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Development Level

Tbio 594 | 11,445
Tdark 189 | 6,588
Tchem 73 | 1,598
Tclin 35 | 613

Collection

RFA-RM-18-021 9 | 328
Ion Channel: IDG Consortium (T... 5 | 99
GPCR: IDG Consortium (Targets) 3 | 126
GPCR: IDG Consortium (Complete... 1 | 25
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 55 | 979
preweaning lethality, incomple... 22 | 499
abnormal embryo size 19 | 220
embryonic lethality prior to t... 18 | 278
embryonic lethality prior to o... 16 | 239
decreased total body fat amoun... 14 | 207
enlarged heart 13 | 210
decreased body weight 12 | 161
decreased vertical activity 11 | 208
increased circulating alkaline... 11 | 122
abnormal behavior 10 | 298
abnormal heart morphology 10 | 162
increased lean body mass 10 | 172
abnormal bone structure 9 | 187
abnormal coat-hair pigmentatio... 9 | 64
decreased circulating glucose ... 8 | 126
embryonic growth retardation 8 | 106
hyperactivity 8 | 148
increased circulating HDL chol... 8 | 80
prenatal lethality prior to he... 8 | 87
cataract 7 | 92
decreased circulating choleste... 7 | 93
decreased circulating serum al... 7 | 82
increased circulating choleste... 7 | 66
increased heart weight 7 | 62
increased startle reflex 7 | 112
increased total body fat amoun... 7 | 134
male infertility 7 | 123
abnormal lens morphology 6 | 81
decreased body length 6 | 101
decreased bone mineral density 6 | 126
decreased circulating HDL chol... 6 | 68
decreased circulating triglyce... 6 | 79
increased bone mineral density 6 | 72
increased or absent threshold ... 6 | 101
short tibia 6 | 97
abnormal eye morphology 5 | 68
abnormal skin morphology 5 | 50
decreased bone mineral content 5 | 151
decreased erythrocyte cell num... 5 | 62
small superior vagus ganglion 5 | 74
abnormal kidney morphology 4 | 65
abnormal retinal blood vessel ... 4 | 26
decreased circulating calcium ... 4 | 36
decreased circulating insulin ... 4 | 76
decreased grip strength 4 | 116
decreased lean body mass 4 | 135
decreased startle reflex 4 | 75
impaired glucose tolerance 4 | 75
impaired pupillary reflex 4 | 26
increased circulating chloride... 4 | 41
increased circulating sodium l... 4 | 71
increased mean corpuscular vol... 4 | 92
limb grasping 4 | 41
abnormal bone mineralization 3 | 38
abnormal gait 3 | 69
abnormal neural tube closure 3 | 46
abnormal seminal vesicle morph... 3 | 114
abnormal tooth morphology 3 | 24
absent startle reflex 3 | 24
decreased T cell number 3 | 15
decreased circulating LDL chol... 3 | 38
decreased circulating alanine ... 3 | 47
decreased circulating chloride... 3 | 30
decreased circulating total pr... 3 | 49
decreased heart left ventricle... 3 | 28
decreased neutrophil cell numb... 3 | 42
decreased prepulse inhibition 3 | 82
enlarged lymph nodes 3 | 37
female infertility 3 | 60
hypoactivity 3 | 132
increased blood urea nitrogen ... 3 | 48
increased bone mineral content 3 | 108
increased circulating amylase ... 3 | 25
increased circulating bilirubi... 3 | 16
increased circulating creatini... 3 | 38
increased grip strength 3 | 41
increased leukocyte cell numbe... 3 | 47
increased mean corpuscular hem... 3 | 36
pale yolk sac 3 | 25
pallor 3 | 34
small adrenal glands 3 | 16
abnormal cornea morphology 2 | 31
abnormal liver morphology 2 | 17
abnormal placenta size 2 | 20
abnormal retina morphology 2 | 71
anophthalmia 2 | 33
cardiovascular system phenotyp... 2 | 36
corneal opacity 2 | 32
decreased eosinophil cell numb... 2 | 24
decreased fasted circulating g... 2 | 65
decreased hematocrit 2 | 46
decreased hemoglobin content 2 | 68
increased circulating calcium ... 2 | 34
increased circulating serum al... 2 | 22
increased fasted circulating g... 2 | 76
increased hematocrit 2 | 46
increased mean platelet volume 2 | 45
increased monocyte cell number 2 | 63
small testis 2 | 58

Disease

non primary Sjogren syndrome sicca 891 | 891
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Endocrine System 872 | 18,159
Digestive Tract 860 | 17,369
Female tissues 858 | 17,400
Skin and soft tissues 852 | 17,230
Male tissues 851 | 17,142
Blood and immune system 847 | 16,909
Liver and Pancreas 845 | 16,750
Urinary Tract 843 | 16,678
Nervous System 838 | 16,725
Respiratory system 832 | 16,393
Cardiovascular System 787 | 15,192

Target Family

Non-IDG 515 | 12,091
Enzyme 223 | 4,145
Transcription Factor 60 | 1,400
Transporter 28 | 473
Kinase 22 | 634
Ion Channel 18 | 344
GPCR 10 | 408
Epigenetic 8 | 242
oGPCR 4 | 421
Nuclear Receptor 2 | 48
TF/Epigenetic 1 | 38

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Mitochondrial coenzyme A transporter SLC25A42 SLC25A42 Tbio Transporter -0.53750 4.06 29
Protein unc-13 homolog D UNC13D Tbio Non-IDG -1.93790 85.1 158
Protein S100-A11 S100A11 Tbio Non-IDG -2.01412 110.0 311
Zinc finger protein 99 ZNF99 Tdark Transcription Factor 1.38 0.03 50
Cell division cycle protein 23 homolog CDC23 Tbio Non-IDG -1.50528 30.4 191
Redox-regulatory protein FAM213A FAM213A Tbio Non-IDG -1.51277 30.6 63
Four and a half LIM domains protein 1 FHL1 Tbio Non-IDG -2.46134 291.4 312
Leucine-rich repeat-containing protein 63 LRRC63 Tdark Non-IDG 1.04 0.03 0
Mini-chromosome maintenance complex-binding protein MCMBP Tbio Non-IDG -0.65233 5.60 92
Tyrosine-protein phosphatase non-receptor type 18 PTPN18 Tbio Enzyme -0.77241 5.46 77