Development Level

Tbio 121 | 11,178
Tdark 38 | 6,569
Tchem 30 | 1,885
Tclin 6 | 612

Collection

GPCR: IDG Consortium (Targets) 1 | 126

IMPC Phenotype

preweaning lethality, complete... 10 | 979
preweaning lethality, incomple... 8 | 499
abnormal behavior 6 | 298
abnormal heart morphology 4 | 162
enlarged heart 4 | 210
hyperactivity 4 | 148
decreased circulating glucose ... 3 | 126
decreased lean body mass 3 | 135
increased bone mineral density 3 | 72
increased circulating triglyce... 3 | 42
increased total body fat amoun... 3 | 134
limb grasping 3 | 41
abnormal behavioral response t... 2 | 66
abnormal embryo size 2 | 220
abnormal epididymis morphology 2 | 42
abnormal lung morphology 2 | 26
abnormal seminal vesicle morph... 2 | 114
abnormal sleep behavior 2 | 70
decreased bone mineral content 2 | 151
decreased circulating bilirubi... 2 | 19
decreased circulating insulin ... 2 | 76
decreased grip strength 2 | 116
decreased leukocyte cell numbe... 2 | 73
decreased mean corpuscular vol... 2 | 79
decreased total body fat amoun... 2 | 207
decreased vertical activity 2 | 208
embryonic lethality prior to t... 2 | 278
enlarged epididymis 2 | 31
impaired righting response 2 | 26
increased bone mineral content 2 | 108
increased circulating HDL chol... 2 | 80
increased circulating choleste... 2 | 66
increased circulating iron lev... 2 | 30
increased circulating sodium l... 2 | 71
increased hematocrit 2 | 46
increased hemoglobin content 2 | 45
increased mean corpuscular vol... 2 | 92
increased red blood cell distr... 2 | 34
thrombocytosis 2 | 27
abnormal bone mineralization 1 | 38
abnormal coat-hair pigmentatio... 1 | 64
abnormal cornea morphology 1 | 31
abnormal eye morphology 1 | 68
abnormal facial morphology 1 | 17
abnormal head shape 1 | 10
abnormal joint morphology 1 | 23
abnormal lens morphology 1 | 81
abnormal limb morphology 1 | 13
abnormal liver morphology 1 | 17
abnormal lymph node morphology 1 | 3
abnormal spleen morphology 1 | 55
abnormal tail morphology 1 | 25
abnormal testis morphology 1 | 43
abnormal tooth morphology 1 | 24
abnormal vertebral arch morpho... 1 | 9
anophthalmia 1 | 33
brachydactyly 1 | 19
cataract 1 | 92
decreased blood urea nitrogen ... 1 | 51
decreased bone mineral density 1 | 126
decreased circulating amylase ... 1 | 28
decreased circulating chloride... 1 | 30
decreased circulating fructosa... 1 | 30
decreased circulating iron lev... 1 | 32
decreased circulating phosphat... 1 | 27
decreased circulating serum al... 1 | 82
decreased circulating triglyce... 1 | 79
decreased fasted circulating g... 1 | 65
decreased mean corpuscular hem... 1 | 31
decreased red blood cell distr... 1 | 41
edema 1 | 59
enlarged heart atrium 1 | 4
enlarged spleen 1 | 41
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
impaired pupillary reflex 1 | 26
improved glucose tolerance 1 | 79
increased anti-nuclear antigen... 1 | 19
increased body weight 1 | 25
increased circulating alanine ... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating bilirubi... 1 | 16
increased circulating potassiu... 1 | 29
increased eosinophil cell numb... 1 | 11
increased large unstained cell... 1 | 5
increased lean body mass 1 | 172
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 96
increased prepulse inhibition 1 | 32
increased vertical activity 1 | 24
long tibia 1 | 25
male infertility 1 | 123
microphthalmia 1 | 26
persistence of hyaloid vascula... 1 | 33
shortened PQ interval 1 | 7
small seminal vesicle 1 | 10
small testis 1 | 58
syndactyly 1 | 23
vertebral fusion 1 | 23

Disease

non diabetic and post-ischemic heart failure 195 | 195
Carcinoma 11,192 | 11,192
ovarian cancer 8,297 | 8,297
osteosarcoma 7,766 | 7,766
psoriasis 6,514 | 6,514
medulloblastoma, large-cell 6,086 | 6,086
glioblastoma 5,635 | 5,635
atypical teratoid / rhabdoid tumor 4,971 | 4,971
lung cancer 4,607 | 4,607
ependymoma 4,559 | 4,559
group 3 medulloblastoma 4,002 | 4,002
adult high grade glioma 3,701 | 3,701
Breast cancer 3,469 | 3,469
intraductal papillary-mucinous neoplasm (IPMN) 3,204 | 3,204
malignant mesothelioma 3,135 | 3,135
Astrocytoma, Pilocytic 3,006 | 3,006
primitive neuroectodermal tumor 2,957 | 2,957
intraductal papillary-mucinous carcinoma (IPMC) 2,902 | 2,902
intraductal papillary-mucinous adenoma (IPMA) 2,872 | 2,872
invasive ductal carcinoma 2,867 | 2,867
non-small cell lung cancer 2,799 | 2,799
oligodendroglioma 2,768 | 2,768
lung carcinoma 2,755 | 2,755
lung adenocarcinoma 2,627 | 2,627
Kidney cancer 2,548 | 2,548
astrocytic glioma 2,530 | 2,530
Cancer 2,388 | 2,388
pancreatic cancer 2,322 | 2,322
interstitial cystitis 2,237 | 2,237
subependymal giant cell astrocytoma 2,230 | 2,230
tuberculosis 1,963 | 1,963
pituitary cancer 1,915 | 1,915
pancreatic ductal adenocarcinoma liver metastasis 1,911 | 1,911
Pick disease 1,856 | 1,856
group 4 medulloblastoma 1,806 | 1,806
ulcerative colitis 1,765 | 1,765
ductal carcinoma in situ 1,686 | 1,686
diabetes mellitus 1,683 | 1,683
cystic fibrosis 1,629 | 1,629
breast carcinoma 1,589 | 1,589
colon cancer 1,428 | 1,428
Autosomal recessive predisposition 1,407 | 1,407
adrenocortical carcinoma 1,385 | 1,385
Multiple myeloma 1,296 | 1,296
Rheumatoid arthritis 1,156 | 1,156
juvenile dermatomyositis 1,147 | 1,147
Schizophrenia 1,136 | 1,136
acute quadriplegic myopathy 1,133 | 1,133
astrocytoma 1,113 | 1,113
primary pancreatic ductal adenocarcinoma 1,071 | 1,071
spina bifida 1,053 | 1,053
pediatric high grade glioma 1,035 | 1,035
nasopharyngeal carcinoma 1,024 | 1,024
cutaneous lupus erythematosus 1,016 | 1,016
Intellectual disability 998 | 998
dermatomyositis 941 | 941
Atopic dermatitis 915 | 915
active Crohn's disease 882 | 882
non primary Sjogren syndrome sicca 861 | 861
gastric carcinoma 781 | 781
Epilepsy 775 | 775
acute myeloid leukemia 760 | 760
Waldenstrons macroglobulinemia 742 | 742
active ulcerative colitis 736 | 736
Liver Cirrhosis, Experimental 733 | 733
primary Sjogren syndrome 710 | 710
medulloblastoma 702 | 702
esophageal adenocarcinoma 696 | 696
Melanoma 689 | 689
progressive supranuclear palsy 656 | 656
Obesity 655 | 655
Bipolar Disorder 646 | 646
aldosterone-producing adenoma 646 | 646
Alzheimer's disease 640 | 640
Dull intelligence 634 | 634
Low intelligence 634 | 634
Mental Retardation 634 | 634
Mental deficiency 634 | 634
Poor school performance 634 | 634
Cognitive delay 596 | 596
Global developmental delay 596 | 596
Mental and motor retardation 596 | 596
Liver cancer 589 | 589
Duchenne muscular dystrophy 587 | 587
Seizures 584 | 584
Muscle hypotonia 562 | 562
pancreatic carcinoma 555 | 555
fibroadenoma 538 | 538
hepatocellular carcinoma 536 | 536
Multiple Sclerosis 527 | 527
Endometriosis 521 | 521
Short stature 514 | 514
chronic rhinosinusitis 505 | 505
autosomal dominant Emery-Dreifuss muscular dystrophy 492 | 492
Down syndrome 480 | 480
mucosa-associated lymphoid tissue lymphoma 473 | 473
Prostatic Neoplasms 472 | 472
sonic hedgehog group medulloblastoma 459 | 459
posterior fossa group A ependymoma 456 | 456
Skin cancer 451 | 451
gastric cancer 445 | 445

Tissue

Endocrine System 189 | 18,159
Digestive Tract 188 | 17,369
Skin and soft tissues 187 | 17,230
Female tissues 186 | 17,400
Male tissues 185 | 17,142
Cardiovascular System 184 | 15,192
Liver and Pancreas 184 | 16,750
Nervous System 182 | 16,725
Blood and immune system 181 | 16,909
Urinary Tract 181 | 16,678
Respiratory system 180 | 16,393

Target Family

Non-IDG 124 | 12,091
Enzyme 42 | 4,145
Transporter 8 | 473
GPCR 5 | 408
Kinase 4 | 634
Transcription Factor 4 | 1,400
Ion Channel 2 | 344
TF/Epigenetic 2 | 38
oGPCR 2 | 421
Epigenetic 1 | 242
Nuclear Receptor 1 | 48

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protocadherin-7 PCDH7 Tbio Non-IDG -1.42056 26.3 248
Sarcolipin SLN Tbio Non-IDG -2.17996 148.2 53
RING finger protein 122 RNF122 Tdark Non-IDG -0.44196 3.01 130
Dual specificity protein phosphatase 5 DUSP5 Tbio Enzyme -2.50738 309.0 198
Protein FAM166A FAM166A Tdark Non-IDG 0.00000 37
Zinc finger protein 844 ZNF844 Tdark Transcription Factor 0.00000 21
Cytochrome P450 1B1 CYP1B1 Tchem Non-IDG -2.93702 904.4 260
Ceramide glucosyltransferase UGCG Tclin Enzyme -2.17676 128.8 135
Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 SVEP1 Tbio Non-IDG -1.04504 14.5 11
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 PLCE1 Tbio Enzyme -1.96455 94.9 28