Development Level

Tbio 3,336 | 11,445
Tdark 601 | 6,588
Tchem 579 | 1,598
Tclin 224 | 613

Collection

Kinase: IDG Consortium (Target... 23 | 125
GPCR: IDG Consortium (Targets) 19 | 126
Ion Channel: IDG Consortium (T... 18 | 99
Kinase: IDG Consortium (Comple... 9 | 37
GPCR: IDG Consortium (Complete... 8 | 25

IMPC Phenotype

preweaning lethality, complete... 302 | 979
preweaning lethality, incomple... 166 | 499
embryonic lethality prior to t... 83 | 278
abnormal behavior 78 | 298
enlarged heart 77 | 210
decreased total body fat amoun... 76 | 207
embryonic lethality prior to o... 73 | 239
abnormal embryo size 68 | 220
decreased vertical activity 59 | 208
increased lean body mass 58 | 172
decreased body weight 56 | 161
abnormal bone structure 55 | 187
abnormal heart morphology 50 | 162
hypoactivity 44 | 132
increased startle reflex 44 | 112
increased circulating alkaline... 41 | 122
increased total body fat amoun... 40 | 134
cataract 38 | 92
hyperactivity 38 | 148
increased bone mineral content 38 | 108
decreased lean body mass 36 | 135
decreased bone mineral density 35 | 126
decreased circulating glucose ... 33 | 126
decreased grip strength 33 | 116
increased bone mineral density 33 | 72
decreased bone mineral content 32 | 151
increased or absent threshold ... 31 | 101
male infertility 31 | 123
abnormal eye morphology 30 | 68
abnormal lens morphology 30 | 81
embryonic growth retardation 30 | 106
decreased body length 28 | 101
decreased circulating choleste... 28 | 93
decreased prepulse inhibition 28 | 82
prenatal lethality prior to he... 28 | 87
abnormal seminal vesicle morph... 27 | 114
increased mean corpuscular vol... 27 | 92
short tibia 27 | 97
decreased circulating triglyce... 26 | 79
decreased lymphocyte cell numb... 26 | 83
decreased startle reflex 26 | 75
improved glucose tolerance 26 | 79
increased heart weight 26 | 62
decreased circulating serum al... 25 | 82
increased mean corpuscular hem... 25 | 96
abnormal retina morphology 24 | 71
impaired glucose tolerance 24 | 75
abnormal sleep behavior 23 | 70
decreased mean corpuscular vol... 23 | 79
increased circulating HDL chol... 23 | 80
abnormal gait 22 | 69
abnormal skin morphology 22 | 50
decreased erythrocyte cell num... 22 | 62
increased circulating sodium l... 22 | 71
increased fasted circulating g... 22 | 76
abnormal kidney morphology 21 | 65
decreased circulating HDL chol... 21 | 68
decreased circulating insulin ... 21 | 76
decreased hemoglobin content 20 | 68
decreased mean corpuscular hem... 20 | 50
increased monocyte cell number 20 | 63
thrombocytopenia 20 | 56
decreased caudal vertebrae num... 19 | 53
abnormal neural tube closure 18 | 46
decreased leukocyte cell numbe... 18 | 73
increased circulating choleste... 18 | 66
increased circulating triglyce... 18 | 42
abnormal behavioral response t... 17 | 66
decreased circulating alanine ... 17 | 47
decreased circulating total pr... 17 | 49
edema 17 | 59
enlarged lymph nodes 17 | 37
limb grasping 17 | 41
abnormal coat-hair pigmentatio... 16 | 64
abnormal spleen morphology 16 | 55
decreased fasted circulating g... 16 | 65
decreased hematocrit 16 | 46
increased circulating chloride... 16 | 41
increased hematocrit 16 | 46
abnormal bone mineralization 15 | 38
decreased blood urea nitrogen ... 15 | 51
decreased circulating aspartat... 15 | 34
enlarged spleen 15 | 41
increased erythrocyte cell num... 15 | 39
increased leukocyte cell numbe... 15 | 47
increased neutrophil cell numb... 15 | 46
small superior vagus ganglion 15 | 74
tremors 15 | 39
abnormal cranium morphology 14 | 36
female infertility 14 | 60
increased blood urea nitrogen ... 14 | 48
increased body length 14 | 32
increased circulating calcium ... 14 | 34
small testis 14 | 58
decreased heart left ventricle... 13 | 28
increased mean platelet volume 13 | 45
abnormal cornea morphology 12 | 31
hydrometra 12 | 53
pale yolk sac 12 | 25
pallor 12 | 34

Disease

lung cancer 4,740 | 4,740
Carcinoma 11,493 | 11,493
ovarian cancer 8,520 | 8,520
osteosarcoma 7,950 | 7,950
psoriasis 6,694 | 6,694
medulloblastoma, large-cell 6,241 | 6,241
glioblastoma 5,792 | 5,792
atypical teratoid / rhabdoid tumor 5,112 | 5,112
ependymoma 4,679 | 4,679
group 3 medulloblastoma 4,104 | 4,104
adult high grade glioma 3,801 | 3,801
Breast cancer 3,578 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 3,291 | 3,291
malignant mesothelioma 3,232 | 3,232
Astrocytoma, Pilocytic 3,081 | 3,081
primitive neuroectodermal tumor 3,035 | 3,035
intraductal papillary-mucinous carcinoma (IPMC) 2,989 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 2,955 | 2,955
invasive ductal carcinoma 2,951 | 2,951
non-small cell lung cancer 2,890 | 2,890
oligodendroglioma 2,850 | 2,850
lung carcinoma 2,843 | 2,843
lung adenocarcinoma 2,716 | 2,716
Kidney cancer 2,613 | 2,613
astrocytic glioma 2,597 | 2,597
Cancer 2,499 | 2,499
pancreatic cancer 2,398 | 2,398
interstitial cystitis 2,312 | 2,312
subependymal giant cell astrocytoma 2,287 | 2,287
tuberculosis 2,010 | 2,010
pituitary cancer 1,972 | 1,972
pancreatic ductal adenocarcinoma liver metastasis 1,962 | 1,962
Pick disease 1,894 | 1,894
group 4 medulloblastoma 1,855 | 1,855
ulcerative colitis 1,819 | 1,819
ductal carcinoma in situ 1,745 | 1,745
diabetes mellitus 1,728 | 1,728
cystic fibrosis 1,696 | 1,696
breast carcinoma 1,638 | 1,638
colon cancer 1,478 | 1,478
Autosomal recessive predisposition 1,442 | 1,442
adrenocortical carcinoma 1,428 | 1,428
Multiple myeloma 1,332 | 1,332
Rheumatoid arthritis 1,191 | 1,191
juvenile dermatomyositis 1,187 | 1,187
Schizophrenia 1,160 | 1,160
acute quadriplegic myopathy 1,158 | 1,158
astrocytoma 1,146 | 1,146
primary pancreatic ductal adenocarcinoma 1,109 | 1,109
spina bifida 1,074 | 1,074
pediatric high grade glioma 1,064 | 1,064
nasopharyngeal carcinoma 1,058 | 1,058
cutaneous lupus erythematosus 1,057 | 1,057
Intellectual disability 1,016 | 1,016
dermatomyositis 966 | 966
Atopic dermatitis 952 | 952
active Crohn's disease 922 | 922
non primary Sjogren syndrome sicca 891 | 891
gastric carcinoma 807 | 807
Epilepsy 792 | 792
acute myeloid leukemia 783 | 783
Liver Cirrhosis, Experimental 769 | 769
Waldenstrons macroglobulinemia 765 | 765
active ulcerative colitis 764 | 764
esophageal adenocarcinoma 737 | 737
primary Sjogren syndrome 735 | 735
medulloblastoma 720 | 720
Melanoma 711 | 711
Obesity 678 | 678
progressive supranuclear palsy 676 | 676
Bipolar Disorder 666 | 666
aldosterone-producing adenoma 665 | 665
Alzheimer's disease 658 | 658
Dull intelligence 645 | 645
Low intelligence 645 | 645
Mental Retardation 645 | 645
Mental deficiency 645 | 645
Poor school performance 645 | 645
Cognitive delay 608 | 608
Global developmental delay 608 | 608
Mental and motor retardation 608 | 608
Liver cancer 604 | 604
Duchenne muscular dystrophy 601 | 601
Seizures 596 | 596
Muscle hypotonia 571 | 571
pancreatic carcinoma 562 | 562
fibroadenoma 559 | 559
hepatocellular carcinoma 547 | 547
Endometriosis 540 | 540
Multiple Sclerosis 540 | 540
Short stature 531 | 531
chronic rhinosinusitis 512 | 512
autosomal dominant Emery-Dreifuss muscular dystrophy 510 | 510
Down syndrome 499 | 499
Prostatic Neoplasms 495 | 495
mucosa-associated lymphoid tissue lymphoma 484 | 484
Skin cancer 469 | 469
posterior fossa group A ependymoma 468 | 468
sonic hedgehog group medulloblastoma 467 | 467
gastric cancer 459 | 459

Tissue

Endocrine System 4,646 | 18,159
Female tissues 4,605 | 17,400
Digestive Tract 4,595 | 17,369
Male tissues 4,584 | 17,142
Skin and soft tissues 4,581 | 17,230
Blood and immune system 4,559 | 16,909
Urinary Tract 4,559 | 16,678
Liver and Pancreas 4,553 | 16,750
Nervous System 4,538 | 16,725
Respiratory system 4,530 | 16,393
Cardiovascular System 4,375 | 15,192

Target Family

Non-IDG 2,674 | 12,091
Enzyme 1,101 | 4,145
Transcription Factor 353 | 1,400
Kinase 213 | 634
Transporter 114 | 473
GPCR 84 | 408
Ion Channel 81 | 344
Epigenetic 72 | 242
Nuclear Receptor 17 | 48
oGPCR 16 | 421
TF/Epigenetic 15 | 38

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Retinoic acid receptor responder protein 3 RARRES3 Tbio Non-IDG -1.84020 71.0 164
Suppressor of tumorigenicity 14 protein ST14 Tchem Non-IDG -2.50215 338.3 309
T-complex protein 1 subunit zeta CCT6A Tbio Non-IDG -1.39880 26.2 90
Paraneoplastic antigen Ma2 PNMA2 Tbio Non-IDG -2.92781 822.4 113
Ras-related protein Rab-21 RAB21 Tbio Enzyme -1.33715 23.1 275
Adenylate kinase 2, mitochondrial AK2 Tbio Kinase -2.00007 98.7 330
Beta-1,4-galactosyltransferase 1 B4GALT1 Tbio Enzyme -2.34454 211.1 130
Heme-binding protein 2 HEBP2 Tbio Non-IDG -1.05941 10.8 114
Disintegrin and metalloproteinase domain-containing protein 28 ADAM28 Tbio Enzyme -1.87527 79.6 110
Eukaryotic translation initiation factor 1 EIF1 Tbio Non-IDG -2.06392 118.5 92