Development Level

Tbio 37 | 11,651
Tclin 14 | 612
Tchem 5 | 1,388
Tdark 5 | 6,593

Collection

GPCR: IDG Consortium (Targets) 1 | 126
RFA-RM-18-021 1 | 328

IMPC Phenotype

decreased total body fat amoun... 4 | 207
decreased body weight 3 | 161
decreased circulating choleste... 3 | 93
preweaning lethality, complete... 3 | 979
preweaning lethality, incomple... 3 | 499
abnormal behavior 2 | 298
abnormal coat-hair pigmentatio... 2 | 64
decreased circulating HDL chol... 2 | 68
decreased circulating fructosa... 2 | 30
decreased circulating serum al... 2 | 82
decreased lean body mass 2 | 135
hyperactivity 2 | 148
increased circulating sodium l... 2 | 71
abnormal behavioral response t... 1 | 66
abnormal clavicle morphology 1 | 6
abnormal cranium morphology 1 | 36
abnormal epididymis morphology 1 | 42
abnormal locomotor behavior 1 | 24
abnormal maxilla morphology 1 | 17
abnormal seminal vesicle morph... 1 | 114
abnormal snout morphology 1 | 23
abnormal testis morphology 1 | 43
abnormal tooth morphology 1 | 24
absent pinna reflex 1 | 23
decreased anxiety-related resp... 1 | 12
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased circulating creatine... 1 | 4
decreased circulating glucose ... 1 | 126
decreased circulating phosphat... 1 | 27
decreased circulating total pr... 1 | 49
decreased erythrocyte cell num... 1 | 62
decreased grip strength 1 | 116
decreased heart weight 1 | 27
decreased hemoglobin content 1 | 68
decreased lumbar vertebrae num... 1 | 2
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
decreased pulmonary respirator... 1 | 5
decreased startle reflex 1 | 75
decreased vertical activity 1 | 208
enlarged epididymis 1 | 31
impaired glucose tolerance 1 | 75
improved glucose tolerance 1 | 79
increased circulating alanine ... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating chloride... 1 | 41
increased circulating creatine... 1 | 5
increased circulating iron lev... 1 | 30
increased fasted circulating g... 1 | 76
increased lean body mass 1 | 172
increased neutrophil cell numb... 1 | 46
increased startle reflex 1 | 112
limb grasping 1 | 41
small heart 1 | 10
small testis 1 | 58
thrombocytosis 1 | 27
vertebral fusion 1 | 23

Disease

obsessive-compulsive disorder 61 | 61
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Endocrine System 60 | 18,159
Female tissues 60 | 17,400
Nervous System 58 | 16,725
Skin and soft tissues 58 | 17,230
Male tissues 57 | 17,142
Digestive Tract 56 | 17,369
Liver and Pancreas 56 | 16,750
Respiratory system 53 | 16,393
Urinary Tract 53 | 16,678
Blood and immune system 52 | 16,909
Cardiovascular System 44 | 15,192

Target Family

Non-IDG 27 | 12,091
GPCR 10 | 408
Enzyme 8 | 4,145
Transcription Factor 5 | 1,400
Epigenetic 4 | 242
Transporter 4 | 473
Ion Channel 2 | 344
Kinase 1 | 634

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
SET domain-containing protein 5 SETD5 Tbio Epigenetic -0.91515 9.39 43
Sodium-dependent serotonin transporter SLC6A4 Tclin Transporter -3.63283 4453.8 245
Ankyrin repeat and SOCS box protein 13 ASB13 Tdark Non-IDG 0.78 0.14 85
5-hydroxytryptamine receptor 2C HTR2C Tclin GPCR -3.08158 1199.3 336
Inositol polyphosphate 5-phosphatase OCRL-1 OCRL Tbio Enzyme -2.20394 172.2 226
D(2) dopamine receptor DRD2 Tclin GPCR -3.28700 1882.2 264
Semaphorin-3E SEMA3E Tbio Non-IDG -1.62878 48.9 219
Gamma-tubulin complex component 5 TUBGCP5 Tbio Non-IDG -0.81376 5.88 99
Nipped-B-like protein NIPBL Tbio Non-IDG -2.25874 186.3 134
LIM domain kinase 1 LIMK1 Tchem Kinase -2.28919 187.7 664