnormal bone structure 35 | 187
enlarged heart 35 | 210
hypoactivity 33 | 132
embryonic lethality prior to o... 31 | 239
decreased circulating glucose ... 28 | 126
increased circulating alkaline... 28 | 122
abnormal heart morphology 27 | 162
decreased bone mineral content 27 | 151
increased bone mineral content 27 | 108
decreased circulating choleste... 26 | 93
decreased grip strength 26 | 116
abnormal seminal vesicle morph... 25 | 114
decreased body weight 25 | 161
decreased lean body mass 24 | 135
increased total body fat amoun... 22 | 134
embryonic growth retardation 21 | 106
increased startle reflex 21 | 112
abnormal gait 18 | 69
decreased bone mineral density 18 | 126
decreased circulating HDL chol... 18 | 68
decreased circulating insulin ... 18 | 76
decreased circulating serum al... 18 | 82
decreased lymphocyte cell numb... 18 | 83
edema 18 | 59
increased or absent threshold ... 18 | 101
prenatal lethality prior to he... 18 | 87
abnormal eye morphology 17 | 68
abnormal sleep behavior 17 | 70
decreased startle reflex 17 | 75
short tibia 17 | 97
cataract 16 | 92
increased circulating triglyce... 16 | 42
increased monocyte cell number 16 | 63
male infertility 16 | 123
abnormal lens morphology 15 | 81
decreased body length 15 | 101
decreased circulating triglyce... 15 | 79
improved glucose tolerance 15 | 79
increased mean corpuscular vol... 15 | 92
small testis 15 | 58
abnormal coat-hair pigmentatio... 14 | 64
abnormal testis morphology 14 | 43
increased bone mineral density 14 | 72
abnormal retina morphology 13 | 71
decreased leukocyte cell numbe... 13 | 73
increased fasted circulating g... 13 | 76
increased hematocrit 13 | 46
abnormal behavioral response t... 12 | 66
abnormal kidney morphology 12 | 65
decreased fasted circulating g... 12 | 65
increased circulating sodium l... 12 | 71
increased heart weight 12 | 62
increased mean corpuscular hem... 12 | 96
decreased hemoglobin content 11 | 68
decreased neutrophil cell numb... 11 | 42
decreased prepulse inhibition 11 | 82
enlarged spleen 11 | 41
increased blood urea nitrogen ... 11 | 48
increased circulating calcium ... 11 | 34
increased circulating chloride... 11 | 41
limb grasping 11 | 41
abnormal epididymis morphology 10 | 42
abnormal skin morphology 10 | 50
decreased circulating LDL chol... 10 | 38
decreased circulating calcium ... 10 | 36
decreased circulating total pr... 10 | 49
decreased erythrocyte cell num... 10 | 62
decreased mean corpuscular hem... 10 | 31
increased neutrophil cell numb... 10 | 46
increased red blood cell distr... 10 | 34
small superior vagus ganglion 10 | 74
tremors 10 | 39
cardiovascular system phenotyp... 9 | 36
decreased caudal vertebrae num... 9 | 53
decreased mean corpuscular vol... 9 | 79
enlarged epididymis 9 | 31
increased circulating creatini... 9 | 38
increased erythrocyte cell num... 9 | 39
increased hemoglobin content 9 | 45
increased mean corpuscular hem... 9 | 36
increased prepulse inhibition 9 | 32
abnormal craniofacial morpholo... 8 | 33
abnormal lung morphology 8 | 26
abnormal spleen morphology 8 | 55
decreased circulating alkaline... 8 | 46
enlarged kidney 8 | 14
enlarged lymph nodes 8 | 37
impaired glucose tolerance 8 | 75
increased circulating choleste... 8 | 66
increased mean platelet volume 8 | 45
thrombocytopenia 8 | 56

Disease

oligodendroglioma 2,850 | 2,850
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Nervous System 2,827 | 16,725
Endocrine System 2,816 | 18,159
Female tissues 2,782 | 17,400
Digestive Tract 2,781 | 17,369
Skin and soft tissues 2,773 | 17,230
Male tissues 2,765 | 17,142
Liver and Pancreas 2,729 | 16,750
Urinary Tract 2,726 | 16,678
Blood and immune system 2,722 | 16,909
Respiratory system 2,690 | 16,393
Cardiovascular System 2,563 | 15,192

Target Family

Non-IDG 1,680 | 12,091
Enzyme 585 | 4,145
Transcription Factor 181 | 1,400
Kinase 126 | 634
Ion Channel 91 | 344
Transporter 70 | 473
GPCR 55 | 408
Epigenetic 49 | 242
Nuclear Receptor 7 | 48
TF/Epigenetic 6 | 38

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Potassium voltage-gated channel subfamily A member 2 KCNA2 Tclin Ion Channel -2.55550 343.3 205
Hexosaminidase D HEXDC Tbio Enzyme -0.60206 3.83 63
Zinc finger protein 160 ZNF160 Tdark Transcription Factor -0.67261 4.33 63
Septin-11 SEPT11 Tbio Non-IDG -1.47747 32.4 127
Tubulin beta-4A chain TUBB4A Tclin Non-IDG -2.98371 896.1 90
Metabotropic glutamate receptor 5 GRM5 Tchem GPCR -3.12353 1370.3 396
Anaphase-promoting complex subunit 2 ANAPC2 Tbio Enzyme -0.45557 2.44 166
Rab-3A-interacting protein RAB3IP Tbio Non-IDG -1.03500 11.6 89
Sorcin SRI Tbio Non-IDG -2.69915 481.5 119
Protein NipSnap homolog 3B NIPSNAP3B Tbio Non-IDG -1.06487 11.0 103