Development Level

Tbio 310 | 10,625
Tchem 82 | 1,890
Tdark 68 | 7,003
Tclin 20 | 602

Collection

Eligible non-olfactory GPCR Proteins 5 | 145
Eligible Ion Channel Proteins 2 | 117
Eligible Kinase Proteins 1 | 134

IMPC Term

preweaning lethality, complete... 14 | 633
decreased lean body mass 8 | 195
preweaning lethality, incomple... 8 | 260
abnormal behavior 6 | 226
decreased mean corpuscular vol... 6 | 50
embryonic lethality prior to t... 6 | 187
enlarged heart 6 | 111
abnormal lens morphology 5 | 73
decreased circulating insulin ... 5 | 75
increased circulating alkaline... 5 | 119
abnormal heart morphology 4 | 51
decreased mean corpuscular hem... 4 | 34
decreased total body fat amoun... 4 | 186
increased circulating serum al... 4 | 25
increased lean body mass 4 | 107
increased rib number 4 | 41
abnormal bone structure 3 | 131
abnormal cornea morphology 3 | 24
abnormal retinal pigmentation 3 | 61
cardiovascular system phenotyp... 3 | 35
decreased body length 3 | 108
decreased body weight 3 | 174
decreased bone mineral content 3 | 157
decreased circulating triglyce... 3 | 83
decreased grip strength 3 | 123
decreased hemoglobin content 3 | 53
hyperactivity 3 | 108
increased bone mineral content 3 | 92
increased circulating total pr... 3 | 20
increased mean corpuscular vol... 3 | 91
increased total body fat amoun... 3 | 57
male infertility 3 | 62
abnormal cranium morphology 2 | 32
abnormal embryo size 2 | 112
abnormal epididymis morphology 2 | 31
abnormal gait 2 | 51
abnormal maxilla morphology 2 | 16
abnormal retina morphology 2 | 100
abnormal seminal vesicle morph... 2 | 47
abnormal skin morphology 2 | 23
abnormal sleep behavior 2 | 63
abnormal thoracic vertebrae mo... 2 | 16
cataract 2 | 26
corneal opacity 2 | 25
decreased CD8-positive, alpha-... 2 | 26
decreased NK T cell number 2 | 28
decreased circulating HDL chol... 2 | 77
decreased circulating iron lev... 2 | 25
decreased circulating serum al... 2 | 79
decreased fasted circulating g... 2 | 49
decreased heart weight 2 | 44
decreased mean corpuscular hem... 2 | 19
decreased mean platelet volume 2 | 12
decreased startle reflex 2 | 48
decreased vertical activity 2 | 22
embryonic lethality prior to o... 2 | 148
enlarged lymph nodes 2 | 27
hypoactivity 2 | 89
immune system phenotype 2 | 17
increased blood urea nitrogen ... 2 | 44
increased body length 2 | 20
increased circulating calcium ... 2 | 32
increased circulating potassiu... 2 | 31
increased fasted circulating g... 2 | 68
increased grip strength 2 | 83
increased heart weight 2 | 37
increased hematocrit 2 | 36
increased mean platelet volume 2 | 19
limb grasping 2 | 35
short tibia 2 | 82
straub tail 2 | 26
thrombocytopenia 2 | 46
tremors 2 | 34
abnormal coping response 1 | 12
abnormal embryo turning 1 | 15
abnormal kidney morphology 1 | 30
abnormal lung morphology 1 | 15
abnormal neural tube morpholog... 1 | 8
abnormal rib morphology 1 | 28
abnormal spleen morphology 1 | 36
abnormal tail movements 1 | 12
decreased NK cell number 1 | 16
decreased T cell number 1 | 31
decreased bone mineral density 1 | 126
decreased cervical vertebrae n... 1 | 12
decreased circulating bilirubi... 1 | 14
decreased circulating chloride... 1 | 32
decreased circulating potassiu... 1 | 17
decreased effector memory CD8-... 1 | 24
decreased eosinophil cell numb... 1 | 41
decreased lumbar vertebrae num... 1 | 62
embryonic growth retardation 1 | 28
enlarged spleen 1 | 26
female infertility 1 | 34
increased circulating HDL chol... 1 | 63
increased circulating magnesiu... 1 | 10
increased effector memory CD4-... 1 | 15
increased sacral vertebrae num... 1 | 62
premature death 1 | 5
prenatal lethality prior to he... 1 | 64

Disease

mucosa-associated lymphoid tissue lymphoma 480 | 480
ovarian cancer 8,492 | 8,492
osteosarcoma 7,933 | 7,933
psoriasis 6,685 | 6,685
medulloblastoma, large-cell 6,234 | 6,234
glioblastoma 5,572 | 5,572
lung cancer 4,473 | 4,473
atypical teratoid / rhabdoid tumor 4,369 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 3,289 | 3,289
malignant mesothelioma 3,163 | 3,163
Breast cancer 3,099 | 3,099
pilocytic astrocytoma 3,086 | 3,086
primitive neuroectodermal tumor 3,031 | 3,031
intraductal papillary-mucinous carcinoma (IPMC) 2,988 | 2,988
intraductal papillary-mucinous adenoma (IPMA) 2,956 | 2,956
invasive ductal carcinoma 2,950 | 2,950
oligodendroglioma 2,849 | 2,849
lung carcinoma 2,844 | 2,844
non-small cell lung cancer 2,798 | 2,798
lung adenocarcinoma 2,714 | 2,714
pediatric high grade glioma 2,712 | 2,712
ependymoma 2,514 | 2,514
Cancer 2,346 | 2,346
pancreatic cancer 2,300 | 2,300
interstitial cystitis 2,299 | 2,299
subependymal giant cell astrocytoma 2,287 | 2,287
group 3 medulloblastoma 2,254 | 2,254
astrocytic glioma 2,241 | 2,241
adult high grade glioma 2,148 | 2,148
Carcinoma 2,147 | 2,147
ulcerative colitis 2,087 | 2,087
pituitary cancer 1,972 | 1,972
Pick disease 1,893 | 1,893
group 4 medulloblastoma 1,875 | 1,875
pancreatic ductal adenocarcinoma liver metastasis 1,795 | 1,795
ductal carcinoma in situ 1,745 | 1,745
cystic fibrosis 1,670 | 1,670
diabetes mellitus 1,663 | 1,663
breast carcinoma 1,614 | 1,614
tuberculosis 1,563 | 1,563
posterior fossa group B ependymoma 1,530 | 1,530
medulloblastoma 1,524 | 1,524
posterior fossa group A ependymoma 1,511 | 1,511
astrocytoma 1,493 | 1,493
sonic hedgehog group medulloblastoma 1,482 | 1,482
colon cancer 1,475 | 1,475
adrenocortical carcinoma 1,427 | 1,427
Multiple myeloma 1,328 | 1,328
primary pancreatic ductal adenocarcinoma 1,271 | 1,271
juvenile dermatomyositis 1,189 | 1,189
Rheumatoid Arthritis 1,171 | 1,171
acute quadriplegic myopathy 1,157 | 1,157
atypical teratoid/rhabdoid tumor 1,095 | 1,095
spina bifida 1,064 | 1,064
cutaneous lupus erythematosus 1,056 | 1,056
nasopharyngeal carcinoma 1,056 | 1,056
dermatomyositis 967 | 967
Atopic dermatitis 944 | 944
active Crohn's disease 918 | 918
non primary Sjogren syndrome sicca 840 | 840
gastric carcinoma 832 | 832
primary Sjogren syndrome 789 | 789
acute myeloid leukemia 785 | 785
Waldenstrons macroglobulinemia 765 | 765
esophageal adenocarcinoma 737 | 737
tuberculosis and treatment for 6 months 686 | 686
progressive supranuclear palsy 674 | 674
aldosterone-producing adenoma 664 | 664
Alzheimer's disease 644 | 644
Obesity 616 | 616
Duchenne muscular dystrophy 602 | 602
Intellectual disability 573 | 573
pancreatic carcinoma 567 | 567
fibroadenoma 557 | 557
hepatocellular carcinoma 550 | 550
Down syndrome 548 | 548
Endometriosis 535 | 535
chronic rhinosinusitis 512 | 512
Schizophrenia 503 | 503
autosomal dominant Emery-Dreifuss muscular dystrophy 499 | 499
Multiple Sclerosis 498 | 498
active ulcerative colitis 477 | 477
Prostatic Neoplasms 471 | 471
IGA Glomerulonephritis 454 | 454
gastric cancer 436 | 436
Amyotrophic Lateral Sclerosis 432 | 432
non-small cell lung carcinoma 413 | 413
Mammary Neoplasms 410 | 410
inflammatory breast cancer 404 | 404
Kidney disease 397 | 397
Neurodegenerative disease 383 | 383
sarcoidosis 368 | 368
Parkinson's disease 364 | 364
Asthma 349 | 349
glioblastoma multiforme 347 | 347
Epilepsy 346 | 346
Polycystic Ovary Syndrome 335 | 335
nephrosclerosis 329 | 329
tuberculosis and treatment for 3 months 327 | 327
Autistic Disorder 320 | 320

Tissue

Digestive Tract 474 | 18,473
Blood and immune system 473 | 17,995
Urinary Tract 473 | 18,444
Female tissues 472 | 18,647
Liver and Pancreas 472 | 18,136
Nervous System 472 | 18,561
Endocrine System 471 | 18,512
Respiratory system 471 | 17,484
Cardiovascular System 470 | 17,958
Male tissues 470 | 17,969
Skin and soft tissues 469 | 18,115

Target Family

Non-IDG 296 | 11,969
Enzyme 101 | 4,146
GPCR 20 | 408
Transcription Factor 20 | 1,400
Transporter 16 | 473
Kinase 14 | 634
Ion Channel 6 | 341
Epigenetic 3 | 242
Nuclear Receptor 3 | 48
TF/Epigenetic 1 | 38

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Carcinoembryonic antigen-related cell adhesion molecule 8 CEACAM8 Tbio Non-IDG -2.25741 172.1 240
Low affinity immunoglobulin gamma Fc region receptor II-b FCGR2B Tbio Non-IDG -2.59865 595.2 386
Sodium/bile acid cotransporter 5 SLC10A5 Tdark Transporter -0.04186 1.15 24
Short-chain dehydrogenase/reductase family 42E member 1 SDR42E1 Tdark Enzyme 0.00000 11
GTPase IMAP family member 4 GIMAP4 Tbio Enzyme -0.97980 10.2 121
Calcium-dependent secretion activator 2 CADPS2 Tbio Non-IDG -1.08328 13.0 28
Zinc finger protein 404 ZNF404 Tdark Transcription Factor 0.48 0.00000 29
Secreted and transmembrane protein 1 SECTM1 Tbio Non-IDG -0.82741 8.01 59
Oncostatin-M-specific receptor subunit beta OSMR Tbio Non-IDG -2.24105 170.5 217
Sorting nexin-24 SNX24 Tdark Non-IDG 0.40 0.57 106