Development Level

Tbio 147 | 10,625
Tdark 35 | 7,003
Tchem 21 | 1,890
Tclin 5 | 602

Collection

Eligible non-olfactory GPCR Proteins 2 | 143
Eligible Ion Channel Proteins 1 | 117

IMPC Term

decreased total body fat amoun... 8 | 186
increased bone mineral content 6 | 92
increased circulating alkaline... 6 | 119
increased lean body mass 6 | 107
decreased circulating insulin ... 5 | 75
abnormal behavior 4 | 226
decreased lean body mass 4 | 195
abnormal bone structure 3 | 131
abnormal kidney morphology 3 | 30
abnormal seminal vesicle morph... 3 | 47
decreased circulating triglyce... 3 | 83
preweaning lethality, complete... 3 | 633
preweaning lethality, incomple... 3 | 260
abnormal coat/ hair morphology 2 | 18
abnormal heart morphology 2 | 51
abnormal response to tactile s... 2 | 16
abnormal testis morphology 2 | 30
abnormal vibrissa morphology 2 | 17
decreased T cell number 2 | 31
decreased body weight 2 | 174
decreased bone mineral content 2 | 157
decreased bone mineral density 2 | 126
decreased caudal vertebrae num... 2 | 49
decreased circulating HDL chol... 2 | 77
decreased circulating LDL chol... 2 | 37
decreased circulating choleste... 2 | 85
decreased circulating serum al... 2 | 79
decreased fasted circulating g... 2 | 49
enlarged heart 2 | 111
hypoactivity 2 | 89
impaired glucose tolerance 2 | 52
increased circulating total pr... 2 | 20
increased or absent threshold ... 2 | 128
small testis 2 | 37
abnormal digit morphology 1 | 13
abnormal embryo size 1 | 112
abnormal forelimb morphology 1 | 2
abnormal gait 1 | 51
abnormal liver morphology 1 | 5
abnormal lymph node morphology 1 | 3
abnormal motor learning 1 | 4
abnormal skin morphology 1 | 23
abnormal sleep behavior 1 | 63
abnormal spleen morphology 1 | 36
abnormal tibia morphology 1 | 14
absent vibrissae 1 | 14
cataract 1 | 26
corneal opacity 1 | 25
decreased CD4-positive, alpha ... 1 | 19
decreased IgE level 1 | 3
decreased IgG1 level 1 | 4
decreased circulating alanine ... 1 | 53
decreased circulating alkaline... 1 | 41
decreased circulating aspartat... 1 | 27
decreased circulating chloride... 1 | 32
decreased circulating fructosa... 1 | 31
decreased circulating glucose ... 1 | 121
decreased circulating total pr... 1 | 41
decreased effector memory CD8-... 1 | 24
decreased grip strength 1 | 123
decreased hemoglobin content 1 | 53
decreased startle reflex 1 | 48
embryonic lethality prior to o... 1 | 148
embryonic lethality prior to t... 1 | 187
enlarged heart atrium 1 | 2
enlarged kidney 1 | 7
enlarged spleen 1 | 26
female infertility 1 | 34
improved glucose tolerance 1 | 56
increased B cell number 1 | 23
increased bone mineral density 1 | 52
increased circulating chloride... 1 | 43
increased circulating creatini... 1 | 29
increased circulating free fat... 1 | 17
increased circulating magnesiu... 1 | 10
increased circulating sodium l... 1 | 71
increased grip strength 1 | 83
increased mature B cell number 1 | 12
increased mean corpuscular hem... 1 | 93
increased rib number 1 | 41
increased startle reflex 1 | 38
increased total body fat amoun... 1 | 57
increased vertical activity 1 | 18
limb grasping 1 | 35
prenatal lethality prior to he... 1 | 64
short tibia 1 | 82
shortened ST segment 1 | 9
small thymus 1 | 11
syndactyly 1 | 4
tremors 1 | 34

Disease

non-inflammatory breast cancer 208 | 208
ovarian cancer 8,484 | 8,484
osteosarcoma 7,933 | 7,933
psoriasis 6,685 | 6,685
medulloblastoma, large-cell 6,234 | 6,234
glioblastoma 5,572 | 5,572
lung cancer 4,466 | 4,466
atypical teratoid / rhabdoid tumor 4,369 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 3,289 | 3,289
malignant mesothelioma 3,162 | 3,162
Breast cancer 3,094 | 3,094
pilocytic astrocytoma 3,086 | 3,086
primitive neuroectodermal tumor 3,031 | 3,031
intraductal papillary-mucinous carcinoma (IPMC) 2,988 | 2,988
intraductal papillary-mucinous adenoma (IPMA) 2,956 | 2,956
invasive ductal carcinoma 2,950 | 2,950
oligodendroglioma 2,849 | 2,849
lung carcinoma 2,844 | 2,844
non-small cell lung cancer 2,798 | 2,798
lung adenocarcinoma 2,713 | 2,713
pediatric high grade glioma 2,712 | 2,712
ependymoma 2,514 | 2,514
Cancer 2,346 | 2,346
pancreatic cancer 2,300 | 2,300
interstitial cystitis 2,299 | 2,299
subependymal giant cell astrocytoma 2,287 | 2,287
group 3 medulloblastoma 2,254 | 2,254
astrocytic glioma 2,241 | 2,241
adult high grade glioma 2,148 | 2,148
Carcinoma 2,147 | 2,147
ulcerative colitis 2,087 | 2,087
pituitary cancer 1,972 | 1,972
Pick disease 1,893 | 1,893
group 4 medulloblastoma 1,875 | 1,875
pancreatic ductal adenocarcinoma liver metastasis 1,795 | 1,795
ductal carcinoma in situ 1,745 | 1,745
cystic fibrosis 1,665 | 1,665
diabetes mellitus 1,663 | 1,663
breast carcinoma 1,614 | 1,614
tuberculosis 1,557 | 1,557
posterior fossa group B ependymoma 1,530 | 1,530
medulloblastoma 1,524 | 1,524
posterior fossa group A ependymoma 1,511 | 1,511
astrocytoma 1,493 | 1,493
sonic hedgehog group medulloblastoma 1,482 | 1,482
colon cancer 1,475 | 1,475
adrenocortical carcinoma 1,427 | 1,427
Multiple myeloma 1,327 | 1,327
primary pancreatic ductal adenocarcinoma 1,271 | 1,271
juvenile dermatomyositis 1,189 | 1,189
Rheumatoid Arthritis 1,160 | 1,160
acute quadriplegic myopathy 1,157 | 1,157
atypical teratoid/rhabdoid tumor 1,095 | 1,095
spina bifida 1,064 | 1,064
cutaneous lupus erythematosus 1,056 | 1,056
nasopharyngeal carcinoma 1,056 | 1,056
Atopic dermatitis 944 | 944
dermatomyositis 933 | 933
active Crohn's disease 918 | 918
non primary Sjogren syndrome sicca 840 | 840
gastric carcinoma 832 | 832
primary Sjogren syndrome 789 | 789
acute myeloid leukemia 780 | 780
Waldenstrons macroglobulinemia 765 | 765
esophageal adenocarcinoma 737 | 737
tuberculosis and treatment for 6 months 686 | 686
progressive supranuclear palsy 674 | 674
aldosterone-producing adenoma 664 | 664
Alzheimer's disease 644 | 644
Obesity 616 | 616
Duchenne muscular dystrophy 602 | 602
Intellectual disability 573 | 573
pancreatic carcinoma 567 | 567
fibroadenoma 557 | 557
Down syndrome 548 | 548
Endometriosis 535 | 535
hepatocellular carcinoma 532 | 532
chronic rhinosinusitis 512 | 512
Schizophrenia 501 | 501
autosomal dominant Emery-Dreifuss muscular dystrophy 499 | 499
Multiple Sclerosis 498 | 498
mucosa-associated lymphoid tissue lymphoma 480 | 480
active ulcerative colitis 477 | 477
Prostatic Neoplasms 471 | 471
IGA Glomerulonephritis 454 | 454
Amyotrophic Lateral Sclerosis 431 | 431
gastric cancer 430 | 430
non-small cell lung carcinoma 413 | 413
Mammary Neoplasms 410 | 410
inflammatory breast cancer 404 | 404
Kidney disease 396 | 396
Neurodegenerative disease 383 | 383
Parkinson's disease 364 | 364
sarcoidosis 358 | 358
Asthma 349 | 349
glioblastoma multiforme 347 | 347
Epilepsy 346 | 346
Polycystic Ovary Syndrome 332 | 332
nephrosclerosis 329 | 329
tuberculosis and treatment for 3 months 327 | 327
Autistic Disorder 320 | 320

Tissue

Nervous System 207 | 18,561
Urinary Tract 206 | 18,444
Cardiovascular System 205 | 17,958
Digestive Tract 205 | 18,473
Female tissues 205 | 18,647
Endocrine System 204 | 18,512
Liver and Pancreas 204 | 18,136
Blood and immune system 203 | 17,995
Male tissues 203 | 17,969
Skin and soft tissues 202 | 18,115
Respiratory system 201 | 17,484

Target Family

Non-IDG 128 | 11,971
Enzyme 43 | 4,146
Transcription Factor 16 | 1,400
GPCR 7 | 406
Ion Channel 5 | 341
Kinase 4 | 634
Transporter 3 | 473
Epigenetic 2 | 242

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Histone deacetylase 5 HDAC5 Tclin Epigenetic -2.11372 127.6 466
Ropporin-1B ROPN1B Tbio Non-IDG 1.00 0.10 52
Glutathione S-transferase A5 GSTA5 Tdark Enzyme -1.03093 10.6 28
Tenascin-N TNN Tbio Non-IDG -1.77329 68.8 63
Krueppel-like factor 9 KLF9 Tbio Transcription Factor -1.87911 88.8 139
Pyrroline-5-carboxylate reductase 3 PYCRL Tbio Enzyme 0.14 0.58 97
Serotransferrin TF Tchem Non-IDG -4.13136 13124.3 952
Filamin-interacting protein FAM101A RFLNA Tbio Non-IDG -0.95944 9.37 82
Adhesion G protein-coupled receptor A3 ADGRA3 Tbio GPCR -0.92696 10.7 107
Endothelin B receptor EDNRB Tclin GPCR -3.24561 1672.0 289