Development Level

Tbio 223 | 11,445
Tchem 61 | 1,598
Tclin 25 | 613
Tdark 24 | 6,588

Collection

RFA-RM-18-021 2 | 328
GPCR: IDG Consortium (Complete... 1 | 25
Ion Channel: IDG Consortium (T... 1 | 99
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, incomple... 11 | 499
decreased bone mineral density 7 | 126
preweaning lethality, complete... 7 | 979
decreased circulating glucose ... 6 | 126
decreased total body fat amoun... 6 | 207
decreased vertical activity 6 | 208
enlarged heart 6 | 210
hypoactivity 5 | 132
abnormal behavior 4 | 298
abnormal embryo size 4 | 220
abnormal eye morphology 4 | 68
abnormal heart morphology 4 | 162
abnormal lens morphology 4 | 81
abnormal retina morphology 4 | 71
decreased bone mineral content 4 | 151
decreased grip strength 4 | 116
embryonic lethality prior to t... 4 | 278
increased bone mineral density 4 | 72
increased or absent threshold ... 4 | 101
male infertility 4 | 123
abnormal bone structure 3 | 187
abnormal neural tube closure 3 | 46
abnormal retinal vasculature m... 3 | 27
cataract 3 | 92
decreased body length 3 | 101
decreased caudal vertebrae num... 3 | 53
decreased circulating HDL chol... 3 | 68
decreased circulating choleste... 3 | 93
decreased circulating insulin ... 3 | 76
decreased circulating serum al... 3 | 82
decreased leukocyte cell numbe... 3 | 73
decreased mean corpuscular vol... 3 | 79
increased bone mineral content 3 | 108
increased circulating HDL chol... 3 | 80
increased circulating alkaline... 3 | 122
increased circulating bilirubi... 3 | 16
increased circulating choleste... 3 | 66
increased circulating sodium l... 3 | 71
increased circulating triglyce... 3 | 42
increased lean body mass 3 | 172
increased total body fat amoun... 3 | 134
short tibia 3 | 97
thrombocytopenia 3 | 56
abnormal behavioral response t... 2 | 66
abnormal coat-hair pigmentatio... 2 | 64
abnormal femur morphology 2 | 14
abnormal forebrain development 2 | 20
abnormal hindbrain development 2 | 16
abnormal hindbrain morphology 2 | 10
abnormal kidney morphology 2 | 65
abnormal midbrain development 2 | 20
abnormal seminal vesicle morph... 2 | 114
abnormal spleen morphology 2 | 55
abnormal urinary bladder morph... 2 | 11
decreased circulating phosphat... 2 | 27
decreased circulating potassiu... 2 | 20
decreased circulating triglyce... 2 | 79
decreased erythrocyte cell num... 2 | 62
decreased large unstained cell... 2 | 11
decreased lean body mass 2 | 135
embryonic lethality prior to o... 2 | 239
enlarged kidney 2 | 14
female infertility 2 | 60
increased circulating alanine ... 2 | 13
increased mean corpuscular hem... 2 | 96
increased mean corpuscular hem... 2 | 36
increased mean corpuscular vol... 2 | 92
increased startle reflex 2 | 112
small kidney 2 | 16
small spleen 2 | 19
small uterus 2 | 3
abnormal craniofacial morpholo... 1 | 33
abnormal cranium morphology 1 | 36
abnormal locomotor activation 1 | 16
abnormal optic disc morphology 1 | 10
abnormal startle reflex 1 | 15
abnormal tooth morphology 1 | 24
absent pinna reflex 1 | 23
decreased blood urea nitrogen ... 1 | 51
decreased circulating amylase ... 1 | 28
decreased circulating chloride... 1 | 30
decreased circulating sodium l... 1 | 22
decreased eosinophil cell numb... 1 | 24
decreased food intake 1 | 13
decreased mean corpuscular hem... 1 | 31
decreased red blood cell distr... 1 | 41
enlarged spleen 1 | 41
impaired pupillary reflex 1 | 26
impaired righting response 1 | 26
increased anti-nuclear antigen... 1 | 19
increased blood urea nitrogen ... 1 | 48
increased circulating creatini... 1 | 38
increased heart weight 1 | 62
iris synechia 1 | 3
limb grasping 1 | 41
persistence of hyaloid vascula... 1 | 33
stereotypic behavior 1 | 3
thin ventricular wall 1 | 24
tremors 1 | 39
trunk curl 1 | 16

Disease

nephrosclerosis 333 | 333
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
lung cancer 4,740 | 4,740
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Urinary Tract 328 | 16,678
Digestive Tract 326 | 17,369
Liver and Pancreas 324 | 16,750
Endocrine System 321 | 18,159
Male tissues 320 | 17,142
Female tissues 317 | 17,400
Skin and soft tissues 317 | 17,230
Nervous System 316 | 16,725
Blood and immune system 313 | 16,909
Respiratory system 307 | 16,393
Cardiovascular System 287 | 15,192

Target Family

Non-IDG 150 | 12,091
Enzyme 101 | 4,145
Transporter 27 | 473
Transcription Factor 21 | 1,400
Kinase 19 | 634
GPCR 6 | 408
Ion Channel 5 | 344
Nuclear Receptor 4 | 48

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Alcohol dehydrogenase 6 ADH6 Tbio Enzyme -1.84121 71.7 117
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 DDAH1 Tchem Enzyme -2.13636 144.4 205
Hairy/enhancer-of-split related with YRPW motif protein 1 HEY1 Tbio Transcription Factor -2.28398 163.4 335
Solute carrier family 13 member 3 SLC13A3 Tbio Transporter -1.47363 31.7 92
DnaJ homolog subfamily C member 12 DNAJC12 Tbio Non-IDG -0.86435 8.56 51
Growth/differentiation factor 15 GDF15 Tbio Non-IDG -2.84344 761.3 702
Transient receptor potential cation channel subfamily V member 2 TRPV2 Tchem Ion Channel -2.28525 197.9 203
Endomucin EMCN Tbio Non-IDG -1.34688 22.9 136
2-oxoglutarate dehydrogenase-like, mitochondrial OGDHL Tbio Enzyme -0.59292 3.63 46
Harmonin USH1C Tbio Non-IDG -2.10689 124.7 188